2008
Chapter 5 Functional Modulators Linking Inflow with Outflow of Aqueous Humor
Coca‐Prados M, Ghosh S. Chapter 5 Functional Modulators Linking Inflow with Outflow of Aqueous Humor. Current Topics In Membranes 2008, 62: 123-160. DOI: 10.1016/s1063-5823(08)00405-5.Peer-Reviewed Original ResearchCiliary epitheliumAqueous humorHuman ocular ciliary epitheliumMultiple neuroendocrine factorsTrabecular meshwork cellsOcular ciliary epitheliumImmune homeostasisMain cell typesEndocrine loopVasoactive peptidesAnterior segmentCircuitry mechanismsEndocrine factorsNeuroendocrine factorsSteroid hormonesOutflow pathwayNeuroendocrine circuitryMeshwork cellsRegulatory peptidesFunctional modulatorsAqHAvascular tissueCircadian rhythmTissueCell types
2007
New perspectives in aqueous humor secretion and in glaucoma: The ciliary body as a multifunctional neuroendocrine gland
Coca-Prados M, Escribano J. New perspectives in aqueous humor secretion and in glaucoma: The ciliary body as a multifunctional neuroendocrine gland. Progress In Retinal And Eye Research 2007, 26: 239-262. PMID: 17321191, DOI: 10.1016/j.preteyeres.2007.01.002.Peer-Reviewed Original ResearchConceptsIntraocular pressureCiliary bodyAqueous humor secretionAqueous humorCiliary epitheliumGlaucoma-associated genesImmune privilege statusDevelopment of glaucomaGlutamate-metabolizing enzymesPathophysiology of glaucomaAnti-angiogenic factorsSteroid-converting enzymesDiurnal circadian rhythmCiliary blood flowOcular ciliary bodyAnterior segmentBlood flowMultifactorial eventGlaucomaNeuroendocrine systemOutflow pathwayEndocrine communicationEndocrine systemEndocrine peptidesRegulatory peptides
1999
Differential gene expression in the human ciliary epithelium
Coca-Prados M, Escribano J, Ortego J. Differential gene expression in the human ciliary epithelium. Progress In Retinal And Eye Research 1999, 18: 403-429. PMID: 10192520, DOI: 10.1016/s1350-9462(98)00026-3.Peer-Reviewed Original ResearchConceptsDifferential gene expressionCell-specific expressionDiversity of functionsExpression of genesOcular ciliary bodySubtractive libraryNeuropeptide processing enzymesMolecular basisGene expressionCultured ciliary epithelial cellsCell differentiationCiliary epitheliumHuman ciliary epitheliumAntioxidative enzymesGenesCiliary epithelial cellsRegulatory peptidesLight-dark cycleEpithelial cellsMuscle cellsCiliary muscle cellsAutocrine mechanismExpressionPlasma proteinsParacrine mechanisms