Quantitative distribution of Zn, Fe and Cu in the human lens and study of the Zn–metallothionein redox system in cultured lens epithelial cells by elemental MS
González-Iglesias H, Petrash C, Rodríguez-Menéndez S, García M, Álvarez L, Fernández-Vega Cueto L, Fernández B, Pereiro R, Sanz-Medel A, Coca-Prados M. Quantitative distribution of Zn, Fe and Cu in the human lens and study of the Zn–metallothionein redox system in cultured lens epithelial cells by elemental MS. Journal Of Analytical Atomic Spectrometry 2017, 32: 1746-1756. DOI: 10.1039/c6ja00431h.Peer-Reviewed Original ResearchLens epithelial cellsMolecular mass proteinsMass proteinsCultured human lens epithelial cellsHigh molecular mass proteinsEpithelial cellsCultured lens epithelial cellsHuman lens epithelial cellsHuman lensOxidative cellular damageLocalization of ZnEndogenous stressorsImportant enzymeMT proteinCellular distributionLens epithelial cell layerProteinRedox systemEpithelial cell layerElemental mass spectrometryCellular damageMetallothioneinOxidative stressHuman lensesCells