2020
Systemic Alterations of Immune Response-Related Proteins during Glaucoma Development in the Murine Model DBA/2J
Cueto A, Álvarez L, García M, Artime E, Barrios A, Rodríguez-Uña I, Coca-Prados M, González-Iglesias H. Systemic Alterations of Immune Response-Related Proteins during Glaucoma Development in the Murine Model DBA/2J. Diagnostics 2020, 10: 425. PMID: 32585848, PMCID: PMC7345206, DOI: 10.3390/diagnostics10060425.Peer-Reviewed Original ResearchImmune responseSystemic levelsOptic nerve damageImportant molecular changesDiagnosis of glaucomaComplement factor HCandidate molecular biomarkersGlaucomatous miceAdvanced diseaseNerve damageControl miceGlaucoma developmentComplement system proteinsSystemic alterationsDBA/2J miceAnimal modelsComplement C4AFicolin-3Potential biomarkersDifferent experimental groupsEnzyme immunoassayApolipoprotein A4Neurodegenerative diseasesGlaucomaSerum samples
2014
Characterization of Vitamin D Production by Human Ocular Barrier CellsVitamin D Production by Human Ocular Barrier Cells
Alsalem JA, Patel D, Susarla R, Coca-Prados M, Bland R, Walker EA, Rauz S, Wallace GR. Characterization of Vitamin D Production by Human Ocular Barrier CellsVitamin D Production by Human Ocular Barrier Cells. Investigative Ophthalmology & Visual Science 2014, 55: 2140-2147. PMID: 24576880, DOI: 10.1167/iovs.13-13019.Peer-Reviewed Original ResearchConceptsHuman scleral fibroblastsVitamin D3Vitamin D receptorBarrier epithelial cellsPrimary human scleral fibroblastsEnzyme immunoassayD productionUltraviolet B sunlightEpithelial cellsVitamin D productionRetinal pigment epithelial cell lineBarrier cellsExtrarenal synthesisHydroxyvitamin D3Epithelial cell lineImmune regulationCiliary bodyD receptorExpression of componentsSkin precursorsODM-2Scleral fibroblastsBarrier sitesCorneal endothelialBarrier function