Featured Publications
Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome
Sukhodolsky DG, Walsh C, Koller WN, Eilbott J, Rance M, Fulbright RK, Zhao Z, Bloch MH, King R, Leckman JF, Scheinost D, Pittman B, Hampson M. Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome. Biological Psychiatry 2019, 87: 1063-1070. PMID: 31668476, PMCID: PMC7015800, DOI: 10.1016/j.biopsych.2019.07.035.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCross-Over StudiesHumansMagnetic Resonance ImagingNeurofeedbackSeverity of Illness IndexTicsTourette SyndromeConceptsSupplementary motor areaYale Global Tic Severity ScaleFunctional magnetic resonanceTic Severity ScaleReal-time functional magnetic resonanceTourette syndromeSeverity ScaleYale Global Tic Severity Scale-Total Tic ScoreTotal tic scorePrimary outcome measureSham control conditionReduction of ticsMagnetic resonanceSecondary outcomesSessions of neurofeedbackCrossover studyTic symptomsTic scoreOutcome measuresMotor areaSecondary measuresTic severityReal neurofeedbackEnd pointNeurofeedback interventionTime course of clinical change following neurofeedback
Rance M, Walsh C, Sukhodolsky DG, Pittman B, Qiu M, Kichuk SA, Wasylink S, Koller WN, Bloch M, Gruner P, Scheinost D, Pittenger C, Hampson M. Time course of clinical change following neurofeedback. NeuroImage 2018, 181: 807-813. PMID: 29729393, PMCID: PMC6454268, DOI: 10.1016/j.neuroimage.2018.05.001.Peer-Reviewed Original ResearchConceptsClinical changesSymptom changeTime courseBrain functionNeurofeedback studiesPotential clinical toolCrossover designControl interventionsReal neurofeedbackClinical toolTime pointsClinical populationsNeurofeedback effectsInterventionNeurofeedback sessionsNeurofeedbackCurrent brain stateWeeksBrain statesNew studiesCourseSessionsSymptoms
2023
Protocol description for a randomized controlled trial of fMRI neurofeedback for tics in adolescents with Tourette Syndrome
Awasthi J, Harris-Starling C, Kalvin C, Pittman B, Park H, Bloch M, Fernandez T, Sukhodolsky D, Hampson M. Protocol description for a randomized controlled trial of fMRI neurofeedback for tics in adolescents with Tourette Syndrome. Psychiatry Research Neuroimaging 2023, 336: 111692. PMID: 37673711, PMCID: PMC10722977, DOI: 10.1016/j.pscychresns.2023.111692.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAdolescentHumansMagnetic Resonance ImagingNeurofeedbackRandomized Controlled Trials as TopicTic DisordersTicsTourette SyndromeConceptsTourette syndromeFunctional magnetic resonance imagingStudy protocolChronic tic disorderSupplementary motor areaLower functional connectivityMagnetic resonance imagingResearch study protocolLarge trialsClinical trialsTic disordersMotor areaBrain areasControl groupResonance imagingBrain regionsNew trialsFunctional connectivityNeurofeedback interventionFMRI neurofeedbackNF protocolTrialsNF studiesSyndromeIntervention
2010
Neurobiological Substrates of Tourette's Disorder
Leckman JF, Bloch MH, Smith ME, Larabi D, Hampson M. Neurobiological Substrates of Tourette's Disorder. Journal Of Child And Adolescent Psychopharmacology 2010, 20: 237-247. PMID: 20807062, PMCID: PMC2958453, DOI: 10.1089/cap.2009.0118.Chapters
2008
Brain Areas Coactivating with Motor Cortex During Chronic Motor Tics and Intentional Movements
Hampson M, Tokoglu F, King RA, Constable RT, Leckman JF. Brain Areas Coactivating with Motor Cortex During Chronic Motor Tics and Intentional Movements. Biological Psychiatry 2008, 65: 594-599. PMID: 19111281, PMCID: PMC2679868, DOI: 10.1016/j.biopsych.2008.11.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainFemaleHumansIntentionMagnetic Resonance ImagingMaleMotor CortexMovementTic DisordersTourette SyndromeConceptsMotor cortexSupplementary motor areaControl subjectsBrain areasMotor ticsTic disordersTic movementsMotor areaTic-like movementsHealthy control subjectsChronic tic disorderNormal control subjectsChronic motor ticsNovel intervention strategiesFunctional neuroimaging studiesTic executionSevere ticsIntentional movementPatient's ticsMotor regionsPremonitory urgesBrain activity patternsAdult subjectsTic generationCortex