2024
Changes in hoarding-related beliefs and associated neural changes during a simulated discarding task after cognitive-behavioral treatment for hoarding disorder
Knowles K, Stevens M, Levy H, Tolin D. Changes in hoarding-related beliefs and associated neural changes during a simulated discarding task after cognitive-behavioral treatment for hoarding disorder. Journal Of Psychiatric Research 2024, 180: 473-481. PMID: 39547046, PMCID: PMC11606758, DOI: 10.1016/j.jpsychires.2024.11.017.Peer-Reviewed Original ResearchCognitive-behavioral therapyHoarding-related beliefsFunctional magnetic resonance imagingHoarding disorderNeural activityMaladaptive beliefsCourse of CBTGroup cognitive-behavioral therapyLeft anterior cingulate cortexLeft middle frontal gyrusAssociated with cognitive changesCognitive-behavioral treatmentAssociated with increased activityAnterior ventral insulaAnterior cingulate cortexMiddle frontal gyrusInferior temporal lobeLeft middle insulaCognitive-behavioralAssociated with specific changesFrontal gyrusCingulate cortexMiddle insulaNeural regionsVentral insulaFunctional imaging derived ADHD biotypes based on deep clustering: a study on personalized medication therapy guidance
Feng A, Zhi D, Feng Y, Jiang R, Fu Z, Xu M, Zhao M, Yu S, Stevens M, Sun L, Calhoun V, Sui J. Functional imaging derived ADHD biotypes based on deep clustering: a study on personalized medication therapy guidance. EClinicalMedicine 2024, 77: 102876. DOI: 10.1016/j.eclinm.2024.102876.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderAttention deficit hyperactivity disorder patientsFunctional network connectivityAttention Deficit Hyperactivity Disorder AdolescentTreatment of attention deficit hyperactivity disorderPeking University Sixth HospitalBackground Attention deficit hyperactivity disorderDeficit hyperactivity disorderTreated with methylphenidateADHD subtypesHyperactivity/impulsivity symptomsAdolescent brainMedical treatment effectsHyperactivity disorderCognitive performanceABCD studyProblem scoresNeuroimaging markersNeurodevelopmental disordersMedical treatmentChildhood onsetChina Postdoctoral Science FoundationNational Natural Science Foundation of ChinaNatural Science Foundation of ChinaPrimary medicationA randomized clinical trial to evaluate feasibility, tolerability, and preliminary target engagement for a novel executive working memory training in adolescents with ADHD
Sullivan A, Anderson J, Beatty M, Choi J, Jaccard J, Hawkins K, Pearlson G, Stevens M. A randomized clinical trial to evaluate feasibility, tolerability, and preliminary target engagement for a novel executive working memory training in adolescents with ADHD. Behaviour Research And Therapy 2024, 181: 104615. PMID: 39173523, PMCID: PMC11465636, DOI: 10.1016/j.brat.2024.104615.Peer-Reviewed Original ResearchExecutive working memoryAttention-deficit/hyperactivity disorderWorking memory trainingMemory trainingExecutive working memory taskIncreased working memory capacityMedium effect size improvementsEffect size improvementsSelf-rated motivationIntervention participantsTarget engagementTrial retentionWorking memoryAttention-deficit/hyperactivityDifficulty manipulationPlacebo-controlled studyMemory capacityTask accuracySize improvementsMemory contentIntervention tolerabilityTraining targetBehavioral changesPrimary outcome measureCoaching sessionsCortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group
Gao Y, Staginnus M, Group E, Gao Y, Staginnus M, Townend S, Arango C, Bajaj S, Banaschewski T, Barker E, Benegal V, Berluti K, Bernhard A, Blair R, Boateng C, Bokde A, Brandeis D, Buitelaar J, Burt S, Cardinale E, Castro-Fornieles J, Chen H, Chen X, Chester S, Colins O, Cornwell H, Craig M, Cubillo A, Desrivieres S, Díaz D, Dietrich A, Dong D, Dykstra A, Franke B, Freitag C, Glennon J, Gonzalez-Madruga K, Hagan C, Hoekstra P, Holla B, Hyde L, Ibrahim K, Jabeen N, Jackson R, Jiang Y, Kohls G, Konrad K, Kypta-Vivanco A, Lamers K, Ma R, Marsh A, Martinelli A, Martinot J, Michalska K, Ming Q, Minosse S, Mitchell C, Monk C, Murphy D, Mycue L, Naaijen J, Oosterling M, Passamonti L, Pauli R, Alonso M, Phillips H, Ploe M, Raschle N, Roberts R, Rogers J, Rosa-Justicia M, Sagar-Ouriaghli I, Schulze U, Schumann G, Sethi A, Smaragdi A, Sonuga-Barke E, Stadler C, Stevens M, Sukhodolsky D, Sully K, Sun X, Toschi N, Townsend C, van der Wee N, Vermeiren R, Viding E, Wang X, Westerman H, Wu Q, Yao S, Zhang J, Zhou J, Zhou J, Jahanshad N, Thomopoulos S, Ching C, Kang M, Thompson P, Klapwijk E, Pine D, Baskin-Sommers A, Cecil C, Aghajani M, Walton E, Fairchild G, De Brito S. Cortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group. The Lancet Psychiatry 2024, 11: 620-632. PMID: 39025633, DOI: 10.1016/s2215-0366(24)00187-1.Peer-Reviewed Original ResearchConceptsGroup-by-age interactionCallous-unemotional traitsConduct disorder groupConduct disorderBrain structural alterationsSubcortical volumesDisorder groupDiagnosis of conduct disorderCaudal anterior cingulate cortexAnalysis of structural MRI dataCortical thicknessT1-weighted MRI brain scansBrain structural correlatesAnterior cingulate cortexSuperior temporal sulcusStructural MRI dataAssess group differencesMRI brain scansNucleus accumbensADHD comorbidityCingulate cortexDisorder subtypesSmaller amygdalaBrain alterationsTemporal sulcusNeural Outcomes and Predictors of Cognitive-Behavioral Treatment for Hoarding Disorder
Stevens M, Levy H, Tolin D. Neural Outcomes and Predictors of Cognitive-Behavioral Treatment for Hoarding Disorder. Biological Psychiatry 2024, 95: s65. DOI: 10.1016/j.biopsych.2024.02.161.Peer-Reviewed Original Research75. Executive Working Memory Intervention Reduces Motor Activity in Adolescents With Attention-Deficit Hyperactivity Disorder
Beatty M, Sullivan A, Anderson J, Choi J, Pearlson G, Hawkins K, Bond D, Stevens M. 75. Executive Working Memory Intervention Reduces Motor Activity in Adolescents With Attention-Deficit Hyperactivity Disorder. Biological Psychiatry 2024, 95: s130. DOI: 10.1016/j.biopsych.2024.02.310.Peer-Reviewed Original Research73. Preliminary Efficacy Findings for a Placebo Controlled Randomized Clinical Trial of a Novel Executive Working Memory Training Intervention for Adolescents With ADHD
Sullivan A, Anderson J, Beatty M, Choi J, Jaccard J, Pearlson G, Stevens M. 73. Preliminary Efficacy Findings for a Placebo Controlled Randomized Clinical Trial of a Novel Executive Working Memory Training Intervention for Adolescents With ADHD. Biological Psychiatry 2024, 95: s129. DOI: 10.1016/j.biopsych.2024.02.308.Peer-Reviewed Original Research284. Insights to Cognitive Dynamics in Adolescents During an Incentivized Stroop Task Via Pupil Time-Course Analysis
Beatty M, Treadway M, Chase H, Stevens M. 284. Insights to Cognitive Dynamics in Adolescents During an Incentivized Stroop Task Via Pupil Time-Course Analysis. Biological Psychiatry 2024, 95: s216. DOI: 10.1016/j.biopsych.2024.02.783.Peer-Reviewed Original Research76. Better Learning Performance is Differentially Related to Neural Responses to Unsigned Prediction Errors Across Age in ADHD and Typically-Developing Adolescents
Chase H, Treadway M, Stevens M. 76. Better Learning Performance is Differentially Related to Neural Responses to Unsigned Prediction Errors Across Age in ADHD and Typically-Developing Adolescents. Biological Psychiatry 2024, 95: s130. DOI: 10.1016/j.biopsych.2024.02.311.Peer-Reviewed Original Research74. Functional Connectivity Changes as a Result of a Novel Executive Working Memory Training in Adolescents With ADHD
Sullivan A, Anderson J, Beatty M, Choi J, Jaccard J, Pearlson G, Stevens M. 74. Functional Connectivity Changes as a Result of a Novel Executive Working Memory Training in Adolescents With ADHD. Biological Psychiatry 2024, 95: s129-s130. DOI: 10.1016/j.biopsych.2024.02.309.Peer-Reviewed Original Research287. Younger Versus Older Adolescent Brains With Different Cognitive Reappraisal Styles Regulate Their Emotional Intensity in Different Ways
Stevens M, Novotny S, Pearlson G. 287. Younger Versus Older Adolescent Brains With Different Cognitive Reappraisal Styles Regulate Their Emotional Intensity in Different Ways. Biological Psychiatry 2024, 95: s217. DOI: 10.1016/j.biopsych.2024.02.786.Peer-Reviewed Original Research
2023
Estradiol effects on an emotional interference task in adolescents with current and remitted depression
Sullivan A, Chung Y, Novotny S, Epperson C, Kober H, Blumberg H, Gross J, Ochsner K, Pearlson G, Stevens M. Estradiol effects on an emotional interference task in adolescents with current and remitted depression. Hormones And Behavior 2023, 157: 105450. PMID: 37923628, PMCID: PMC10842169, DOI: 10.1016/j.yhbeh.2023.105450.Peer-Reviewed Original ResearchAttentional biasesFacial expressionsAdolescent femalesRemitted depressionEmotional facial expressionsNeutral facial expressionsEmotional interference taskAttention capture effectsMajor depressive disorderMDD groupResponse reaction timesGroups of participantsMain effectHappy stimuliInterference taskEmotional stimuliEmotional contentAI scoreControl adolescentsDisorder onsetInterference scoresGroup interactionMDD adolescentsSex hormone estradiolAdolescentsAn exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder
Worden B, Tolin D, Stevens M. An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder. Journal Of Affective Disorders 2023, 345: 410-418. PMID: 38706461, PMCID: PMC11068362, DOI: 10.1016/j.jad.2023.10.148.Peer-Reviewed Original ResearchCognitive behavioral therapyBrain activityEffective cognitive behavioral therapyCognitive-behavioral group therapyTreatment attendanceBrain dysfunctionFunctional magnetic resonanceDiscarding taskExecutive functioningAbnormal brain activityNeural predictorsHomework completionGroup therapyTreatment engagementHD patientsTreatment complianceHD treatmentPremotor areasActivity abnormalitiesPatient's abilityBrain regionsTherapeutic benefitTreatment retentionRegion activityPrior researchAn exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder.
Worden B, Tolin D, Stevens M. An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder. Journal Of Affective Disorders 2023 PMID: 39492520, DOI: 10.1016/j.jad.2023.10.148.Peer-Reviewed Original ResearchCognitive-behavioral therapyHoarding disorderBrain activityTreatment attendanceBrain dysfunctionCognitive-behavioral group therapyEffective cognitive-behavioral therapyAssociated with treatment attendanceFunctional magnetic resonanceAbnormal brain activityExecutive functionGroup therapyHomework completionTreatment retentionTreatment engagementBrain regionsActivation abnormalitiesRegional activityPremotor areasTreatment complianceInsulaCompliance variablesBrainPatient's abilityDisordersAge-related, multivariate associations between white matter microstructure and behavioral performance in three executive function domains
Anderson J, Calhoun V, Pearlson G, Hawkins K, Stevens M. Age-related, multivariate associations between white matter microstructure and behavioral performance in three executive function domains. Developmental Cognitive Neuroscience 2023, 64: 101318. PMID: 37875033, PMCID: PMC10618425, DOI: 10.1016/j.dcn.2023.101318.Peer-Reviewed Original ResearchConceptsExecutive function domainsResponse inhibitionWhite matter microstructureLower response inhibitionStructure-cognition relationshipsEF abilitiesBehavioral performanceCognitive imbalanceNeurocognitive testsFunction domainTest performanceYoung adulthoodFractional anisotropyBrain changesAge 12Young adultsSS performanceWhite matter FA valuesGreater relianceWhite matter changesWhite matter microstructural differencesSubjects ages 12White matter skeletonIndependent componentsMultivariate associationsLanguage Networks in Autism Spectrum Disorder: A systematic review of connectivity-based fMRI studies
Larson C, Thomas H, Crutcher J, Stevens M, Eigsti I. Language Networks in Autism Spectrum Disorder: A systematic review of connectivity-based fMRI studies. Review Journal Of Autism And Developmental Disorders 2023, 1-28. DOI: 10.1007/s40489-023-00382-6.Peer-Reviewed Original ResearchAutism spectrum disorderLanguage networkSpectrum disorderResting-state studiesFunctional neural connectivityNeurotypical peersASD symptomologyFMRI studyLanguage skillsFunctional connectivityCore featuresNeural connectivityNetwork regionsIdeal contextSocial functionLanguageConnectivityDisordersSymptomologyMixed patternPeersSkillsSystematic reviewPsychINFOIndividuals317. Bayesian Hierarchical Drift Diffusion Modeling of Decision-Making in Hoarding Disorder
Stevens M, Levy H, Tolin D. 317. Bayesian Hierarchical Drift Diffusion Modeling of Decision-Making in Hoarding Disorder. Biological Psychiatry 2023, 93: s222. DOI: 10.1016/j.biopsych.2023.02.557.Peer-Reviewed Original ResearchChanges in Neural Activity Following a Randomized Trial of Cognitive Behavioral Therapy for Hoarding Disorder
Tolin D, Levy H, Hallion L, Wootton B, Jaccard J, Diefenbach G, Stevens M. Changes in Neural Activity Following a Randomized Trial of Cognitive Behavioral Therapy for Hoarding Disorder. Journal Of Consulting And Clinical Psychology 2023, 91: 242-250. PMID: 36877480, PMCID: PMC10175200, DOI: 10.1037/ccp0000804.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMedial intraparietal areaDorsal anterior cingulate cortexIntraparietal areaHD patientsRostral cingulateDorsolateral prefrontalBehavioral therapyVentral insular cortexDACC activationAnterior intraparietal areaNeural activityGroup cognitive behavioral therapyAnterior cingulate cortexRight dorsolateral prefrontalFunctional magnetic resonance imagingMagnetic resonance imagingCaudal cingulateClinical trialsInsular cortexRight amygdalaTherapeutic benefitSymptom reductionCingulate cortexResonance imaging
2022
Associations of medication with subcortical morphology across the lifespan in OCD: Results from the international ENIGMA Consortium
Ivanov I, Boedhoe PSW, Abe Y, Alonso P, Ameis SH, Arnold PD, Balachander S, Baker JT, Banaj N, Bargalló N, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Brem S, Brennan BP, Buitelaar J, Calvo R, Cheng Y, Cho KIK, Dallaspezia S, Denys D, Diniz JB, Ely BA, Feusner JD, Ferreira S, Fitzgerald KD, Fontaine M, Gruner P, Hanna GL, Hirano Y, Hoexter MQ, Huyser C, Ikari K, James A, Jaspers-Fayer F, Jiang H, Kathmann N, Kaufmann C, Kim M, Koch K, Kwon JS, Lázaro L, Liu Y, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minuzzi L, Morer A, Morgado P, Nakagawa A, Nakamae T, Nakao T, Narayanaswamy JC, Nurmi EL, Oh S, Perriello C, Piacentini JC, Picó-Pérez M, Piras F, Piras F, Reddy YCJ, Manrique DR, Sakai Y, Shimizu E, Simpson HB, Soreni N, Soriano-Mas C, Spalletta G, Stern ER, Stevens MC, Stewart SE, Szeszko PR, Tolin DF, van Rooij D, Veltman DJ, van der Werf YD, van Wingen GA, Venkatasubramanian G, Walitza S, Wang Z, Watanabe A, Wolters LH, Xu X, Yun JY, Zarei M, Zhang F, Zhao Q, Jahanshad N, Thomopoulos SI, Thompson PM, Stein DJ, van den Heuvel OA, O'Neill J, Group T, Poletti S, Fridgeirsson E, Ikuta T, de Wit S, Vriend C, Kasprzak S, Kuno M, Takahashi J, Miguel E, Shavitt R, Hough M, Pariente J, Ortiz A, Bertolín S, Real E, Segalàs C, Moreira P, Sousa N, Narumoto J, Yamada K, Tang J, Fouche J, Kim T, Choi S, Ha M, Park S. Associations of medication with subcortical morphology across the lifespan in OCD: Results from the international ENIGMA Consortium. Journal Of Affective Disorders 2022, 318: 204-216. PMID: 36041582, DOI: 10.1016/j.jad.2022.08.084.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderUnmedicated patientsOlder adultsAssociation of medicationVolumes of putamenSubcortical brain structuresReuptake inhibitorsVentricular hypertrophyHippocampal atrophyMedicated patientsPsychotropic medicationsTherapeutic responseHippocampal volumeStriatal volumeSubcortical nucleiPatientsPsychotic disordersAntipsychoticsSubcortical morphologyStructural MRINormal agingBrain structuresBenzodiazepinesOCD patientsENIGMA consortiumFood cue reactivity in successful laparoscopic gastric banding: A sham-deflation-controlled pilot study
Koenis MMG, Ng J, Anderson B, Stevens MC, Tishler DS, Papasavas PK, Stone A, McLaughlin T, Verhaak A, Domakonda MJ, Pearlson GD. Food cue reactivity in successful laparoscopic gastric banding: A sham-deflation-controlled pilot study. Frontiers In Human Neuroscience 2022, 16: 902192. PMID: 36092648, PMCID: PMC9454014, DOI: 10.3389/fnhum.2022.902192.Peer-Reviewed Original ResearchLaparoscopic adjustable gastric bandingLateral occipital cortexGastric bandingOccipital cortexPilot studyWeight lossExcess weight lossAdjustable gastric bandingLaparoscopic gastric bandingSham-controlled designFood cue reactivityInferior temporal gyrusUnderlying neuronal mechanismsLAGB surgeryUnderwent removalNeuronal changesFrontal cortexLingual gyrusNeuronal mechanismsSurgery changesTemporal gyrusFood cravingsCue reactivityGyrusFood cues