RETRACTED: Where, when, how high, and how long? The hemodynamics of emotional response in psychotropic-naïve patients with adolescent bipolar disorder.
Wegbreit E, Passarotti AM, Ellis JA, Wu M, Witowski N, Fitzgerald JM, Stevens MC, Pavuluri MN. RETRACTED: Where, when, how high, and how long? The hemodynamics of emotional response in psychotropic-naïve patients with adolescent bipolar disorder. Journal Of Affective Disorders 2012, 147: 304-311. PMID: 23261134, PMCID: PMC3606663, DOI: 10.1016/j.jad.2012.11.025.Peer-Reviewed Original ResearchConceptsFearful facesPrefrontal cortexNeutral facesRight dorsolateral prefrontal cortexEmotion-attention interactionsEnhanced neural processingVentrolateral prefrontal cortexEmotional processing regionsDorsolateral prefrontal cortexAdolescent bipolar disorderProbe taskEmotional facesPrefrontal activityNeural processingSpaced stimuliABD groupEmotional responsesProcessing regionsBilateral amygdalaDisorder exhibitMixed mood statesMood statesHealthy controlsNeural activityBipolar disorder exhibitDiminished Frontostriatal Activity During Processing of Monetary Rewards and Losses in Pathological Gambling
Balodis IM, Kober H, Worhunsky PD, Stevens MC, Pearlson GD, Potenza MN. Diminished Frontostriatal Activity During Processing of Monetary Rewards and Losses in Pathological Gambling. Biological Psychiatry 2012, 71: 749-757. PMID: 22336565, PMCID: PMC3460522, DOI: 10.1016/j.biopsych.2012.01.006.Peer-Reviewed Original ResearchConceptsAlcohol dependencePathological gamblingVentral striatumMagnetic resonance imaging studyResonance imaging studyFunctional magnetic resonance imaging studyBrain activation changesMonetary incentive delay taskReward processingLoss processingPresent functional magnetic resonance imaging (fMRI) studyControl comparison groupIncentive delay taskVentral striatal activationPG groupMonetary rewardsVentromedial prefrontal cortexSimilar associationImaging studiesFrontostriatal activityLoss anticipationConsistent alterationsActivation changesPrefrontal cortexLevels of impulsivity