The FGF system positively regulates vascular integrity after ischemic injury
Murakami M, Moodie K, Zhuang Z, Ko I, Stan R, Simons M. The FGF system positively regulates vascular integrity after ischemic injury. The FASEB Journal 2006, 20: a636-a636. DOI: 10.1096/fasebj.20.4.a636-b.Peer-Reviewed Original ResearchIschemic injuryFemoral arteryTen-week-old miceVascular integrityEndothelial cellsRight femoral arteryTissue cGMP levelsFemoral artery ligationGrowth factor systemFibroblast growth factor (FGF) systemRat femoral arteryConditional transgenic mouse lineTransgenic mouse lineFGF systemAortic endothelial cellsEndothelial barrier functionBovine aortic endothelial cellsIschemic sideArtery ligationVascular leakageHindlimb ischemiaOld miceIschemic regionCGMP levelsFoot loss