2024
Trend of Controlled Low-Density Lipoprotein Cholesterol in Older Adults With a History of Myocardial Infarction or Stroke
Park D, Jamil Y, Frampton J, Al Damluji A, Nanna M. Trend of Controlled Low-Density Lipoprotein Cholesterol in Older Adults With a History of Myocardial Infarction or Stroke. JACC Advances 2024, 3: 101091. DOI: 10.1016/j.jacadv.2024.101091.Peer-Reviewed Original ResearchAssociation Between Body Mass Index, Testing Performance And Clinical Outcomes In Patients With Stable Chest Pain: Insights From The PRECISE (Prospective Randomized Trial Of The Optimal Evaluation Of Cardiac Symptoms And Revascularization) Trial
Ferencik M, Vemulapalli S, Nanna M, Kelsey M, Mark D, Leipsic J, Ng N, Maurovich-Horvat P, Mullen S, Rogers C, Udelson J, Douglas P. Association Between Body Mass Index, Testing Performance And Clinical Outcomes In Patients With Stable Chest Pain: Insights From The PRECISE (Prospective Randomized Trial Of The Optimal Evaluation Of Cardiac Symptoms And Revascularization) Trial. Journal Of Cardiovascular Computed Tomography 2024, 18: s38. DOI: 10.1016/j.jcct.2024.05.087.Peer-Reviewed Original ResearchRepresentation of Older Adults in the ACC/AHA/SCAI Guideline for Coronary Artery Revascularization
Jamil Y, Sibindi C, Park D, Frampton J, Damluji A, Nanna M. Representation of Older Adults in the ACC/AHA/SCAI Guideline for Coronary Artery Revascularization. JAMA Network Open 2024, 7: e2421547. PMID: 38995647, PMCID: PMC11245718, DOI: 10.1001/jamanetworkopen.2024.21547.Peer-Reviewed Original ResearchPercutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis
Reddy R, Howard J, Jamil Y, Madhavan M, Nanna M, Lansky A, Leon M, Ahmad Y. Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis. Journal Of The American College Of Cardiology 2024, 84: 276-294. PMID: 38986670, DOI: 10.1016/j.jacc.2024.04.051.Peer-Reviewed Original ResearchConceptsRelative riskCardiovascular mortalityMyocardial infarctionMultivessel coronary artery diseaseAll-cause mortalityAdverse cardiac eventsST-segment elevation myocardial infarctionComplete revascularizationCoronary artery diseaseBayesian network meta-analysesMortality reductionA systematic reviewNetwork meta-analysesElevation myocardial infarctionSystematic reviewMeta-analysesCardiac eventsArtery diseasePrimary outcomeNetwork meta-analysisRevascularization strategyMeta-analysisHead-to-head trialsCoronary revascularization strategyAcute kidney injuryApixaban to Prevent Recurrence After Cryptogenic Stroke
Chi K, Nanna M, Nanna M. Apixaban to Prevent Recurrence After Cryptogenic Stroke. JAMA 2024, 331: 1965-1966. PMID: 38739398, DOI: 10.1001/jama.2024.6851.Peer-Reviewed Original ResearchQuality of Life in Older Adults With Stable Ischemic Heart Disease and Diabetes Mellitus: A Post Hoc Analysis of the BARI 2D Trial
Park D, Jamil Y, Moumneh M, Batchelor B W, Nanna M, Damluji A. Quality of Life in Older Adults With Stable Ischemic Heart Disease and Diabetes Mellitus: A Post Hoc Analysis of the BARI 2D Trial. The American Journal Of Cardiology 2024, 223: 58-69. PMID: 38797195, PMCID: PMC11214881, DOI: 10.1016/j.amjcard.2024.05.016.Peer-Reviewed Original ResearchDuke Activity Status IndexOlder adultsYears of follow-upStable ischemic heart diseaseIntensive medical therapyQoL measuresStatus indexIschemic heart diseaseDistress ratingsOlder adult populationOlder adult patientsBARI 2D trialDiabetes mellitusQuality of lifeQuality-of-lifeHeart diseaseMultivariate linear regressionFollow-upMedical therapyAdult populationQoLCognitive impairmentOlder patientsPost hoc analysisChronic total occlusionMachine learning prediction of one-year mortality after percutaneous coronary intervention in acute coronary syndrome patients.
Hosseini K, Behnoush AH, Khalaji A, Etemadi A, Soleimani H, Pasebani Y, Jenab Y, Masoudkabir F, Tajdini M, Mehrani M, Nanna MG. Machine learning prediction of one-year mortality after percutaneous coronary intervention in acute coronary syndrome patients. Int J Cardiol 2024, 409: 132191. PMID: 38777044, DOI: 10.1016/j.ijcard.2024.132191.Peer-Reviewed Original ResearchAssociation Between Frailty and Management and Outcomes of Acute Myocardial Infarction Complicated by Cardiogenic Shock
Jamil Y, Park D, Rao S, Ahmad Y, Sikand N, Bosworth H, Coles T, Damluji A, Nanna M, Samsky M. Association Between Frailty and Management and Outcomes of Acute Myocardial Infarction Complicated by Cardiogenic Shock. JACC Advances 2024, 3: 100949. PMID: 38938859, PMCID: PMC11198471, DOI: 10.1016/j.jacadv.2024.100949.Peer-Reviewed Original ResearchAcute myocardial infarctionAMI-CSIn-hospital outcomesDo-not-resuscitate statusPatients admitted with acute myocardial infarctionOdds of in-hospital mortalitySkilled nursing facilityPrevalence of frailtyProportion of hospitalsAssociated with in-hospital outcomesIn-hospital adverse eventsCompare in-hospital outcomesRisk score cut-offNational Inpatient SampleNursing facilitiesIn-hospital mortalityScore cut-offAssociated with adverse outcomesInpatient SampleFrailtyCardiogenic shockIn-hospital morbidityMyocardial infarction complicationsNonfrail groupOddsSeasonal variations in admissions for atrial fibrillation or atrial flutter in the Northeast and the Midwest regions of the United States
Park D, Bittar-Carlini G, Kumar M, Jamil Y, Nanna M. Seasonal variations in admissions for atrial fibrillation or atrial flutter in the Northeast and the Midwest regions of the United States. Baylor University Medical Center Proceedings 2024, 37: 560-568. PMID: 38910792, PMCID: PMC11188794, DOI: 10.1080/08998280.2024.2346050.Peer-Reviewed Original ResearchCase Volumes and Outcomes Among Early-Career Interventional Cardiologists in the United States
Rymer J, Narcisse D, Chen A, Wojdyla D, Ashley S, Damluji A, Shah B, Nanna M, Swaminathan R, Gutierrez J, Uzendu A, Nelson A, Bethel G, Kearney K, Jones W, Rao S, Doll J. Case Volumes and Outcomes Among Early-Career Interventional Cardiologists in the United States. Journal Of The American College Of Cardiology 2024, 83: 1990-1998. PMID: 38749617, PMCID: PMC11173360, DOI: 10.1016/j.jacc.2024.03.395.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAnnual case volumeNational Cardiovascular Data Registry CathPCI RegistryCase volumeIncreased risk of mortalityBleeding riskRisk of mortalityST-segment elevation myocardial infarctionMedian annual case volumeEarly-careerCertificate databaseCathPCI RegistryInterventional cardiologistsMortality riskElevation myocardial infarctionAmerican BoardIncreased riskSystem databasePredicted riskBleeding outcomesAcute presentationTreated patientsMortality rateProcedural characteristicsCareer statusChronological vs Biological Age in Interventional Cardiology A Comprehensive Approach to Care for Older Adults: JACC Family Series
Damluji A, Nanna M, Rymer J, Kochar A, Lowenstern A, Baron S, Narins C, Alkhouli M. Chronological vs Biological Age in Interventional Cardiology A Comprehensive Approach to Care for Older Adults: JACC Family Series. JACC Cardiovascular Interventions 2024, 17: 961-978. PMID: 38597844, PMCID: PMC11097960, DOI: 10.1016/j.jcin.2024.01.284.Peer-Reviewed Original ResearchConceptsCardiovascular careImprove health outcomesOlder adult populationPatient-centered outcomesBiological ageAge-associated riskAging global populationAge-related riskFamily seriesComplex careHealth outcomesJACC State-of-the-Art ReviewOlder AdultsChronic illnessInfluence eligibilityProcedural adverse eventsStructural heart diseaseClinical focusCareOlder individualsInvasive careAdult populationInterventionCardiovascular diseaseOlder patientsFrailty and In-Hospital Outcomes for Management of Cardiogenic Shock without Acute Myocardial Infarction
Park D, Jamil Y, Ahmad Y, Coles T, Bosworth H, Sikand N, Davila C, Babapour G, Damluji A, Rao S, Nanna M, Samsky M. Frailty and In-Hospital Outcomes for Management of Cardiogenic Shock without Acute Myocardial Infarction. Journal Of Clinical Medicine 2024, 13: 2078. PMID: 38610842, PMCID: PMC11012362, DOI: 10.3390/jcm13072078.Peer-Reviewed Original ResearchDo-not-resuscitate statusOdds of in-hospital mortalitySkilled nursing facilityIn-hospital adverse eventsRelationship of frailtyCompare in-hospital outcomesNon-frail groupRisk score cut-offNational Inpatient SampleAssociated with increased rates of morbidityNursing facilitiesMyocardial infarctionAssociated with increased ratesFrail adultsIn-hospital mortalityIn-hospital outcomesAcute myocardial infarctionFrail groupScore cut-offFrailtyInpatient SampleCardiogenic shockRisk factorsCardiovascular diseaseHospitalAssociation of cardiovascular diseases with cognitive performance in older adults
Park D, Jamil Y, Babapour G, Kim J, Campbell G, Akman Z, Kochar A, Sen S, Samsky M, Sikand N, Frampton J, Damluji A, Nanna M. Association of cardiovascular diseases with cognitive performance in older adults. American Heart Journal 2024, 273: 10-20. PMID: 38575050, PMCID: PMC11162917, DOI: 10.1016/j.ahj.2024.03.016.Peer-Reviewed Original ResearchAnimal Fluency TestOlder adultsCERAD-DRDSST scoresCardiovascular diseaseNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyCongestive heart failureFree of cardiovascular diseaseFluency testCardiovascular disease subtypesNutrition Examination SurveyAssociation of cardiovascular diseaseAnimal Fluency test scoreCognitive performanceLower cognitive performanceCoronary heart diseaseHeart failureCVD subtypesExamination SurveyAssess cognitive performanceAdultsCognitive functionHeart diseaseScoresPERFORMANCE OF THE PROMISE MINIMAL RISK SCORE IN STABLE ANGINA PATIENTS IN THE PROSPECTIVE RANDOMIZED TRIAL OF THE OPTIMAL EVALUATION OF CARDIAC SYMPTOMS AND REVASCULARIZATION (PRECISE) TRIAL
Kelsey M, Nanna M, Vemulapalli S, Yow E, Chiswell K, Ng N, Mark D, Pier K, Huey W, Mullen S, Rogers C, Fordyce C, Udelson J, Douglas P. PERFORMANCE OF THE PROMISE MINIMAL RISK SCORE IN STABLE ANGINA PATIENTS IN THE PROSPECTIVE RANDOMIZED TRIAL OF THE OPTIMAL EVALUATION OF CARDIAC SYMPTOMS AND REVASCULARIZATION (PRECISE) TRIAL. Journal Of The American College Of Cardiology 2024, 83: 1330. DOI: 10.1016/s0735-1097(24)03320-5.Peer-Reviewed Original ResearchUNDERSTANDING THE IMPORTANCE OF AGE IN SELECTING A TESTING STRATEGY FOR STABLE SYMPTOMATIC PATIENTS WITH SUSPECTED CORONARY ARTERY DISEASE: A PRESPECIFIED ANALYSIS FROM THE PRECISE RANDOMIZED TRIAL
Vemmou E, Kelsey M, Vemulapalli S, Mark D, Rogers C, Mullen S, Huey W, Chiswell K, Clare R, Caune A, Yow E, Leipsic J, Byrne R, Ng N, Pier K, Udelson J, Douglas P, Nanna M. UNDERSTANDING THE IMPORTANCE OF AGE IN SELECTING A TESTING STRATEGY FOR STABLE SYMPTOMATIC PATIENTS WITH SUSPECTED CORONARY ARTERY DISEASE: A PRESPECIFIED ANALYSIS FROM THE PRECISE RANDOMIZED TRIAL. Journal Of The American College Of Cardiology 2024, 83: 1183. DOI: 10.1016/s0735-1097(24)03173-5.Peer-Reviewed Original ResearchREPRESENTATION OF OLDER ADULTS IN THE CURRENT ACC/AHA/SCAI GUIDELINE FOR CORONARY ARTERY REVASCULARIZATION
Jamil Y, Sibindi C, Park D, Frampton J, Damluji A, Nanna M. REPRESENTATION OF OLDER ADULTS IN THE CURRENT ACC/AHA/SCAI GUIDELINE FOR CORONARY ARTERY REVASCULARIZATION. Journal Of The American College Of Cardiology 2024, 83: 852. DOI: 10.1016/s0735-1097(24)02842-0.Peer-Reviewed Original ResearchFrailty in the cardiac intensive care unit: assessment and impact
Moumneh M, Jamil Y, Kalra K, Ijaz N, Campbell G, Kochar A, Nanna M, van Diepen S, Damluji A. Frailty in the cardiac intensive care unit: assessment and impact. European Heart Journal Acute Cardiovascular Care 2024, 13: 506-514. PMID: 38525951, PMCID: PMC11214587, DOI: 10.1093/ehjacc/zuae039.Peer-Reviewed Original ResearchCardiac intensive care unitIntensive care unitCardiac intensive care unit admissionCare unitAcute cardiovascular illnessHigher comorbidity burdenAcute cardiovascular conditionsYears of ageOptimal therapyYounger patientsClinical outcomesFrail patientsClinical syndromeComorbidity burdenPhysiological reserveCardiovascular diseasePatientsCardiovascular conditionsGeriatric syndromesCardiovascular illnessFrailtyOlder adultsCognitive functionShorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention
Park D, Hu J, Jamil Y, Kelsey M, Jones W, Frampton J, Kochar A, Aronow W, Damluji A, Nanna M. Shorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention. JAMA Network Open 2024, 7: e244000. PMID: 38546647, PMCID: PMC10979312, DOI: 10.1001/jamanetworkopen.2024.4000.Peer-Reviewed Original ResearchConceptsOlder adultsMonths of DAPTDuration of dual antiplatelet therapySystematic reviewRandomized clinical trialsPercutaneous coronary interventionMeta-analysisPreferred Reporting ItemsAssess data qualityRisk of bleedingDuration of DAPTDual antiplatelet therapyWeb of ScienceMain OutcomesReporting ItemsData extractionAbstracted dataSecondary outcomesRisk ratioAntiplatelet therapyPrimary outcomeCochrane LibraryCoronary interventionReference groupNetwork meta-analysisRole of Cognitive Frailty in Older Adults With Cardiovascular Disease
Ijaz N, Jamil Y, Brown C, Krishnaswami A, Orkaby A, Stimmel M, Gerstenblith G, Nanna M, Damluji A. Role of Cognitive Frailty in Older Adults With Cardiovascular Disease. Journal Of The American Heart Association 2024, 13: e033594. PMID: 38353229, PMCID: PMC11010094, DOI: 10.1161/jaha.123.033594.Peer-Reviewed Original ResearchConceptsCognitive frailtyCardiovascular diseaseDecreased cognitive reserveOlder adult populationCognitive impairmentEvidence of dementiaPresence of cognitive impairmentTargeted intervention studiesSedentary behaviorTobacco usePhysical frailtyOlder adultsGeriatric syndromesIntervention studiesCardiovascular cliniciansFrailtyAdult populationAssociated with poor outcomesCognitive reserveRisk factorsOlder patientsCliniciansPoor outcomeTherapeutic strategiesPathophysiological underpinningsIntravascular Imaging–Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review and Meta‐Analysis of Randomized Trials
Sreenivasan J, Reddy R, Jamil Y, Malik A, Chamie D, Howard J, Nanna M, Mintz G, Maehara A, Ali Z, Moses J, Chen S, Chieffo A, Colombo A, Leon M, Lansky A, Ahmad Y. Intravascular Imaging–Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review and Meta‐Analysis of Randomized Trials. Journal Of The American Heart Association 2024, 13: e031111. PMID: 38214263, PMCID: PMC10926835, DOI: 10.1161/jaha.123.031111.Peer-Reviewed Original ResearchConceptsAdverse cardiac eventsPercutaneous coronary interventionAngiography-guided percutaneous coronary interventionTarget vessel revascularizationTarget-lesion revascularizationCardiac eventsCardiac deathImaging-guided percutaneous coronary interventionWeighted mean follow-up durationMeta-analysisPrimary outcomeMean follow-up durationStent thrombosisMeta-analysis of randomized trialsStudy-level meta-analysisComplex lesion subsetsIntravascular imagingAll-cause deathRandom-effects meta-analysisStandard of careIntention-to-treat principleUpdates of clinical guidelinesMixed-effects meta-regressionComplex percutaneous coronary interventionIntravascular imaging-guided percutaneous coronary intervention