Primary prevention statin therapy in older adults
Nanna M, Abdullah A, Mortensen M, Navar A. Primary prevention statin therapy in older adults. Current Opinion In Cardiology 2022, 38: 11-20. PMID: 36598445, PMCID: PMC9830552, DOI: 10.1097/hco.0000000000001003.Peer-Reviewed Original ResearchConceptsAge 75Older adult populationStatin treatmentRandomized trialsAdult populationPrimary prevention statin therapyOlder adultsAverage lifespan increasesRecent guideline recommendationsACC/AHAOngoing randomized trialsPrevention of morbidityPaucity of evidenceStatin therapyStatin useUSPSTF recommendationsOlder patientsGuideline recommendationsOngoing trialsTreatment recommendationsCardiovascular diseaseTreatment benefitTreatment decisionsGuidelines conflictTrialsChoice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial
Wang SY, Hanna JM, Gongal P, Onuma O, Nanna MG. Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial. American Heart Journal 2022, 254: 30-34. PMID: 35932912, PMCID: PMC10908340, DOI: 10.1016/j.ahj.2022.07.006.Peer-Reviewed Original ResearchConceptsDiastolic hypertensionSystolic hypertensionAntihypertensive agentsSecondary analysisPrevent Heart Attack TrialBroad treatment recommendationsDifferent antihypertensive agentsUse of chlorthalidoneLipid-Lowering TreatmentHeart Attack TrialCoronary heart diseaseCause mortalityPrimary outcomeAttack TrialALLHAT trialHeart diseaseTreatment recommendationsHypertensionPatientsTrialsAntihypertensivesAmlodipineLisinoprilStrokeAgents