2024
Oral anticoagulants or antiplatelets for cryptogenic stroke: a systematic review and meta-analysis
Chi K, Song J, Zarif T, Chiang C, Lee P, Chang Y, Nanna M, Nanna M. Oral anticoagulants or antiplatelets for cryptogenic stroke: a systematic review and meta-analysis. European Heart Journal 2024, 45: ehae666.2309. DOI: 10.1093/eurheartj/ehae666.2309.Peer-Reviewed Original ResearchLeft atrial diameterRelevant randomized controlled trialsPatent foramen ovaleNAVIGATE ESUS trialOral anticoagulantsOral anticoagulant useRecurrent ischemic strokeCryptogenic strokeIschemic strokeMeta-analysisSubgroup analysisESUS patientsHazard ratioSafety of oral anticoagulantsInternational Society of ThrombosisSociety of ThrombosisOptimal antithrombotic strategyAtrial cardiopathyDiagnostic work-upRE-SPECT ESUSElectronic databases of PubMedCryptogenic stroke patientsSources of cardioembolismRandom-effects meta-analysisSystematic reviewMortality effects of beta-blockers on myocardial infarction in patients without reduced ejection fraction or heart failure in the contemporary reperfusion era : a systematic review and meta-analysis
Y K, Lee P, Chowdhury I, Schwartz R, Kang Y, Mangalesh S, Babapour G, Akman Z, Chang Y, Song J, Lessa Y, Damluji A, Nanna M, Nanna M. Mortality effects of beta-blockers on myocardial infarction in patients without reduced ejection fraction or heart failure in the contemporary reperfusion era : a systematic review and meta-analysis. European Heart Journal 2024, 45: ehae666.1640. DOI: 10.1093/eurheartj/ehae666.1640.Peer-Reviewed Original ResearchRandomized controlled trialsReduced ejection fractionBeta-blockersEjection fractionHeart failureMortality benefitReduced EFMeta-regressionEF patientsPreserved EFBB usersReperfusion eraMeta-analysisSubgroup analysisSystematic reviewPost-MIPost-MI careEffect of beta-blockersIncreased all-cause mortalityHistory of HFEvent-free periodAll-cause mortalityTemporal trendsStudy inclusion periodModern randomized controlled trialsPercutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis
Reddy R, Howard J, Jamil Y, Madhavan M, Nanna M, Lansky A, Leon M, Ahmad Y. Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis. Journal Of The American College Of Cardiology 2024, 84: 276-294. PMID: 38986670, DOI: 10.1016/j.jacc.2024.04.051.Peer-Reviewed Original ResearchConceptsRelative riskCardiovascular mortalityMyocardial infarctionMultivessel coronary artery diseaseAll-cause mortalityAdverse cardiac eventsST-segment elevation myocardial infarctionComplete revascularizationCoronary artery diseaseBayesian network meta-analysesMortality reductionA systematic reviewNetwork meta-analysesElevation myocardial infarctionSystematic reviewMeta-analysesCardiac eventsArtery diseasePrimary outcomeNetwork meta-analysisRevascularization strategyMeta-analysisHead-to-head trialsCoronary revascularization strategyAcute kidney injuryShorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention
Park D, Hu J, Jamil Y, Kelsey M, Jones W, Frampton J, Kochar A, Aronow W, Damluji A, Nanna M. Shorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention. JAMA Network Open 2024, 7: e244000. PMID: 38546647, PMCID: PMC10979312, DOI: 10.1001/jamanetworkopen.2024.4000.Peer-Reviewed Original ResearchConceptsOlder adultsMonths of DAPTDuration of dual antiplatelet therapySystematic reviewRandomized clinical trialsPercutaneous coronary interventionMeta-analysisPreferred Reporting ItemsAssess data qualityRisk of bleedingDuration of DAPTDual antiplatelet therapyWeb of ScienceMain OutcomesReporting ItemsData extractionAbstracted dataSecondary outcomesRisk ratioAntiplatelet therapyPrimary outcomeCochrane LibraryCoronary interventionReference groupNetwork meta-analysis
2022
TCT-9 Invasive Strategy Versus Medical Therapy in Older Adults ≥75 Years of Age With Non–ST-Segment Elevation Acute Coronary Syndrome: A Systematic Review and Meta-analysis
Rout A, Garg A, Lohana V, Singh V, Rymer J, Nanna M, Kochar A, Damluji A. TCT-9 Invasive Strategy Versus Medical Therapy in Older Adults ≥75 Years of Age With Non–ST-Segment Elevation Acute Coronary Syndrome: A Systematic Review and Meta-analysis. Journal Of The American College Of Cardiology 2022, 80: b4. DOI: 10.1016/j.jacc.2022.08.017.Peer-Reviewed Original ResearchShortening the duration of dual antiplatelet therapy after percutaneous coronary intervention for acute coronary syndrome: A systematic review and meta-analysis
Park DY, Wang P, An S, Grimshaw AA, Frampton J, Ohman EM, Rao SV, Nanna MG. Shortening the duration of dual antiplatelet therapy after percutaneous coronary intervention for acute coronary syndrome: A systematic review and meta-analysis. American Heart Journal 2022, 251: 101-114. PMID: 35654162, PMCID: PMC10904033, DOI: 10.1016/j.ahj.2022.05.019.Peer-Reviewed Original ResearchConceptsMonths of DAPTHazard ratioIschemic eventsDuration of DAPTSelect patient characteristicsDual antiplatelet therapyAcute coronary syndromeCoronary artery lesionsPercutaneous coronary interventionConfidence intervalsAssociation of outcomesRandom-effects modelComprehensive literature searchMeta-regression analysisMajor bleedingAntiplatelet therapyCoronary syndromeArtery lesionsCoronary interventionControlled TrialsPatient characteristicsPrespecified outcomesGreater proportionSimilar efficacySystematic review
2018
TCT-775 A Systematic Review of Randomized and Non-randomized Studies Comparing Dual Therapy with Triple Therapy in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention
Sullivan A, Nanna M, Rao S, Cantrell S, Gibson C, Verheugt F, Peterson E, Yee M, Kong D. TCT-775 A Systematic Review of Randomized and Non-randomized Studies Comparing Dual Therapy with Triple Therapy in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention. Journal Of The American College Of Cardiology 2018, 72: b309. DOI: 10.1016/j.jacc.2018.08.2005.Peer-Reviewed Original Research