1990
Reduction of myocardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated Fluosol®11Fluosol® (20% Intravascular Perfluorochemical Emulsion) is a registered trademark of The Green Cross Corporation, Osaka, Japan.
Kent K, Cleman M, Cowley M, Forman M, Jaffe C, Kaplan M, King S, Krucoff M, Lassar T, McAuley B, Smith R, Wisdom C, Wohlgelernter D. Reduction of myocardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated Fluosol®11Fluosol® (20% Intravascular Perfluorochemical Emulsion) is a registered trademark of The Green Cross Corporation, Osaka, Japan. The American Journal Of Cardiology 1990, 66: 279-284. PMID: 2195864, DOI: 10.1016/0002-9149(90)90836-p.Peer-Reviewed Original ResearchConceptsOxygen-carrying perfluorochemical emulsionFluosol perfusionAngioplasty patientsMyocardial ischemiaPerfluorochemical emulsionBaseline levelsGlobal left ventricular ejection fractionLeft ventricular ejection fractionPercutaneous transluminal coronary angioplastyRegional wall dysfunctionSevere anginal painTransluminal coronary angioplastyVentricular ejection fractionST-segment changesAnginal painGreen Cross CorporationCoronary angioplastyEjection fractionMulticenter trialRoutine angioplastyVentricular functionBalloon occlusionBalloon deflationPatient populationBalloon inflationMetabolic and functional effects of perfluorocarbon distal perfusion during coronary angioplasty
Young L, Jaffe C, Revkin J, McNulty P, Cleman M. Metabolic and functional effects of perfluorocarbon distal perfusion during coronary angioplasty. The American Journal Of Cardiology 1990, 65: 986-990. PMID: 2327360, DOI: 10.1016/0002-9149(90)91001-m.Peer-Reviewed Original ResearchConceptsGreat cardiac veinDistal perfusionLactate releaseEjection fractionVentricular functionCardiac veinBalloon inflationLeft ventricular ejection fractionDistal coronary perfusionMyocardial lactate metabolismVentricular ejection fractionMyocardial lactate releaseRegional contractile functionNet lactate extractionNet lactate releaseCoronary angioplastyLeft anteriorCoronary perfusionLactate extractionContractile functionPerfusionAngioplastyLactate concentrationLactate metabolismOxygenated perfluorocarbon
1988
Preservation of left ventricular ejection fraction during percutaneous transluminal coronary angioplasty by distal transcatheter coronary perfusion of oxygenated fluosol DA 20%
Jaffe C, Wohlgelernter D, Cabin H, Bowman L, Deckelbaum L, Remetz M, Cleman M. Preservation of left ventricular ejection fraction during percutaneous transluminal coronary angioplasty by distal transcatheter coronary perfusion of oxygenated fluosol DA 20%. American Heart Journal 1988, 115: 1156-1164. PMID: 2967624, DOI: 10.1016/0002-8703(88)90002-6.Peer-Reviewed Original ResearchConceptsVentricular ejection fractionPercutaneous transluminal coronary angioplastyTransluminal coronary angioplastyEjection fractionCoronary perfusionBalloon inflationCoronary angioplastyDistal coronary perfusionLeft ventricular functionDistal coronary arteriesEnd-diastolic volumeEnd-systolic volumeTwo-dimensional echocardiographyFluosol-DA 20Area-length methodOxygenated perfluorocarbon emulsion
1986
Prevention of ischemia during percutaneous transluminal coronary angioplasty by transcatheter infusion of oxygenated Fluosol DA 20%.
Cleman M, Jaffee C, Wohlgelernter D. Prevention of ischemia during percutaneous transluminal coronary angioplasty by transcatheter infusion of oxygenated Fluosol DA 20%. Circulation 1986, 74: 555-562. PMID: 2943533, DOI: 10.1161/01.cir.74.3.555.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyFluosol-DA 20Regional left ventricular dysfunctionLeft ventricular dysfunctionTransluminal coronary angioplastyTranscatheter infusionBalloon inflationVentricular dysfunctionCoronary angioplastyCatheter balloon inflationLeft ventricular reserveSubsequent myocardial ischemiaCoronary blood flowLactate solutionPrevention of ischemiaLonger inflation timesTwo-dimensional echocardiographyRinger's lactate solutionRegional wall motionRegional contractionDilating catheterDistal infusionVentricular reserveIschemic riskIntracoronary infusionOxygenated fluosol DA-20% distal infusion during coronary angioplasty protects myocardial function.
Jaffe C, Wohlgelernter D, Highman H, Cleman M. Oxygenated fluosol DA-20% distal infusion during coronary angioplasty protects myocardial function. Progress In Clinical And Biological Research 1986, 211: 21-7. PMID: 2938192.Peer-Reviewed Original Research