Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality
Gruenbaum BF, Sandhu MRS, Bertasi RAO, Bertasi TGO, Schonwald A, Kurup A, Gruenbaum SE, Freedman IG, Funaro MC, Blumenfeld H, Sanacora G. Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality. Epilepsia 2021, 62: 1041-1056. PMID: 33751566, PMCID: PMC8443164, DOI: 10.1111/epi.16862.Peer-Reviewed Original ResearchConceptsAbsence seizuresMood disordersChildhood epilepsyCommon manifestationInclusion criteriaEffective treatmentGenetic predispositionGreater oddsAnimal modelsAnatomical pathwaysSystematic reviewDepressionShort lossDisordersPatientsBidirectional relationshipSeizuresCurrent literatureAnxietySocial impairmentFurther researchReviewEpilepsyStrong correlationImpairment