1992
The importance of nasal resistance in obstructive sleep apnea syndrome.
Kerr P, Millar T, Buckle P, Kryger M. The importance of nasal resistance in obstructive sleep apnea syndrome. Journal Of Otolaryngology 1992, 21: 189-95. PMID: 1404570.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeUpper airway collapseSleep apnea syndromeNasal resistanceOSAS patientsApnea syndromeAirway collapseAmount of apneaArousals/hourChronic nasal obstructionNasal airflow resistanceBaseline data collectionNocturnal oxygenationOSAS populationTopical vasoconstrictorOSAS severityNasal obstructionClinical evidenceNocturnal polysomnographyPSG studiesSubjective improvementPosterior rhinomanometryElevated nasal resistanceConditions of baselineSleep architecture
1985
Sleep and Respiration: A Postscript
Kryger M, White D, Zwillich C, Robinson R, Guilleminault C. Sleep and Respiration: A Postscript. Clinics In Chest Medicine 1985, 6: 713-718. PMID: 3853480, DOI: 10.1016/s0272-5231(21)00407-x.Chapters
1981
Upper Airway Obstruction
Acres J, Kryger M. Upper Airway Obstruction. CHEST Journal 1981, 80: 207-211. PMID: 7249767, DOI: 10.1378/chest.80.2.207.Peer-Reviewed Original ResearchSleep Disorders in Chronic Airflow Obstruction
Fleetham J, Kryger M. Sleep Disorders in Chronic Airflow Obstruction. Medical Clinics Of North America 1981, 65: 549-561. PMID: 7017303, DOI: 10.1016/s0025-7125(16)31513-9.Peer-Reviewed Original ResearchMeSH KeywordsAirway ObstructionBlood PressureHumansHypertension, PulmonaryPostureSleep Apnea SyndromesSleep Wake DisordersSleep, REMConceptsChronic airflow obstructionAirflow obstructionPulmonary hypertensionCardiac arrhythmiasLess rapid eye movement sleepRapid eye movement (REM) sleepSecondary pulmonary hypertensionNocturnal oxygen therapyGas exchange abnormalitiesSleep apnea syndromeEye movement sleepSleep stage changesApnea syndromeOxygen therapyPhysiologic disturbancesMovement sleepSleep disordersSleep profilesPatientsObstructionSleepHypertensionArrhythmiasStage changesSyndrome
1980
Sleep apnea in acromegaly
Mezon B, West P, Maclean J, Kryger M. Sleep apnea in acromegaly. The American Journal Of Medicine 1980, 69: 615-623. PMID: 7424949, DOI: 10.1016/0002-9343(80)90477-5.Peer-Reviewed Original ResearchMeSH KeywordsAcromegalyAirway ObstructionHumansMacroglossiaMaleMiddle AgedSleep Apnea SyndromesTracheotomyConceptsUpper airway obstructionSleep apnea syndromeAirway obstructionApnea syndromeSomnolent patientsSevere hypoxemiaPharyngeal airwayUpper airwayNormal sleepLarge tonguePatientsAcromegalyObstructionAirwaySyndromeSleepPeriodic obstructionTongueHypoxemiaSomnolenceTracheostomyApneaEndoscopyLarynxPharynx
1976
Effect of Meperidine on Occlusion Pressure Responses to Hypercapnia and Hypoxia with and without External Inspiratory Resistance1–3
Kryger M, Yacoub O, Dosman J, Macklem P, Anthonisen N. Effect of Meperidine on Occlusion Pressure Responses to Hypercapnia and Hypoxia with and without External Inspiratory Resistance1–3. American Journal Of Respiratory And Critical Care Medicine 1976, 114: 333-40. PMID: 973724, DOI: 10.1164/arrd.1976.114.2.333.Peer-Reviewed Original ResearchMeSH KeywordsAdultAirway ObstructionAirway ResistanceHumansHypercapniaHypoxiaLungMaleMeperidineRespirationRespiratory CenterVentilation-Perfusion RatioConceptsInspiratory resistanceNormal subjectsOcclusion pressure responsesInspiratory motor outputEffect of meperidineOral meperidineVentilatory responseAcute increaseInspiratory effortClosed airwayMeperidineHypercapniaProgressive hypoxiaMotor outputMore depressionHypoxiaHypoxic responsePressure responseP0.1Combination of resistanceSubjectsResponseAirwayDiagnosis of obstruction of the upper and central airways
Kryger M, Bode F, Antic R, Anthonisen N. Diagnosis of obstruction of the upper and central airways. The American Journal Of Medicine 1976, 61: 85-93. PMID: 779469, DOI: 10.1016/0002-9343(76)90048-6.Peer-Reviewed Original ResearchMeSH KeywordsAirway ObstructionAirway ResistanceApneaBronchiectasisDiagnosis, DifferentialFemaleForced Expiratory VolumeHumansMaleMiddle AgedObesityPulmonary Heart DiseasePulmonary VentilationRadiographyResidual VolumeRespiratory System AbnormalitiesSleep Wake DisordersTracheal DiseasesTracheal NeoplasmsVital CapacityConceptsUpper airway obstructionAirway obstructionSleep deprivation syndromeFlow-volume loopsDiagnosis of obstructionMethods of diagnosisSuch patientsPhysical examinationUpper airwayCentral airwaysCorrect diagnosisDeprivation syndromePhysiologic testsCharacteristic historyObstructionPatientsDiagnosisAirwayInstructive caseSyndromeSleep
1974
The sleep deprivation syndrome of the obese patient A problem of periodic nocturnal upper airway obstruction
Kryger M, Quesney L, Holder D, Gloor P, MacLeod P. The sleep deprivation syndrome of the obese patient A problem of periodic nocturnal upper airway obstruction. The American Journal Of Medicine 1974, 56: 531-539. PMID: 4818419, DOI: 10.1016/0002-9343(74)90485-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultAirway ObstructionBradycardiaHumansMaleObesitySleep DeprivationSleep Wake DisordersTracheotomyUrinary IncontinenceConceptsUpper airway obstructionSleep deprivation syndromeAirway obstructionUrinary incontinenceDeprivation syndromeNocturnal upper airway obstructionObese menObese patientsPickwickian syndromeUpper airwayVentilatory responseSyndromeObstructionFat depositionArousal patternsIncontinenceSomnolenceBradycardiaSuch findingsTracheostomyAirwayPatientsPathophysiologySleep
1972
Gas diffusion across collateral channels.
Hogg W, Brunton J, Kryger M, Brown R, Macklem P. Gas diffusion across collateral channels. Journal Of Applied Physiology 1972, 33: 568-575. PMID: 4635918, DOI: 10.1152/jappl.1972.33.5.568.Peer-Reviewed Original Research