2009
Expenditure on Health Care in Obese Women with and without Sleep Apnea
Banno K, Ramsey C, Walld R, Kryger MH. Expenditure on Health Care in Obese Women with and without Sleep Apnea. Sleep 2009, 32: 247-252. PMID: 19238812, PMCID: PMC2635589, DOI: 10.1093/sleep/32.2.247.Peer-Reviewed Original ResearchConceptsNormal-weight controlsObese controlsObese womenOSAS casesWeight controlPhysician feesPhysician visitsTertiary university-based medical centerHealth servicesUniversity-based medical centerAge-matched womenEffect of obesityRetrospective observational studyTreatment of OSAOverall medical costsHealth care utilizationMore health servicesGreater financial burdenHealth care expendituresOSA casesCare utilizationSleep apneaObservational studyMedical CenterGeneral population
2008
Association of Sleep Apnea Severity and Obesity with Insulin Resistance, C-Reactive Protein, and Leptin Levels in Male Patients with Obstructive Sleep Apnea
Kapsimalis F, Varouchakis G, Manousaki A, Daskas S, Nikita D, Kryger M, Gourgoulianis K. Association of Sleep Apnea Severity and Obesity with Insulin Resistance, C-Reactive Protein, and Leptin Levels in Male Patients with Obstructive Sleep Apnea. Lung 2008, 186: 209-217. PMID: 18365276, DOI: 10.1007/s00408-008-9082-x.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeSleep apnea severityObstructive sleep apneaNon-OSA groupBody mass indexModerate OSAS groupCRP levelsInsulin resistanceApnea severityOSAS groupMale patientsLeptin levelsSleep apneaSevere obstructive sleep apnea syndromeHomeostasis model assessment methodSevere sleep apneaSevere OSAS groupSleep apnea syndromeC-reactive proteinTotal sleep timeNocturnal hypoxemiaApnea syndromeModel assessment methodHip ratioMass indexAssessment and Management of Patients with Obesity Hypoventilation Syndrome
Mokhlesi B, Kryger MH, Grunstein RR. Assessment and Management of Patients with Obesity Hypoventilation Syndrome. Annals Of The American Thoracic Society 2008, 5: 218-225. PMID: 18250215, PMCID: PMC2645254, DOI: 10.1513/pats.200708-122mg.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAdultAlgorithmsBody Mass IndexHumansObesity Hypoventilation SyndromePrevalenceRisk FactorsConceptsObesity hypoventilation syndromeSleep-disordered breathingHypoventilation syndromeManagement of patientsAvailable treatment modalitiesRelated health care expendituresSerious cardiovascular diseaseHealth care expensesHealth care expendituresDaytime hypercapniaEucapnic patientsSignificant lungClinical characteristicsObese patientsSignificant morbidityEarly mortalityTreatment modalitiesEarly recognitionExtreme obesityCardiovascular diseaseHigh burdenEffective treatmentHigh riskHigh indexClinical practice
2006
Healthcare Utilization in Women with Obstructive Sleep Apnea Syndrome 2 Years After Diagnosis and Treatment
Banno K, Manfreda J, Walld R, Delaive K, Kryger MH. Healthcare Utilization in Women with Obstructive Sleep Apnea Syndrome 2 Years After Diagnosis and Treatment. Sleep 2006, 29: 1307-1311. PMID: 17068984, DOI: 10.1093/sleep/29.10.1307.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeContinuous positive airway pressureClinic visitsHealthcare utilizationWeight lossTertiary university-based medical centerRetrospective observational cohort studyEntire groupUniversity-based medical centerTreatment-compliant patientsObservational cohort studyPositive airway pressureSleep apnea syndromeAirway pressureCohort studyCompliant patientsApnea syndromePhysician claimsMedical CenterWL groupGeneral populationPatientsDiagnosisVisitsWomenGender differences on polysomnographic findings in Greek subjects with obstructive sleep apnea syndrome
Vagiakis E, Kapsimalis F, Lagogianni I, Perraki H, Minaritzoglou A, Alexandropoulou K, Roussos C, Kryger M. Gender differences on polysomnographic findings in Greek subjects with obstructive sleep apnea syndrome. Sleep Medicine 2006, 7: 424-430. PMID: 16740405, DOI: 10.1016/j.sleep.2005.12.014.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeApnea-hypopnea indexBody mass indexSleep apnea syndromeMale patientsApnea syndromeFemale patientsOnset latencyMean apnea-hypopnea indexSleep apnea hypopnea indexHigher apnea-hypopnea indexNon-rapid eye movement sleepSleep disorders centerREM onset latencyEye movement sleepAthens Medical SchoolPercent of menSleep efficiency indexTotal sleep timeGreek subjectsAspects of sleepSleep onset latencyNorth American clinicsEvangelismos HospitalNREM-AHIHyperthyroidism in a patient referred for an assessment of obstructive sleep apnea syndrome
Banno K, Okamura K, Kryger MH. Hyperthyroidism in a patient referred for an assessment of obstructive sleep apnea syndrome. Sleep Medicine 2006, 7: 195-196. PMID: 16458602, DOI: 10.1016/j.sleep.2005.09.001.Peer-Reviewed Original Research
2005
Increasing obesity trends in patients with sleep-disordered breathing referred to a sleep disorders center.
Banno K, Walld R, Kryger MH. Increasing obesity trends in patients with sleep-disordered breathing referred to a sleep disorders center. Journal Of Clinical Sleep Medicine 2005, 1: 364-6. PMID: 17564402, DOI: 10.5664/jcsm.26362.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersBody mass indexSleep disorders centerMean body mass indexDisorders CenterBMI unitsObesity trendsSleep-disordered breathingPrevalence of obesityTime of referralYear of referralNumber of patientsMale patientsFemale patientsMass indexBreathing disordersMean ageNew patientsPatientsSignificant positive correlationReferralWomenObesityRegression analysisSexDifferences between Men and Women in the Clinical Presentation of Patients Diagnosed with Obstructive Sleep Apnea Syndrome
Shepertycky M, Banno K, Kryger MH. Differences between Men and Women in the Clinical Presentation of Patients Diagnosed with Obstructive Sleep Apnea Syndrome. Sleep 2005, 28: 309-314. PMID: 16173651, DOI: 10.1093/sleep/28.3.309.Peer-Reviewed Original ResearchMeSH KeywordsAdultBody Mass IndexFemaleHumansMaleMiddle AgedObesityRetrospective StudiesSex FactorsSleep Apnea, ObstructiveSleep StagesConceptsEpworth Sleepiness Scale scoreApnea-hypopnea indexBody mass indexClinical presentationMass indexObstructive sleep apnea syndrome (OSA) resultsTertiary university-based medical centerScale scoreRetrospective chart review analysisObstructive sleep apnea syndromeUniversity-based medical centerLaboratory polysomnographic studiesMain presenting symptomChart review analysisUpper airway anatomySleep apnea syndromeHistory of depressionGender-related differencesLess alcohol consumptionPolysomnographic findingsPresenting symptomApnea syndromeHypothyroid diseasePolysomnographic studyPrimary complaint
2002
Cardiovascular medication use in patients with undiagnosed obstructive sleep apnoea
Otake K, Delaive K, Walld R, Manfreda J, Kryger M. Cardiovascular medication use in patients with undiagnosed obstructive sleep apnoea. Thorax 2002, 57: 417. PMID: 11978918, PMCID: PMC1746332, DOI: 10.1136/thorax.57.5.417.Peer-Reviewed Original ResearchConceptsMore daily dosesCardiovascular diseaseSystemic hypertensionMedication usePrescribed medicationsDaily dosesMore prescriptionsOdds ratioSleep apnoea/hypopnoea syndromeUndiagnosed obstructive sleep apnoeaObstructive sleep apnoeaCardiovascular medication useCongestive heart failureUse of medicationsGeneral population controlsOSAS casesMore medicationsSecondary preventionAngina pectorisHeart failureSleep apnoeaMedication costsSuch medicationsMyocardial infarctionOSAS diagnosisWhat Are Obstructive Sleep Apnea Patients Being Treated for Prior to This Diagnosis?
Smith R, Ronald J, Delaive K, Walld R, Manfreda J, Kryger MH. What Are Obstructive Sleep Apnea Patients Being Treated for Prior to This Diagnosis? CHEST Journal 2002, 121: 164-172. PMID: 11796446, DOI: 10.1378/chest.121.1.164.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeBody mass indexChronic obstructive airways diseaseObstructive airways diseaseHealth care utilizationSleep apnea patientsControl subjectsApnea patientsAirway diseaseOSAS patientsCardiovascular diseaseObstructive sleep apnea patientsHealth care utilization measuresApnea-hypopnea indexCongestive heart failureEffect of obesityIschemic heart diseaseSleep apnea syndromeDegree of hypoxemiaSignificant independent predictorsLogistic regression analysisCertain cardiovascular disordersHealth care resourcesRegression analysisApnea syndrome
1999
Health Care Utilization in Males with Obstructive Sleep Apnea Syndrome Two Years After Diagnosis and Treatment
Bahammam A, Delaive K, Ronald J, Manfreda J, Roos L, Kryger M. Health Care Utilization in Males with Obstructive Sleep Apnea Syndrome Two Years After Diagnosis and Treatment. Sleep 1999, 22: 740-747. PMID: 10505819, DOI: 10.1093/sleep/22.6.740.Peer-Reviewed Original ResearchConceptsOSA patientsGeneral populationProspective observational cohort studyObservational cohort studySubgroup of patientsSleep disorders centerTreatment of patientsTwo yearsOSAS groupCohort studyPAT groupControl subjectsDisorders CenterPhysician claimsPatientsUtilization dataOne-yearDiagnosisYears one yearTreatmentYearsCanadian provincesOSASGroupHospital