2007
Sleep apnea: Clinical investigations in humans
Banno K, Kryger MH. Sleep apnea: Clinical investigations in humans. Sleep Medicine 2007, 8: 400-426. PMID: 17478121, DOI: 10.1016/j.sleep.2007.03.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsObstructive sleep apnea syndromeCentral sleep apnea syndromeContinuous positive airway pressureSleep apnea syndromeApnea syndromeApneic episodesTreatment of OSASDiagnosis of SASUpper airway obstructionPositive airway pressureMuscles of respirationCessation of breathingCentral nervous systemAirway obstructionAirway pressureHeart failureOral appliancesRespiratory driveImpaired qualityAbnormal breathingSubjective symptomsDaytime sleepinessCommon disorderMetabolic dysfunctionSleep disruption
1994
Why Should Sleep Apnea Be Diagnosed and Treated?
Yamashiro Y, Kryger M. Why Should Sleep Apnea Be Diagnosed and Treated? Clinical Pulmonary Medicine 1994, 1: 250-259. DOI: 10.1097/00045413-199407000-00007.Peer-Reviewed Original ResearchNasal continuous positive airway pressureObstructive sleep apneaSevere sequelaeRepetitive upper airway obstructionsContinuous positive airway pressureUpper airway obstructionPositive airway pressureTreatment of choiceGoal of treatmentPrimary pathophysiologic eventEffect of treatmentAirway obstructionAirway pressureSevere complicationsPatients' qualitySleep apneaMultisystem dysfunctionPathophysiologic eventsCommon disorderUndiagnosed patientsSevere casesSequelaePatient's lifeApneaPatients
1980
Sleep apnea in acromegaly
Mezon B, West P, Maclean J, Kryger M. Sleep apnea in acromegaly. The American Journal Of Medicine 1980, 69: 615-623. PMID: 7424949, DOI: 10.1016/0002-9343(80)90477-5.Peer-Reviewed Original ResearchConceptsUpper airway obstructionSleep apnea syndromeAirway obstructionApnea syndromeSomnolent patientsSevere hypoxemiaPharyngeal airwayUpper airwayNormal sleepLarge tonguePatientsAcromegalyObstructionAirwaySyndromeSleepPeriodic obstructionTongueHypoxemiaSomnolenceTracheostomyApneaEndoscopyLarynxPharynx
1976
Diagnosis of obstruction of the upper and central airways
Kryger M, Bode F, Antic R, Anthonisen N. Diagnosis of obstruction of the upper and central airways. The American Journal Of Medicine 1976, 61: 85-93. PMID: 779469, DOI: 10.1016/0002-9343(76)90048-6.Peer-Reviewed Original ResearchMeSH KeywordsAirway ObstructionAirway ResistanceApneaBronchiectasisDiagnosis, DifferentialFemaleForced Expiratory VolumeHumansMaleMiddle AgedObesityPulmonary Heart DiseasePulmonary VentilationRadiographyResidual VolumeRespiratory System AbnormalitiesSleep Wake DisordersTracheal DiseasesTracheal NeoplasmsVital CapacityConceptsUpper airway obstructionAirway obstructionSleep deprivation syndromeFlow-volume loopsDiagnosis of obstructionMethods of diagnosisSuch patientsPhysical examinationUpper airwayCentral airwaysCorrect diagnosisDeprivation syndromePhysiologic testsCharacteristic historyObstructionPatientsDiagnosisAirwayInstructive caseSyndromeSleep
1974
The sleep deprivation syndrome of the obese patient A problem of periodic nocturnal upper airway obstruction
Kryger M, Quesney L, Holder D, Gloor P, MacLeod P. The sleep deprivation syndrome of the obese patient A problem of periodic nocturnal upper airway obstruction. The American Journal Of Medicine 1974, 56: 531-539. PMID: 4818419, DOI: 10.1016/0002-9343(74)90485-9.Peer-Reviewed Original ResearchConceptsUpper airway obstructionSleep deprivation syndromeAirway obstructionUrinary incontinenceDeprivation syndromeNocturnal upper airway obstructionObese menObese patientsPickwickian syndromeUpper airwayVentilatory responseSyndromeObstructionFat depositionArousal patternsIncontinenceSomnolenceBradycardiaSuch findingsTracheostomyAirwayPatientsPathophysiologySleep