2005
Auto-Titrating Continuous Positive Airway Pressure for Heart Failure Patients With Cheyne-Stokes Respiration and Central Sleep Apnea
Banno K, Okamura K, Kryger MH. Auto-Titrating Continuous Positive Airway Pressure for Heart Failure Patients With Cheyne-Stokes Respiration and Central Sleep Apnea. Circulation Journal 2005, 69: 1295. PMID: 16200689, DOI: 10.1253/circj.69.1295.Peer-Reviewed Original Research
1994
Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure
Steens R, Millar T, Xiaoling S, Biberdorf D, Buckle P, Ahmed M, Kryger M. Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure. Sleep 1994, 17: 61-68. PMID: 8191204, DOI: 10.1093/sleep/17.1.61.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureInhalation of CO2Heart failureSleep timeNocturnal arterial oxygen desaturationNight polysomnographic studiesArterial oxygen desaturationMovement sleep timeTotal sleep timeApnea indexOxygen desaturationMost patientsPolysomnographic studySleep latencySleep disruptionClinical significanceCardiac diseaseSleep structurePatientsNeurological diseasesNight 3Virtual abolitionShort duration
1993
Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration
Biberdorf D, Steens R, Millar T, Kryger M. Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration. Sleep 1993, 16: 529-538. PMID: 8235237, DOI: 10.1093/sleep/16.6.529.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureTotal sleep timePercentage of TSTApnea/hypopnea indexOxygen saturationTotal wake timeEffects of temazepamHeart failureSleep architectureDouble-blind crossover trialSevere congestive heart failureOvernight oxygen saturationStage 1 sleepHours of sleepSleep stage proportionsCHF patientsHypopnea indexMale patientsDaytime somnolenceCrossover trialSignificant changesFrequent arousalsDaytime alertnessSleep time
1992
The Effect of Short-term Nasal CPAP on Cheyne-Stokes Respiration in Congestive Heart Failure
Buckle P, Millar T, Kryger M. The Effect of Short-term Nasal CPAP on Cheyne-Stokes Respiration in Congestive Heart Failure. CHEST Journal 1992, 102: 31-35. PMID: 1623779, DOI: 10.1378/chest.102.1.31.Peer-Reviewed Original ResearchConceptsCongestive heart failureCheyne-Stokes respirationMultiple sleep latency testNasal CPAPSleep qualityNocturnal oxygenationHeart failureTreatment nightsDaytime arterial blood gas valuesArterial blood gas valuesNasal CPAP therapyNYHA class 3Sleep latency testBlood gas valuesShort-term treatmentSignificant differencesAge 54.1CPAP therapyMale patientsFull polysomnographyDaytime sleepinessLatency testCPAPPatientsGas valuesShort Technical Note: Quantification of Periodic Breathing: Preliminary Studies
Millar T, Hanly P, Kryger M. Short Technical Note: Quantification of Periodic Breathing: Preliminary Studies. Sleep 1992, 15: 364-370. PMID: 1519013, DOI: 10.1093/sleep/15.4.364.Peer-Reviewed Original ResearchConceptsApnea/hypopnea indexPeriodic breathingHypopnea indexBreathing patternPattern abnormalitiesHeart failure patientsCheyne-Stokes respirationNight sleep studiesApnea indexFailure patientsPatient populationIndividual patientsSleep studiesPeriodicity indexSleep laboratoryBreathingPatientsAbnormalitiesSleepSpectral analytic techniquesFuture studiesHigh correlationPreliminary studyIndexApnea
1991
Cheyne-Stokes respiration: Stability of interacting systems in heart failure.
Kryger M, Millar T. Cheyne-Stokes respiration: Stability of interacting systems in heart failure. Chaos An Interdisciplinary Journal Of Nonlinear Science 1991, 1: 265-269. PMID: 12779924, DOI: 10.1063/1.165839.Peer-Reviewed Original Research
1989
The effect of oxygen on respiration and sleep in patients with congestive heart failure.
Hanly P, Millar T, Steljes D, Baert R, Frais M, Kryger M. The effect of oxygen on respiration and sleep in patients with congestive heart failure. Annals Of Internal Medicine 1989, 111: 777-82. PMID: 2817624, DOI: 10.7326/0003-4819-111-10-777.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureHeart failureTotal sleep timeOxygen therapySleep timeStage 1 NREM sleepPlacebo-controlled crossover studyLow-flow oxygenNocturnal oxygen saturationNocturnal oxygen therapyOutpatient cardiology clinicApnea-hypopnea indexNumber of arousalsStage 1 sleepStage 2 sleepSlow-wave sleepHyperpneic phaseNocturnal hypoxemiaSleep hypoxemiaMale patientsNasal cannulaeCardiology clinicCrossover studyRespiration and Abnormal Sleep in Patients with Congestive Heart Failure
Hanly B, Millar T, Steljes D, Boert R, Frais M, Kryger M. Respiration and Abnormal Sleep in Patients with Congestive Heart Failure. CHEST Journal 1989, 96: 480-488. PMID: 2766808, DOI: 10.1378/chest.96.3.480.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureStage 2 NREM sleepSlow-wave sleepSleep stage changesNREM sleepHyperpneic phaseHeart failureREM sleepAwake arterial oxygen saturationStable congestive heart failureSevere congestive heart failureStage 1Mean minimum SaO2Outcomes of patientsNumber of arousalsArterial oxygen saturationStage 1 sleepMinimum SaO2Severe hypoxemiaArterial oxygenationSignificant hypoxemiaClinical statusMean durationAbnormal sleep