2022
Plasma Menthol Glucuronide as a Biomarker for the Behavioral Effects of Menthol and Nicotine in Humans
Gueorguieva R, Schwartz EKC, MacLean RR, DeVito EE, Eid T, Wu R, O’Malley S, Sofuoglu M. Plasma Menthol Glucuronide as a Biomarker for the Behavioral Effects of Menthol and Nicotine in Humans. Frontiers In Pharmacology 2022, 13: 844824. PMID: 35431934, PMCID: PMC9009207, DOI: 10.3389/fphar.2022.844824.Peer-Reviewed Original ResearchSubjective drug effectsPlasma Mg concentrationHeart rateDrug effectsIntravenous deliveryNon-menthol cigarette smokersPlacebo-controlled studyTest sessionsCigarette smokersMenthol smokersAcute effectsIntravenous nicotineGlucuronide concentrationsMAIN OUTCOMENicotine infusionMenthol glucuronideSecondary analysisPlasma MgE-cigarettesBehavioral effectsMenthol exposureNicotineSmokersPhysiological effectsE-liquids
2015
The effects of alcohol-containing e-cigarettes on young adult smokers
Valentine GW, Jatlow PI, Coffman M, Nadim H, Gueorguieva R, Sofuoglu M. The effects of alcohol-containing e-cigarettes on young adult smokers. Drug And Alcohol Dependence 2015, 159: 272-276. PMID: 26778759, PMCID: PMC5171208, DOI: 10.1016/j.drugalcdep.2015.12.011.Peer-Reviewed Original ResearchConceptsSubjective drug effectsE-cigarettesDrug effectsAlcohol metabolitesPlasma alcohol levelsUrine ethyl glucuronideLong-term health risksYoung adult smokersAlcohol conditionE-liquidsAcute safetyAdult smokersNicotine intakeAcute changesSafety dataNicotine addictionCrossover designBiochemical measuresAlcohol levelsPsychomotor performanceElectronic cigarettesDexterity testVulnerable populationsEthyl glucuronideMotor performance