Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
Stewart R, King M, Horsley V. Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease. Stem Cell Biology And Regenerative Medicine 2018, 263-292. DOI: 10.1007/978-3-319-16769-5_11.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNuclear laminaIntegral inner nuclear membrane proteinsInner nuclear membrane proteinSkin developmentMechanical signalsNuclear membrane proteinsInner nuclear membraneIntegration of biochemicalGenome integrityNuclear peripheryTranscriptional outputNuclear laminsAssociated chromatinMembrane proteinsNuclear interiorTissue-level mechanicsGene expressionNuclear membraneSkin homeostasisKeratinocyte differentiationMechanical inputChromatinLaminsLaminaProteinThe Molecular Composition and Function of the Nuclear Periphery and Its Impact on the Genome
Lusk C, King M. The Molecular Composition and Function of the Nuclear Periphery and Its Impact on the Genome. 2018, 35-62. DOI: 10.1007/978-3-319-71614-5_2.Peer-Reviewed Original ResearchNuclear peripheryNuclear subcompartmentsIntegral inner nuclear membrane proteinsInner nuclear membrane proteinSpecific genic regionsRepressive histone marksNuclear membrane proteinsGene-poor chromatinModern genomic analysesGenome stabilityHistone marksNuclear architectureGenic regionsTranscriptional outputNuclear laminsGene positionMembrane proteinsGenomic analysisDevelopmental inputsMolecular insightsMolecular componentsGenomeModel systemMolecular compositionCurrent understanding