2014
A Role for Nuclear Envelope Bridging Complexes in Homology-Directed Repair
Swartz RK, Rodriguez EC, King MC. A Role for Nuclear Envelope Bridging Complexes in Homology-Directed Repair. Molecular Biology Of The Cell 2014, 25: mbc.e13-10-0569. PMID: 24943839, PMCID: PMC4142617, DOI: 10.1091/mbc.e13-10-0569.Peer-Reviewed Original ResearchConceptsDNA double-strand breaksHomology-directed repairRepair of DSBsNumber of genesDouble-strand breaksSame gene productCytoskeleton (LINC) complexLINC complexGenome instabilityATR kinaseGene conversionKms1DSB resectionGene productsDepolymerization of microtubulesCell cycleCytoplasmic microtubulesG2 phaseDNA damageSad1MicrotubulesComplexesNucleoskeletonMTO1Cytoskeleton
2008
A Network of Nuclear Envelope Membrane Proteins Linking Centromeres to Microtubules
King MC, Drivas TG, Blobel G. A Network of Nuclear Envelope Membrane Proteins Linking Centromeres to Microtubules. Cell 2008, 134: 427-438. PMID: 18692466, PMCID: PMC2617791, DOI: 10.1016/j.cell.2008.06.022.Peer-Reviewed Original ResearchConceptsSUN-KASH complexesNuclear membrane proteinsMembrane proteinsIntegral inner nuclear membrane proteinsSUN domain protein Sad1Nuclear envelopeSpindle pole body componentInner nuclear membrane proteinFission yeast S. pombeOuter nuclear membrane proteinsCytoplasmic microtubulesYeast S. pombeMicrotubule-dependent forcesNuclear envelope membranesCentromeric DNAS. pombeCentromeric heterochromatinHeterochromatic regionsEnvelope membraneIMA1MicrotubulesSad1HeterochromatinProteinNuclear heterochromatin