2021
Blood virosphere in febrile Tanzanian children
Cordey S, Laubscher F, Hartley M, Junier T, Keitel K, Docquier M, Guex N, Iseli C, Vieille G, Le Mercier P, Gleizes A, Samaka J, Mlaganile T, Kagoro F, Masimba J, Said Z, Temba H, Elbanna G, Tapparel C, Zanella M, Xenarios I, Fellay J, D’Acremont V, Kaiser L. Blood virosphere in febrile Tanzanian children. Emerging Microbes & Infections 2021, 10: 982-993. PMID: 33929935, PMCID: PMC8171259, DOI: 10.1080/22221751.2021.1925161.Peer-Reviewed Original ResearchConceptsInfection/diseaseBlood viromeMetagenomic next-generation sequencingAcute febrile illnessLow-resource clinical settingsAvailable diagnostic toolsFebrile childrenFebrile illnessPediatric populationOutpatient departmentRoutine screeningTanzanian childrenViral infectionPotential viral originViral variantsClinical settingOne-yearDetected virusNext-generation sequencingDar es SalaamDiagnostic toolCausal virusVirusViral originDisease
2016
Use of Peripheral Health Units in Low-Transmission Ebola Virus Disease Surveillance
Young A, Connolly A, Hoar A, Mancuso B, Esplana J, Kaur G, Fisher L, Hartley M, Tran A. Use of Peripheral Health Units in Low-Transmission Ebola Virus Disease Surveillance. Online Journal Of Public Health Informatics 2016, 8: e177. PMCID: PMC4854600, DOI: 10.5210/ojphi.v8i1.6596.Peer-Reviewed Original ResearchEbola virus diseaseEbola Virus Disease SurveillanceMalaria-endemic areasPeripheral health unitsEbola treatment centersEVD casesSymptom recordingMalaria prevalenceCase burdenHealth unitsSuspect casesTreatment centersSurveillance strategiesPort Loko DistrictDisease surveillanceVirus diseaseSurveillance systemSierra LeoneNumber of alertsPatientsLive alertsMalariaPrevalenceDisease
2013
The therapeutic potential of immune cross‐talk in leishmaniasis
Hartley M, Kohl K, Ronet C, Fasel N. The therapeutic potential of immune cross‐talk in leishmaniasis. Clinical Microbiology And Infection 2013, 19: 119-130. PMID: 23398405, DOI: 10.1111/1469-0691.12095.Peer-Reviewed Original ResearchConceptsMetastatic leishmaniasisCutaneous leishmaniasisLeishmania parasitesSelf-healing lesionsProtozoan parasitic diseaseEffective antileishmanial drugsSpecies of LeishmaniaDestructive lesionsImmune homeostasisCurrent treatmentTherapeutic strategiesImmune pathwaysNew drug targetsTherapeutic potentialParasitic diseasesAntileishmanial drugsLeishmaniasisLesionsPrevalent formDiseaseDrug targetsRNA virusesTreatmentVariable effectsParasites
2012
Backseat drivers: the hidden influence of microbial viruses on disease
Hartley M, Ronet C, Fasel N. Backseat drivers: the hidden influence of microbial viruses on disease. Current Opinion In Microbiology 2012, 15: 538-545. PMID: 22694933, DOI: 10.1016/j.mib.2012.05.011.Peer-Reviewed Original ResearchConceptsImportant clinical considerationsMicrobial virusesLeishmania virusDisease processClinical considerationsDiagnostic biomarkersTherapeutic interventionsViral replicationMolecular targetsVirusDiseaseViral hostHuman pathogensHuman diseasesFitness factorsPathogensPathogenesisPrevalenceIncidenceBiomarkers