2023
Rapid antimicrobial resistance detection methods for bloodstream infection in solid organ transplantation: Proposed clinical guidance, unmet needs, and future directions
Turbett S, Banach D, Bard J, Gandhi R, Letourneau A, Azar M. Rapid antimicrobial resistance detection methods for bloodstream infection in solid organ transplantation: Proposed clinical guidance, unmet needs, and future directions. Transplant Infectious Disease 2023, 25: e14113. PMID: 37594214, DOI: 10.1111/tid.14113.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsUnmet needSolid organ transplant recipientsOrgan transplant recipientsSolid organ transplantationTransplant infectious diseasesEffective antimicrobial therapyPositive blood culturesFast institutionSOT recipientsTransplant recipientsDiagnostic stewardshipBloodstream infectionsAntimicrobial therapyBlood culturesClinical guidanceOrgan transplantationConsensus conferenceClinical practiceInfectious diseasesClinical microbiologyAmerican SocietyTransplantationResistance detectionBacterial resistanceRecipients
2022
A consensus conference to define the utility of advanced infectious disease diagnostics in solid organ transplant recipients
Azar MM, Turbett S, Gaston D, Gitman M, Razonable R, Koo S, Hanson K, Kotton C, Silveira F, Banach DB, Basu SS, Bhaskaran A, Danziger-Isakov L, Bard JD, Gandhi R, Hanisch B, John TM, John A, Letourneau AR, Luong M, Maron G, Miller S, Prinzi A, Schwartz I, Simner P, Kumar D, Group O. A consensus conference to define the utility of advanced infectious disease diagnostics in solid organ transplant recipients. American Journal Of Transplantation 2022, 22: 3150-3169. PMID: 35822346, DOI: 10.1111/ajt.17147.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOrgan transplant recipientsTransplant recipientsConsensus conferenceSolid organ transplant recipientsInfectious diseasesSetting of transplantationInfectious disease diagnosticsTransplant infectious diseasesHigh-quality evidenceEvidence-based recommendationsMultiplex molecular assaysNext-generation sequencing assayDiagnostic stewardshipConsensus statementUnmet needMass spectrometry-based assayClinical useRecipientsClinical microbiologyMolecular assaysAmerican SocietyTransplantationFinancial barriersDiseaseSequencing assays
2020
Emerging Microbiology Diagnostics for Transplant Infections: On the Cusp of a Paradigm Shift.
Azar MM, Gaston DC, Kotton CN, Malinis MF. Emerging Microbiology Diagnostics for Transplant Infections: On the Cusp of a Paradigm Shift. Transplantation 2020, 104: 1358-1384. PMID: 31972701, DOI: 10.1097/tp.0000000000003123.BooksConceptsHematopoietic stem cell transplantationInfected transplant recipientsInfectious disease specialistsStem cell transplantationBlood culture specimensArray of pathogensTransplant recipientsTransplant cliniciansClinical outcomesDisease specialistsCell transplantationTransplant infectionsMagnetic resonance-based methodsMicrobiology diagnosticsSolid organsCulture specimensMolecular testingMolecular panelResistance determinantsInfectionOutcomesDiagnostic microbiologyResonance-based methodsPatientsTransplantation
2019
Allogeneic stem cell transplantation and combination antiretroviral therapy: cautions, complications, and considerations
Shallis RM, Gleeson S, Azar M, Malinis M, Xu ML, Seropian SE, Gowda L, Zeidan AM. Allogeneic stem cell transplantation and combination antiretroviral therapy: cautions, complications, and considerations. Leukemia & Lymphoma 2019, 60: 2584-2587. PMID: 30943051, DOI: 10.1080/10428194.2019.1594221.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2018
Case 1-2018: A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure
Hibbert KA, Shepard JO, Lane RJ, Azar MM. Case 1-2018: A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure. New England Journal Of Medicine 2018, 378: 182-190. PMID: 29320657, DOI: 10.1056/nejmcpc1712222.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAdenoviridaeAdenoviridae InfectionsAdultAntiviral AgentsCidofovirCytosineDiagnosis, DifferentialFemaleHumansImmunocompromised HostLeukemia, Myeloid, AcuteLungNasopharynxOpportunistic InfectionsOrganophosphonatesRadiography, ThoracicRenal InsufficiencyRespiratory InsufficiencyStem Cell TransplantationTomography, X-Ray ComputedViral Load
2017
Case 30-2017
Bhattacharyya RP, Flores EJ, Azar MM. Case 30-2017. New England Journal Of Medicine 2017, 377: 1274-1282. PMID: 28953442, DOI: 10.1056/nejmcpc1706100.Peer-Reviewed Case Reports and Technical NotesDonor-Derived Transmission of Candida auris During Lung Transplantation
Azar MM, Turbett SE, Fishman JA, Pierce VM. Donor-Derived Transmission of Candida auris During Lung Transplantation. Clinical Infectious Diseases 2017, 65: 1040-1042. PMID: 28520901, DOI: 10.1093/cid/cix460.Peer-Reviewed Case Reports and Technical NotesConceptsStringent infection control measuresCandida aurisImportant public health implicationsDonor-derived transmissionLung transplant recipientsInfection control measuresPrevention of transmissionPublic health implicationsLung transplantationTransplant recipientsHigh mortalityC. aurisResistant pathogensHealth implicationsTransplantationAurisControl measuresInfectionMortalityRecipientsPrevention
2016
Disseminated Mycobacterium tuberculosis following renal transplant with alemtuzumab induction
Baghban A, Azar MM, Bernardo RM, Malinis M. Disseminated Mycobacterium tuberculosis following renal transplant with alemtuzumab induction. BMJ Case Reports 2016, 2016: bcr2016217998. PMID: 27852682, PMCID: PMC5129162, DOI: 10.1136/bcr-2016-217998.Peer-Reviewed Case Reports and Technical NotesConceptsMycobacterium tuberculosisDisseminated Mycobacterium tuberculosisIsoniazid preventative therapyHigh-risk patientsSolid organ transplantsOngoing risk factorsAlemtuzumab inductionDisseminated tuberculosisInduction immunosuppressionPeritransplant periodRenal transplantRenal transplantationPulmonary tuberculosisTuberculosis infectionPreventative therapyRisk factorsOrgan transplantsTuberculosisPatientsTransplantAvailable literatureImmunosuppressionTransplantationUnique challengesTherapy