2022
Laboratory Diagnosis for SARS-CoV-2 Infection
Christensen BB, Azar MM, Turbett SE. Laboratory Diagnosis for SARS-CoV-2 Infection. Infectious Disease Clinics Of North America 2022, 36: 327-347. PMID: 35636903, PMCID: PMC9141924, DOI: 10.1016/j.idc.2022.02.002.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionClinical syndromeMolecular testingPatient's clinical syndromeReverse transcriptase-polymerase chain reactionOptimal diagnostic testCOVID-19 infectionSymptom onsetAcute infectionAntigen testingSerologic testingAcute diagnosisPolymerase chain reactionLaboratory diagnosisDiagnostic testsInfectionChain reactionDiagnosisSyndromeTesting
2021
Increased Detection of Mycobacterium tuberculosis Disease Using a Tissue-Based Laboratory-Developed Polymerase Chain Reaction Assay Compared to Standard Diagnostics.
Mackow NA, Abi-Raad R, Kerantzas CA, Hui P, Malinis M, Azar MM. Increased Detection of Mycobacterium tuberculosis Disease Using a Tissue-Based Laboratory-Developed Polymerase Chain Reaction Assay Compared to Standard Diagnostics. American Journal Of Tropical Medicine And Hygiene 2021, 105: 1657-1661. PMID: 34544041, PMCID: PMC8641361, DOI: 10.4269/ajtmh.21-0104.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCulture TechniquesFemaleHumansLungLymph NodesMaleMiddle AgedMycobacterium tuberculosisPleuraReal-Time Polymerase Chain ReactionReference StandardsRetrospective StudiesSensitivity and SpecificitySputumTuberculosisTuberculosis, Lymph NodeTuberculosis, Multidrug-ResistantTuberculosis, PleuralTuberculosis, PulmonaryConceptsComposite reference standardMTB PCRAFB cultureMycobacterium tuberculosisPolymerase chain reactionAcid-fast bacilli smearMycobacterium tuberculosis diseasePositive AFB cultureChain reactionReal-time polymerase chain reactionStandard diagnosticsBacilli smearMTB casesTuberculosis diseaseClinical sensitivityLong turnaround timeXpertClinical performanceReference standardPCRVariable sensitivityTurnaround timeLymphPatientsTuberculosis
2020
Diagnostic Testing of COVID-19 in Solid Organ Transplantation: Current Clinical Application and Future Strategies
Trubin PA, Azar MM, Malinis M. Diagnostic Testing of COVID-19 in Solid Organ Transplantation: Current Clinical Application and Future Strategies. Current Transplantation Reports 2020, 7: 390-398. PMID: 33134033, PMCID: PMC7585558, DOI: 10.1007/s40472-020-00307-w.Peer-Reviewed Original ResearchSARS-CoV-2 infectionSolid organ transplantationInfection prevention practicesOrgan transplantationTransplant recipientsPolymerase chain reactionAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSolid organ transplant recipientsSyndrome coronavirus 2 infectionPrevention practicesCOVID-19 pandemicRecipient suitabilityCoronavirus 2 infectionOrgan transplant recipientsChain reactionCoronavirus disease 2019SARS-CoV-2Current clinical applicationsDiagnostic testing strategiesCOVID-19 diagnosticsMitigation of infectionPurpose of ReviewWhileOptimal donorViral kinetics
2019
Use of Routine Complete Blood Count Results to Rule Out Anaplasmosis Without the Need for Specific Diagnostic Testing
Turbett SE, Anahtar MN, Pattanayak V, Azar MM, Coffey KC, Eng G, Rudolf JW, Lewandrowski KB, Baron J, Rosenberg ES, Branda JA. Use of Routine Complete Blood Count Results to Rule Out Anaplasmosis Without the Need for Specific Diagnostic Testing. Clinical Infectious Diseases 2019, 70: 1215-1221. PMID: 31044232, PMCID: PMC7346887, DOI: 10.1093/cid/ciz346.Peer-Reviewed Original ResearchConceptsComplete blood countWhite blood cellsPolymerase chain reactionBlood countLiver function test resultsRoutine complete blood countMedical record reviewSpecific diagnostic testingFunction test resultsRoutine laboratory testsPositive PCR resultsTrue positive casesTrue negative casesLaboratory abnormalitiesRecord reviewRetrospective reviewPlatelet countClinical criteriaTime of testingProspective phasePCR testingPLT countStewardship programsClinical situationsDiagnostic testing
2018
1988. Development of a Laboratory Stewardship Algorithm for Anaplasma phagocytophilum Polymerase Chain Reaction Testing
Anahtar M, Pattanayak V, Branda J, Azar M, Coffey K, Eng G, Rudolf J, Baron J, Lewandrowski K, Turbett S. 1988. Development of a Laboratory Stewardship Algorithm for Anaplasma phagocytophilum Polymerase Chain Reaction Testing. Open Forum Infectious Diseases 2018, 5: s578-s578. PMCID: PMC6253421, DOI: 10.1093/ofid/ofy210.1644.Peer-Reviewed Original ResearchWhite blood cellsPolymerase chain reactionClinical criteriaPCR testMedian white blood cellPolymerase chain reaction testingComplete blood count valuesBlood count valuesLow positivity ratePreferred diagnostic methodAnaplasma infectionMann-Whitney testChart reviewLaboratory abnormalitiesUnstable patientsClinical parametersPositivity ratePCR testingPLT countReaction testingTypical laboratory abnormalitiesPatientsNegative casesRoche Diagnostics
2017
Graft loss among renal-transplant recipients with early reduction of immunosuppression for BK viremia
Azar MM, Assi R, Valika AK, Banach DB, Hall IE, Landry ML, Malinis MF. Graft loss among renal-transplant recipients with early reduction of immunosuppression for BK viremia. World Journal Of Transplantation 2017, 7: 269-275. PMID: 29104861, PMCID: PMC5661124, DOI: 10.5500/wjt.v7.i5.269.Peer-Reviewed Original ResearchRenal transplant recipientsGraft lossBK viremiaImmunosuppression reductionAcute rejectionEarly reductionTransplant recipientsPolymerase chain reactionCopies/Death-censored graft lossDeceased donor kidney transplantationKidney transplant recipientsDonor kidney transplantationRenal transplant biopsiesCopies/mLQuantitative polymerase chain reactionGraft functionKidney transplantationTransplant biopsiesMedian ageMonths 1PyVANBKV DNALower incidenceRetrospective analysis