2021
Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions
Dehner CA, Ruff WE, Greiling T, Pereira MS, Redanz S, McNiff J, Girardi M, Kriegel MA. Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions. JID Innovations 2021, 2: 100084. PMID: 35199089, PMCID: PMC8844718, DOI: 10.1016/j.xjidi.2021.100084.Peer-Reviewed Original ResearchCutaneous T-cell lymphomaT cell activationSkin microbiotaAppropriate genetic backgroundCell activationBacillus speciesCutaneous T-cell lymphoma lesionsUnique microbiotaHuman commensalGenetic backgroundCell explantsClonal T-cell proliferationSkin-homing CD4T-cell lymphomaAdaptive immune responsesCell interactionsT cell proliferationT cell interactionsEnvironmental factorsMicrobial triggersMicrobiotaCommensalCTCL lesionsLymphoma lesionsCytokine secretion
2018
Skin Microbiota as Antigenic Triggers for Cutaneous T Cell Lymphoma
Dehner C, Ruff W, Foss F, Girardi M, Kriegel M. Skin Microbiota as Antigenic Triggers for Cutaneous T Cell Lymphoma. The Journal Of Immunology 2018, 200: 166.24-166.24. DOI: 10.4049/jimmunol.200.supp.166.24.Peer-Reviewed Original ResearchCutaneous T-cell lymphomaT-cell lymphomaT cellsSkin lesionsCell lymphomaPathogenesis of CTCLActive skin lesionsCutaneous T-cellChronic skin lesionsAdaptive immune responsesPatient T cellsSLE patientsCTCL patientsAntigenic triggerLesional skinRRNA sequencingAntigenic challengeMALT lymphomaHealthy donorsImmune responseAntigenic driversSkin commensalsPatient biopsiesClonal proliferationV1-3