2022
Evolving concepts of host–pathobiont interactions in autoimmunity
Pereira M, Kriegel M. Evolving concepts of host–pathobiont interactions in autoimmunity. Current Opinion In Immunology 2022, 80: 102265. PMID: 36444784, DOI: 10.1016/j.coi.2022.102265.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAutoimmune diseasesSecondary lymphoid tissuesUnconventional therapeutic approachesAutoimmune pathwaysMucosal sitesLymphoid tissueMultistep pathogenesisTherapeutic approachesImmune functionMultifactorial diseaseDiseasePathobiontsSecretion of metabolitesNon-gut tissuesHuman microbiomeTissueAutoimmunityAutoantigensPathogenesisEnvironmental factorsSecretion
2021
Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions
Dehner CA, Ruff WE, Greiling T, Pereira MS, Redanz S, McNiff J, Girardi M, Kriegel MA. Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions. JID Innovations 2021, 2: 100084. PMID: 35199089, PMCID: PMC8844718, DOI: 10.1016/j.xjidi.2021.100084.Peer-Reviewed Original ResearchCutaneous T-cell lymphomaT cell activationSkin microbiotaAppropriate genetic backgroundCell activationBacillus speciesCutaneous T-cell lymphoma lesionsUnique microbiotaHuman commensalGenetic backgroundCell explantsClonal T-cell proliferationSkin-homing CD4T-cell lymphomaAdaptive immune responsesCell interactionsT cell proliferationT cell interactionsEnvironmental factorsMicrobial triggersMicrobiotaCommensalCTCL lesionsLymphoma lesionsCytokine secretion