2018
Blue-green discoloration of urine and false nephrotic range proteinuria at dipstick urinalysis
Poloni J, de Moraes Sassi M, de Oliveira T, Rotta L, Perazella M. Blue-green discoloration of urine and false nephrotic range proteinuria at dipstick urinalysis. Clinica Chimica Acta 2018, 482: 74-77. PMID: 29608875, DOI: 10.1016/j.cca.2018.03.036.Peer-Reviewed Original ResearchConceptsHigh-power fieldCells/high power fieldLeukocytes/high-power fieldBlue-green discolorationUrine samplesRenal tubular epithelial cellsNephrotic range proteinuriaUrinary tract infectionYear old womanUrine protein concentrationTubular epithelial cellsAlbumin 3Range proteinuriaTract infectionsCellular castsDipstick urinalysisEmergency departmentUrine sedimentBilirubin 2Epithelial cellsPower fieldUrinalysisMethylthioninium chloride
2010
Experience with outpatient computed tomographic-guided renal biopsy.
Margaryan A, Perazella MA, Mahnensmith RL, Abu-Alfa AK. Experience with outpatient computed tomographic-guided renal biopsy. Clinical Nephrology 2010, 74: 440-5. PMID: 21084047, DOI: 10.5414/cnp74440.Peer-Reviewed Original ResearchConceptsNative kidney biopsiesKidney biopsyRenal biopsyPost-biopsy observation periodInpatient observation periodObservation periodLow complication rateTime of admissionYale-New Haven Medical CenterDuration of procedureInstances of deathHemoglobin concentration changesDetectable bleedingSerum creatinineComplication rateMean ageRenal sizeAdequate tissueMedical CenterOutpatient unitDiagnostic tissueBiopsyLaboratory dataTransfusionPatients
2001
Indinavir nephropathy revisited: A pattern of insidious renal failure with identifiable risk factors
Reilly R, Tray K, Perazella M. Indinavir nephropathy revisited: A pattern of insidious renal failure with identifiable risk factors. American Journal Of Kidney Diseases 2001, 38: e23.1-e23.6. PMID: 11576910, DOI: 10.1053/ajkd.2001.27732.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusRenal failureSerum creatinineRisk factorsDiffuse interstitial infiltratesElevated serum creatinineAcute renal failureIdentifiable risk factorsProgressive tubulointerstitial injuryIndinavir therapyFlank painHepatitis CTubulointerstitial injuryTubulointerstitial lesionsPositive patientsRenal injuryRenal biopsyInterstitial infiltratesImmunodeficiency virusNumerous eosinophilsFocal necrosisRenal syndromeProgressive riseIndinavirPotential mechanisms
1998
Malignant Hypertension
Perazella M, Mahnensmith R. Malignant Hypertension. New England Journal Of Medicine 1998, 339: 1985. PMID: 9869670, DOI: 10.1056/nejm199812313392705.Peer-Reviewed Original ResearchAcute Renal Failure and Intravenous Immune Globulin
Perazella M, Cayco A. Acute Renal Failure and Intravenous Immune Globulin. American Journal Of Therapeutics 1998, 5: 399-404. PMID: 10099084, DOI: 10.1097/00045391-199811000-00008.Peer-Reviewed Original ResearchConceptsAcute renal failureRenal failureRenal insufficiencyIntravenous immune globulin therapyImmune globulin therapyChronic renal insufficiencyIntravenous immune globulinAcute renal insufficiencyRenal replacement therapyVariety of complicationsGlobulin therapyIVIG infusionIVIG therapyMaintenance dialysisRenal impairmentImmune globulinIVIG preparationsReplacement therapyDrug trialsNumber of casesClinical disordersOlder agePrecise causeTherapyAdverse effectsLeg Pain and Swelling in an HIV-Infected Drug Abuser
Formica R, Perazella M. Leg Pain and Swelling in an HIV-Infected Drug Abuser. Hospital Practice 1998, 33: 195-197. PMID: 9793550, DOI: 10.1080/21548331.1998.11443771.Peer-Reviewed Original ResearchReduction in arteriovenous graft impairment: Results of a vascular access surveillance protocol
Cayco A, Abu-Alfa A, Mahnensmith R, Perazella M. Reduction in arteriovenous graft impairment: Results of a vascular access surveillance protocol. American Journal Of Kidney Diseases 1998, 32: 302-308. PMID: 9708617, DOI: 10.1053/ajkd.1998.v32.pm9708617.Peer-Reviewed Original ResearchConceptsDynamic venous pressureHistorical control groupVenous pressureArteriovenous graftsSurveillance protocolStudy groupBlood flow rateThrombosis rateControl groupSimilar historical control groupHemodialysis vascular accessSynthetic arteriovenous graftsLower thrombosis rateML/minGraft impairmentVenous stenosisHD sessionVascular accessVascular stenosisPatientsScreening testStenosisStudy periodFrustrating problemConsecutive readings
1997
Biochemical aberrations in a dialysis patient following parathyroidectomy
Cruz D, Perazella M. Biochemical aberrations in a dialysis patient following parathyroidectomy. American Journal Of Kidney Diseases 1997, 29: 759-768. PMID: 9159312, DOI: 10.1016/s0272-6386(97)90131-1.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseSevere secondary hyperparathyroidismCalcitriol therapySurgical parathyroidectomyIntensive regimenSecondary hyperparathyroidismElectrolyte abnormalitiesRenal osteodystrophySevere hypocalcemiaDialysis patientsRenal diseasePostoperative managementHigh riskParathyroidectomyPatientsBiochemical aberrationsCommon problemHyperparathyroidismHypocalcemiaHyperkalemiaHypophosphatemiaOsteodystrophyRegimenAberrationsTherapyBone marrow transplant nephropathy: a case report and review of the literature.
Cruz D, Perazella M, Mahnensmith R. Bone marrow transplant nephropathy: a case report and review of the literature. Journal Of The American Society Of Nephrology 1997, 8: 166-73. PMID: 9013462, DOI: 10.1681/asn.v81166.Peer-Reviewed Original ResearchConceptsBone marrow transplant nephropathyBone marrow transplantationRenal injuryTransplant nephropathyMarrow transplantationLate renal injuryEarly renal injuryHemolytic uremic syndromeVariety of causesNephrotoxic medicationsRenal failurePathologic featuresCase reportUremic syndromeLate effectsRadiation therapyRenal syndromeSyndromeNephropathySubsequent treatmentTransplantationInjuryMedicationsChemotherapyReview
1996
Hyperkalemia in hospitalized patients treated with trimethoprim-sulfamethoxazole.
Alappan R, Perazella M, Buller G. Hyperkalemia in hospitalized patients treated with trimethoprim-sulfamethoxazole. Annals Of Internal Medicine 1996, 124: 316-20. PMID: 8554227, DOI: 10.7326/0003-4819-124-3-199602010-00006.Peer-Reviewed Original ResearchConceptsSerum potassium concentrationSerum creatinine levelsMumol/LBlood urea nitrogen levelsPeak potassium concentrationTrimethoprim-sulfamethoxazole therapyCreatinine levelsUrea nitrogen levelsTrimethoprim-sulfamethoxazoleTreatment groupsPotassium concentrationControl groupCommunity-based teaching hospitalDevelopment of hyperkalemiaDays of therapyProspective chart reviewConcurrent renal insufficiencyRenal insufficiencyChart reviewSevere hyperkalemiaHospitalized patientsSerum sodiumTeaching hospitalAnion gapPatients
1995
Enalapril treatment of posttransplant erythrocytosis: efficacy independent of circulating erythropoietin levels
Perazella M, McPhedran P, Kliger A, Lorber M, Levy E, Bia M. Enalapril treatment of posttransplant erythrocytosis: efficacy independent of circulating erythropoietin levels. American Journal Of Kidney Diseases 1995, 26: 495-500. PMID: 7645558, DOI: 10.1016/0272-6386(95)90496-4.Peer-Reviewed Original ResearchConceptsRed blood cell massBlood cell massErythropoietin levelsEnalapril therapyPosttransplant erythrocytosisHemoglobin concentrationMU/mLElevated red blood cell massMean reticulocyte countRed blood cell destructionRenal transplant patientsMean pretreatment valuePlasma volume contractionMean levelsMean hemoglobin concentrationBlood cell destructionRed blood cell productionMechanism of actionEnalapril treatmentTransplant patientsMean hematocritPretreatment valuesBlood cell productionReticulocyte countEnzyme inhibitors
1994
Acute Nonspecific Illness in an AIDS Patient with Dysphagia
Perazella M, Sadigh M. Acute Nonspecific Illness in an AIDS Patient with Dysphagia. Hospital Practice 1994, 29: 39-47. PMID: 7962235, DOI: 10.1080/21548331.1994.11443104.Peer-Reviewed Original Research
1993
NSAID Nephrotoxicity Revisited: Acute Renal Failure Due to Parenteral Ketorolac
PERAZELLA M, BULLER G. NSAID Nephrotoxicity Revisited: Acute Renal Failure Due to Parenteral Ketorolac. Southern Medical Journal 1993, 86: 1421-1424. PMID: 8272928, DOI: 10.1097/00007611-199312000-00025.Peer-Reviewed Original ResearchConceptsNSAID nephrotoxicityAcute renal failureSevere postoperative painMajor surgical proceduresKetorolac therapyParenteral ketorolacRenal hypoperfusionNonsurgical patientsPostoperative painRenal insufficiencyElderly patientsNonnarcotic analgesicsOral NSAIDsRenal failureRenal functionSuch patientsUrine outputSurgical proceduresKetorolacPatientsMedical literatureNephrotoxicitySuch proceduresSame degreeHypoperfusionSuccessful Treatment of Cystinuria With Captopril
Perazella M, Buller G. Successful Treatment of Cystinuria With Captopril. American Journal Of Kidney Diseases 1993, 21: 504-507. PMID: 8488818, DOI: 10.1016/s0272-6386(12)80396-9.Peer-Reviewed Original ResearchConceptsIntolerable side effectsAdverse drug effectsAutosomal recessive hereditary disorderUrinary cystine excretionRecessive hereditary disorderOral alkaliRecurrent nephrolithiasisCystine excretionAttendant complicationsSuccessful treatmentCystine solubilityDrug managementTraditional therapiesDrug effectsSide effectsCystinuric patientsD-penicillamineHereditary disorderCaptoprilPatientsCystinuriaNephrolithiasisMarked declineTraditional managementComplications