1997
Hyperkalemia in the Elderly
Perazella M, Mahnensmith R. Hyperkalemia in the Elderly. Journal Of General Internal Medicine 1997, 12: 646-656. PMID: 9346463, PMCID: PMC1497179, DOI: 10.1046/j.1525-1497.1997.07128.x.Peer-Reviewed Original ResearchConceptsDevelopment of hyperkalemiaPotassium-altering medicationsAppropriate managementPrevention of hyperkalemiaHigh-risk medicationsManagement of hyperkalemiaCellular potassium uptakePlasma potassium concentrationPertinent review articlesCardiac complicationsElderly patientsPotassium handlingRenal functionSevere hyperkalemiaCertain medicationsElectrolyte disordersGeriatric patientsClinical manifestationsElderly subjectsMEDLINE searchHyperkalemiaMedicationsDisease processRenal disposalPotassium levels
1996
Trimethoprim-sulfamethoxazole: hyperkalemia is an important complication regardless of dose.
Perazella M, Mahnensmith R. Trimethoprim-sulfamethoxazole: hyperkalemia is an important complication regardless of dose. Clinical Nephrology 1996, 46: 187-92. PMID: 8879854.Peer-Reviewed Original ResearchConceptsTrimethoprim-sulfamethoxazole therapyStandard doseDevelopment of hyperkalemiaTrimethoprim-sulfamethoxazole useMild renal insufficiencyProspective surveillance studyPotassium-sparing diuretic amilorideRenal potassium excretionPneumocystis carinii pneumoniaLethal adverse reactionHandful of casesRenal insufficiencyElderly patientsPotassium excretionSevere hyperkalemiaImportant complicationAIDS patientsCarinii pneumoniaTrimethoprim-sulfamethoxazoleAdverse reactionsInduced hyperkalemiaPotassium disordersHyperkalemiaSurveillance studyPatients
1993
NSAID Nephrotoxicity Revisited: Acute Renal Failure Due to Parenteral Ketorolac
PERAZELLA M, BULLER G. NSAID Nephrotoxicity Revisited: Acute Renal Failure Due to Parenteral Ketorolac. Southern Medical Journal 1993, 86: 1421-1424. PMID: 8272928, DOI: 10.1097/00007611-199312000-00025.Peer-Reviewed Original ResearchConceptsNSAID nephrotoxicityAcute renal failureSevere postoperative painMajor surgical proceduresKetorolac therapyParenteral ketorolacRenal hypoperfusionNonsurgical patientsPostoperative painRenal insufficiencyElderly patientsNonnarcotic analgesicsOral NSAIDsRenal failureRenal functionSuch patientsUrine outputSurgical proceduresKetorolacPatientsMedical literatureNephrotoxicitySuch proceduresSame degreeHypoperfusion