2009
ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor
Alvarado D, Klein DE, Lemmon MA. ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor. Nature 2009, 461: 287-291. PMID: 19718021, PMCID: PMC2762480, DOI: 10.1038/nature08297.Peer-Reviewed Original Research
2008
Harnessing Novel Secreted Inhibitors of EGF Receptor Signaling for Breast Cancer Treatment
Lemmon M. Harnessing Novel Secreted Inhibitors of EGF Receptor Signaling for Breast Cancer Treatment. 2008 DOI: 10.21236/ada488172.Peer-Reviewed Original ResearchEGF receptor family membersEGF receptor signalingEGF-like ligandsReceptor family membersNew structural informationFruit flyYeast surface displayEGF receptorEGFR ligandsSecreted inhibitorsProtein scaffoldsReceptor signalingFunctional fragmentsSurface displayHuman EGFProtein therapeuticsTherapeutic designGrowth factorStructural informationNew therapeuticsExperimental approachStructure determinationFamily membersDrosophilaReceptors
2007
Harnessing Novel Secreted Inhibitors of EGF Receptor Signaling for Breast Cancer Treatment
Lemmon M. Harnessing Novel Secreted Inhibitors of EGF Receptor Signaling for Breast Cancer Treatment. 2007 DOI: 10.21236/ada471085.Peer-Reviewed Original ResearchEGF receptor family membersEGF receptor signalingEGF-like ligandsReceptor family membersNew structural informationFruit flyYeast surface displayEGF receptorSecreted inhibitorsEGFR ligandsProtein scaffoldsReceptor signalingFunctional fragmentsSurface displayHuman EGFProtein therapeuticsTherapeutic designGrowth factorNew therapeuticsStructural informationExperimental approachStructure determinationFamily membersDrosophilaReceptors