2021
The Tumor Microenvironment in Cholangiocarcinoma Progression
Fabris L, Sato K, Alpini G, Strazzabosco M. The Tumor Microenvironment in Cholangiocarcinoma Progression. Hepatology 2021, 73: 75-85. PMID: 32500550, PMCID: PMC7714713, DOI: 10.1002/hep.31410.Peer-Reviewed Original Research
2019
Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances
Sirica AE, Gores GJ, Groopman JD, Selaru FM, Strazzabosco M, Wang X, Zhu AX. Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances. Hepatology 2019, 69: 1803-1815. PMID: 30251463, PMCID: PMC6433548, DOI: 10.1002/hep.30289.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBile Duct NeoplasmsBiomarkersCholangiocarcinomaExtracellular VesiclesHumansImmunotherapyMolecular Targeted TherapyTranslational Research, BiomedicalConceptsIntrahepatic cholangiocarcinomaMortality rateFuture translational research opportunitiesNonalcoholic fatty liver diseasePlatelet-derived growth factor DPrimary hepatobiliary cancerFatty liver diseaseRecent clinical trialsTranslational research findingsHigh mortality rateCancer-associated myofibroblastsTranslational research opportunitiesGrowth factor DNonspecific cirrhosisLiver diseaseHepatobiliary cancersSerum biomarkersRisk factorsClinical trialsExtracellular vesicle biomarkersLiver cancerMedical conditionsAggressive cancerIntrahepatic cholangiocarcinogenesisTherapeutic implications