2017
Direct‐acting antivirals combination for elderly patients with chronic hepatitis C: A cost‐effectiveness analysis
Ciaccio A, Cortesi PA, Bellelli G, Rota M, Conti S, Okolicsanyi S, Rota M, Cesana G, Mantovani LG, Annoni G, Strazzabosco M. Direct‐acting antivirals combination for elderly patients with chronic hepatitis C: A cost‐effectiveness analysis. Liver International 2017, 37: 982-994. PMID: 27943549, DOI: 10.1111/liv.13339.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAntiviral AgentsComputer SimulationCost-Benefit AnalysisDecision Support TechniquesDisease ProgressionDrug CostsDrug Therapy, CombinationFemaleFrail ElderlyGeriatric AssessmentHepatitis C, ChronicHumansLiver CirrhosisMaleMarkov ChainsModels, EconomicQuality-Adjusted Life YearsRisk FactorsTime FactorsTreatment OutcomeConceptsIncremental cost-effectiveness ratioChronic hepatitis CQuality-adjusted life yearsCost-effectiveness ratioElderly patientsCHC patientsHepatitis CFrailty phenotypeFrailty statusFibrosis stageLife yearsElderly CHC patientsMild fibrosis stageInterferon-free treatmentHealthcare system perspectiveLifetime time horizonCost-effectiveness analysisDAA treatmentDAA combinationsAdvanced fibrosisFrail subjectsClinical variablesLiver fibrosisF2 patientsAge 75
2016
Effective but costly: How to tackle difficult trade‐offs in evaluating health improving technologies in liver diseases
Mantovani LG, Cortesi PA, Strazzabosco M. Effective but costly: How to tackle difficult trade‐offs in evaluating health improving technologies in liver diseases. Hepatology 2016, 64: 1331-1342. PMID: 26926906, DOI: 10.1002/hep.28527.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical TechnologyCost-Benefit AnalysisDecision Support TechniquesHealth Care CostsHumansLiver DiseasesModels, EconomicConceptsHealth economic evaluationsEconomic evaluationAlternative health care interventionsDecision analytical modelingCost-effectiveness analysisHealth economic analysisDecision analytical modelDecision analytic modelHealth care interventionsEconomic analysisEconomic sustainabilityHealth care costsBudget impactDecision makersMedical innovationCare costsSocioeconomic contextSustainabilityCare interventionsFair accessMarketMakersAnalytical toolsInnovationCurrent context