2004
Cytoplasmic localization of calcium/calmodulin‐dependent protein kinase I‐α depends on a nuclear export signal in its regulatory domain
Stedman DR, Uboha NV, Stedman TT, Nairn AC, Picciotto MR. Cytoplasmic localization of calcium/calmodulin‐dependent protein kinase I‐α depends on a nuclear export signal in its regulatory domain. FEBS Letters 2004, 566: 275-280. PMID: 15147908, DOI: 10.1016/j.febslet.2004.04.042.Peer-Reviewed Original ResearchMeSH KeywordsActive Transport, Cell NucleusAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 1Calcium-Calmodulin-Dependent Protein KinasesConsensus SequenceCytoplasmEnzyme ActivationKaryopherinsMicroscopy, FluorescenceNuclear Localization SignalsPC12 CellsProtein Structure, TertiaryRatsReceptors, Cytoplasmic and NuclearRecombinant Fusion ProteinsSubcellular FractionsTransfectionConceptsNuclear export signalExport signalRegulatory domainCytoplasmic localizationCalmodulin-dependent protein kinase ICalcium/calmodulin-dependent protein kinase IRev-like nuclear export signalProtein kinase IUbiquitous cytosolic enzymeCalcium/calmodulinTranscriptional regulationNuclear exportKinase INuclear proteinsNuclear entryCatalytic coreCytosolic enzymeI alphaSequenceCRM1VitroMutantsLocalizationCalmodulinDomain
2001
Galanin receptor 1 gene expression is regulated by cyclic AMP through a CREB‐dependent mechanism
Zachariou V, Georgescu D, Kansal L, Merriam P, Picciotto M. Galanin receptor 1 gene expression is regulated by cyclic AMP through a CREB‐dependent mechanism. Journal Of Neurochemistry 2001, 76: 191-200. PMID: 11145992, DOI: 10.1046/j.1471-4159.2001.00018.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceCell LineCloning, MolecularCodon, InitiatorColforsinCyclic AMPCyclic AMP Response Element-Binding ProteinGene Expression RegulationMiceMolecular Sequence DataMutagenesis, Site-DirectedNerve Growth FactorNeuronsPromoter Regions, GeneticReceptors, GalaninReceptors, NeuropeptideRegulatory Sequences, Nucleic AcidSequence Homology, Nucleic AcidTetradecanoylphorbol AcetateTransfectionConceptsLocus coeruleusOpiate withdrawalGalanin binding sitesPeripheral nervous systemCREB-dependent mechanismG protein-coupled receptorsLevels of cAMPProtein-coupled receptorsOpiate analgesiaNeuropeptide galaninGalanin receptorsGalR1 mRNANervous systemPlace preferenceTranscription factor CREBForskolin effectGALR1 expressionGalR1 geneCAMP levelsCyclic AMPCell linesBasal activityCRE-like siteTransient transfection assaysReceptors