2004
Cytoplasmic localization of calcium/calmodulin‐dependent protein kinase I‐α depends on a nuclear export signal in its regulatory domain
Stedman DR, Uboha NV, Stedman TT, Nairn AC, Picciotto MR. Cytoplasmic localization of calcium/calmodulin‐dependent protein kinase I‐α depends on a nuclear export signal in its regulatory domain. FEBS Letters 2004, 566: 275-280. PMID: 15147908, DOI: 10.1016/j.febslet.2004.04.042.Peer-Reviewed Original ResearchMeSH KeywordsActive Transport, Cell NucleusAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 1Calcium-Calmodulin-Dependent Protein KinasesConsensus SequenceCytoplasmEnzyme ActivationKaryopherinsMicroscopy, FluorescenceNuclear Localization SignalsPC12 CellsProtein Structure, TertiaryRatsReceptors, Cytoplasmic and NuclearRecombinant Fusion ProteinsSubcellular FractionsTransfectionConceptsNuclear export signalExport signalRegulatory domainCytoplasmic localizationCalmodulin-dependent protein kinase ICalcium/calmodulin-dependent protein kinase IRev-like nuclear export signalProtein kinase IUbiquitous cytosolic enzymeCalcium/calmodulinTranscriptional regulationNuclear exportKinase INuclear proteinsNuclear entryCatalytic coreCytosolic enzymeI alphaSequenceCRM1VitroMutantsLocalizationCalmodulinDomain
1996
Structure, Regulation, and Function of Calcium/Calmodulin-Dependent Protein Kinase I
Picciotto M, Nastiuk K, Nairn A. Structure, Regulation, and Function of Calcium/Calmodulin-Dependent Protein Kinase I. Advances In Pharmacology 1996, 36: 251-275. PMID: 8783563, DOI: 10.1016/s1054-3589(08)60585-2.Peer-Reviewed Original ResearchConceptsProtein kinaseProtein kinase CMyosin light chain kinaseKinase ICaM kinaseSecond messenger-regulated protein kinasesCalmodulin-dependent protein kinase ICalcium/calmodulin-dependent protein kinase ICAMP-dependent protein kinaseSpecific subcellular locationsMultifunctional protein kinaseTerminal regulatory domainDependent protein kinaseCaM kinase familyClass of enzymesProtein kinase ICaM kinase IAmino acid residuesMyosin P-light chainDomain bindsAutoinhibitory mechanismRegulatory domainKinase familyProtein phosphorylationLight chain kinase