2017
Access to nicotine in drinking water reduces weight gain without changing caloric intake on high fat diet in male C57BL/6J mice
Calarco CA, Lee S, Picciotto MR. Access to nicotine in drinking water reduces weight gain without changing caloric intake on high fat diet in male C57BL/6J mice. Neuropharmacology 2017, 123: 210-220. PMID: 28623168, PMCID: PMC5544033, DOI: 10.1016/j.neuropharm.2017.06.012.Peer-Reviewed Original ResearchConceptsHigh-fat dietCaloric intakeWeight gainFat dietFemale miceMale miceBody weightAdipose tissueEffects of HFDOverall caloric intakeAmphetamine-regulated transcriptNicotinic acetylcholine receptor subunitsLower body weightMelanin-concentrating hormoneSex-dependent mannerRegulation of agoutiChow-fed animalsAcetylcholine receptor subunitsNicotine administrationChronic consumptionArcuate nucleusNicotine dosesNicotine intakeFood intakeTobacco use
2006
Nicotine withdrawal increases body weight, neuropeptide Y and Agouti-related protein expression in the hypothalamus and decreases uncoupling protein-3 expression in the brown adipose tissue in high-fat fed mice
Fornari A, Pedrazzi P, Lippi G, Picciotto MR, Zoli M, Zini I. Nicotine withdrawal increases body weight, neuropeptide Y and Agouti-related protein expression in the hypothalamus and decreases uncoupling protein-3 expression in the brown adipose tissue in high-fat fed mice. Neuroscience Letters 2006, 411: 72-76. PMID: 17052838, DOI: 10.1016/j.neulet.2006.10.014.Peer-Reviewed Original ResearchMeSH KeywordsAdipose Tissue, BrownAgouti Signaling ProteinAgouti-Related ProteinAnalysis of VarianceAnimalsBody WeightDietary FatsHypothalamusIntercellular Signaling Peptides and ProteinsIon ChannelsMaleMiceMice, Inbred C57BLMitochondrial ProteinsNeuropeptide YNicotineNicotinic AgonistsReceptors, Adrenergic, betaSubstance Withdrawal SyndromeUncoupling Protein 3ConceptsNicotine withdrawalBrown adipose tissueBody weightNeuropeptide YAdipose tissueOrexigenic peptides neuropeptide YHigh-fat fed miceChronic nicotine treatmentPeptides neuropeptide YHigh-fat dietAbility of nicotineBody weight regulationProtein 3 expressionAnorectic effectNicotine treatmentSmoking cessationFat dietFed miceHuman smokersNormal rodentsWeight regulationIncreased expressionProtein 3Protein expressionExposure results