2024
Coexistent Eosinophilic Esophagitis and Dysplastic Barrett's Esophagus With Rapid Eosinophilic Infiltration of Neosquamous Mucosa After Radiofrequency Ablation
Ameyaw P, Parsons D, Mahmoud A, Marie R, Nagar A, Aslanian H. Coexistent Eosinophilic Esophagitis and Dysplastic Barrett's Esophagus With Rapid Eosinophilic Infiltration of Neosquamous Mucosa After Radiofrequency Ablation. ACG Case Reports Journal 2024, 11: e01488. PMID: 39221230, PMCID: PMC11361630, DOI: 10.14309/crj.0000000000001488.Peer-Reviewed Original ResearchBarrett's esophagusRadiofrequency ablationDysplastic BEEosinophilic esophagitisOutcomes of radiofrequency ablationNeosquamous mucosaAssociation of gastroesophageal reflux diseaseEndoscopic eradication therapyDysplastic Barrett's esophagusGastroesophageal reflux diseaseEradication therapyEosinophil infiltrationReflux diseasePatientsEsophagealEoEEsophagusMucosaAblationRadiofrequency
2023
Guidelines for best practices in monitoring established coeliac disease in adult patients
Elli L, Leffler D, Cellier C, Lebwohl B, Ciacci C, Schumann M, Lundin K, Chetcuti Zammit S, Sidhu R, Roncoroni L, Bai J, Lee A, Dennis M, Robert M, Rostami K, Khater S, Comino I, Cebolla A, Branchi F, Verdu E, Stefanolo J, Wolf R, Bergman-Golden S, Trott N, Scudeller L, Zingone F, Scaramella L, Sanders D. Guidelines for best practices in monitoring established coeliac disease in adult patients. Nature Reviews Gastroenterology & Hepatology 2023, 21: 198-215. PMID: 38110546, DOI: 10.1038/s41575-023-00872-2.Peer-Reviewed Original ResearchConceptsCoeliac diseaseLevel of evidenceLife-long gluten-free dietGluten-free dietMucosal atrophyAdult patientsCirculating autoantibodiesFollow-upGenetic predispositionImmunological diseasesRecommendations AssessmentMonitoring patientsClinical guidelinesEvidence levelPatientsConsumption of glutenDiagnosisDiseaseGuidelinesScientific societiesCeDAutoantibodiesGastroenterologistsAtrophyClinical Data Do Not Reliably Predict Duodenal Histology at Follow-up in Celiac Disease
Patel N, Leffler D, Al-Toma A, Mulder C, Elli L, Gan G, Patil P, Atsawarungruangkit A, Kuijpers K, Del Gobbo A, Goldsmith J, Hintze Z, Pacheco M, Vieth M, Melcher B, Salomao M, Pai R, Hart J, Olivas A, Naini B, Meyerson C, Choi W, Kakar S, Westerhoff M, Cheng J, Gopal P, Hammer S, Prats M, Bronner M, Robert M. Clinical Data Do Not Reliably Predict Duodenal Histology at Follow-up in Celiac Disease. The American Journal Of Surgical Pathology 2023, 48: 212-220. PMID: 37994653, DOI: 10.1097/pas.0000000000002150.Peer-Reviewed Original ResearchIntraepithelial lymphocytesCeliac diseaseClinical dataMarsh scoreMucosal recoveryVillous bluntingDuodenal biopsiesMucosal injuryDiet adherenceGluten-free diet adherenceComplete histologic remissionPersistent mucosal injuryMinority of patientsCeliac disease patientsDuodenal histologyHistologic remissionPathologists' awarenessMucosal statusMucosal healingGastrointestinal pathologistsDisease patientsFollow-upPatient managementEligibility criteriaPatients
2022
Open-Capsule Budesonide for the Treatment of Isolated Immune Checkpoint Inhibitor-Induced Enteritis
Hussain N, Robert M, Al-Bawardy B. Open-Capsule Budesonide for the Treatment of Isolated Immune Checkpoint Inhibitor-Induced Enteritis. ACG Case Reports Journal 2022, 9: e00882. PMID: 36237281, PMCID: PMC9553371, DOI: 10.14309/crj.0000000000000882.Peer-Reviewed Original Research
2020
Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis
Takeuchi M, Vidigal PT, Guerra MT, Hundt MA, Robert ME, Olave-Martinez M, Aoki S, Khamphaya T, Kersten R, Kruglov E, de la Rosa Rodriguez R, Banales JM, Nathanson MH, Weerachayaphorn J. Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis. Gut 2020, 70: 342-356. PMID: 33214166, PMCID: PMC7906004, DOI: 10.1136/gutjnl-2020-322540.Peer-Reviewed Original ResearchConceptsBile ductCholestatic changesLimited treatment optionsPresence of cholestasisAbility of neutrophilsLife-threatening diseaseNew therapeutic targetsHuman bile ductIntracellular calcium channelsAlcoholic hepatitisLiver biopsyControl neutrophilsPathological findingsHepatocellular damageHistological findingsTreatment optionsCell adhesion moleculeHistological parametersDisease altersITPR3 expressionTherapeutic targetAnimal modelsCalcium channelsNeutrophilsPatients
2019
Mo1984 – Symptom Profiles, Gluten Free Diet Adherence, and Laboratory Data Do Not Reliably Predict Duodenal Mucosal Healing in Follow Up Biopsies from Patients with Celiac Disease in a Multinational Pathology Based Cohort
Patel N, Atsawarungruangkit A, Leffler D, Hart J, Olivas A, Vieth M, Melcher B, Al-toma A, Mulder C, Salomao M, Pai R, Bronner M, Prats M, Naini B, Meyerson C, Elli L, del Gobbo A, Kakar S, Choi W, Gopal P, Westerhoff M, Cheng J, Robert M. Mo1984 – Symptom Profiles, Gluten Free Diet Adherence, and Laboratory Data Do Not Reliably Predict Duodenal Mucosal Healing in Follow Up Biopsies from Patients with Celiac Disease in a Multinational Pathology Based Cohort. Gastroenterology 2019, 156: s-911. DOI: 10.1016/s0016-5085(19)39247-9.Peer-Reviewed Original Research
2018
Statement on Best Practices in the Use of Pathology as a Diagnostic Tool for Celiac Disease
Robert ME, Crowe SE, Burgart L, Yantiss RK, Lebwohl B, Greenson JK, Guandalini S, Murray JA. Statement on Best Practices in the Use of Pathology as a Diagnostic Tool for Celiac Disease. The American Journal Of Surgical Pathology 2018, 42: e44-e58. PMID: 29923907, DOI: 10.1097/pas.0000000000001107.Peer-Reviewed Original ResearchConceptsDuodenal mucosal biopsiesCeliac diseaseMucosal biopsiesPossible celiac diseaseUse of pathologySpecific serological testsUse of endoscopyEndoscopic findingsIntraepithelial lymphocytesPathologic assessmentPathologic findingsVillous architectureNorth American AssociationPathology formsBiopsy interpretationBiopsySerological testsTissue samplingDiseasePatientsDiagnostic toolDiagnosisAmerican AssociationPathologistsCritical appraisal
2010
ChemInform Abstract: Spectrum of Histologic Changes in Colonic Biopsies in Patients Treated with Mycophenolate Mofetil
Selbst M, Ahrens W, Robert M, Friedman A, Proctor D, Jain D. ChemInform Abstract: Spectrum of Histologic Changes in Colonic Biopsies in Patients Treated with Mycophenolate Mofetil. ChemInform 2010, 41: no-no. DOI: 10.1002/chin.201010274.Peer-Reviewed Original Research
2008
A Comparison of Hepatopathologists' and Community Pathologists' Review of Liver Biopsy Specimens From Patients With Hepatitis C
Robert M, Sofair AN, Thomas A, Bell B, Bialek S, Corless C, Van Ness G, Huie–White S, Stabach N, Zaman A. A Comparison of Hepatopathologists' and Community Pathologists' Review of Liver Biopsy Specimens From Patients With Hepatitis C. Clinical Gastroenterology And Hepatology 2008, 7: 335-338. PMID: 19138761, PMCID: PMC4603363, DOI: 10.1016/j.cgh.2008.11.029.Peer-Reviewed Original ResearchConceptsHepatitis C patientsCommunity pathologistsBiopsy specimensC patientsLiver biopsyFibrosis stageInterobserver agreementChronic liver diseaseLiver biopsy specimensPopulation-based studyStage of fibrosisPopulation-based sampleGood overall interobserver agreementOverall interobserver agreementBiopsy specimen sizeDisease surveillance networksHepatitis CLiver histologyLiver diseaseHepatic fibrosisGeneral pathologistsStudy pathologistsHepatopathologistBiopsy samplesPatients
2000
Intraoperative Enteroscopy for Diagnosis of a Bleeding Jejunal Lymphangioma
Ugwonali O, Coady M, Saxena R, Robert M, Horowitz N, Topazian M. Intraoperative Enteroscopy for Diagnosis of a Bleeding Jejunal Lymphangioma. Journal Of Clinical Gastroenterology 2000, 31: 333-335. PMID: 11129277, DOI: 10.1097/00004836-200012000-00013.Peer-Reviewed Original ResearchConceptsIntraoperative enteroscopyJejunal lymphangiomaGastrointestinal bleedingRecurrent gastrointestinal bleedingUnexplained gastrointestinal bleedingPreoperative diagnostic studiesUseful diagnostic techniqueBleeding sourceSmall bowelSonde enteroscopyEnteroscopyLymphangiomaDiagnostic studiesBleedingPatientsDiagnostic techniquesBowelDiagnosis
1996
Carcinoid tumor of the common bile duct producing gastrin and serotonin.
Hao L, Friedman A, Navarro V, West B, Robert M. Carcinoid tumor of the common bile duct producing gastrin and serotonin. Journal Of Clinical Gastroenterology 1996, 23: 63-5. PMID: 8835905, DOI: 10.1097/00004836-199607000-00018.Peer-Reviewed Original Research
1994
Pathology of the lymph nodes in patients with malignant melanoma.
Cochran A, Robert M, Wen D. Pathology of the lymph nodes in patients with malignant melanoma. Pathology 1994, 2: 385-400. PMID: 9420909.Peer-Reviewed Original ResearchConceptsMalignant melanomaLymph nodesLymph node metastases of malignant melanomaMetastases of malignant melanomaRegional lymph node metastasisLymph node dissectionPathological risk factorsPoor survival rateDifficulty of diagnosisVisceral metastasesSelective lymphadenectomyNode dissectionSurvival rateRisk factorsClinical considerationsLymphMelanomaPatientsLymphadenectomyMetastasisPrognosisDissection
1993
Rectal substance P concentrations are increased in ulcerative colitis but not in Crohn's disease.
Bernstein C, Robert M, Eysselein V. Rectal substance P concentrations are increased in ulcerative colitis but not in Crohn's disease. The American Journal Of Gastroenterology 1993, 88: 908-13. PMID: 7684884.Peer-Reviewed Original ResearchConceptsSubstance P concentrationsSubstance P levelsCrohn's diseaseUlcerative colitisSubstance PIncreasing concentrations of substance PConcentrations of substance PPathogenesis of ulcerative colitisRectal mucosal biopsiesNon-inflammatory bowel disease patientsMucosal neutrophilsUC patientsMucosal levelMucosal biopsiesCD patientsAffected patientsIncreased inflammationInflammatory cellsRectal diseaseColonic mucosaInflammatory processPatientsDisease patientsBiopsyMotor phenomena
1992
Familial pulmonary nodular lymphoid hyperplasia
Franchi L, Chin T, Nussbaum E, Riker J, Robert M, Talbert W. Familial pulmonary nodular lymphoid hyperplasia. The Journal Of Pediatrics 1992, 121: 89-92. PMID: 1625100, DOI: 10.1016/s0022-3476(05)82550-8.Peer-Reviewed Original ResearchConceptsSystemic autoimmune disorderHyperplastic lymphoid folliclesElevated immunoglobulin levelsPulmonary compromiseAntinuclear antibodiesAutoimmune disordersChronic hypoxiaDigital clubbingPathological findingsLymphoid folliclesImmunoglobulin levelsSmall airwaysAirwayPatientsEpitheliumFolliclesHypoxiaAntibodiesCerebral Hemorrhage With Biopsy-Proved Amyloid Angiopathy
Yong W, Robert M, Secor D, Kleikamp T, Vinters H. Cerebral Hemorrhage With Biopsy-Proved Amyloid Angiopathy. JAMA Neurology 1992, 49: 51-58. PMID: 1728264, DOI: 10.1001/archneur.1992.00530250055016.Peer-Reviewed Original ResearchConceptsBiopsy specimensAcute clinical presentationComputed tomographic scanFocal neurological deficitsBrain biopsy specimensTransient ischemic attackBiopsy-provedClinical presentationRing enhancementLoss of consciousnessRadiological featuresImpending hemorrhageTomographic scanIntracerebral hemorrhageLobar hemorrhageNeurological deficitsBiopsy materialImmunohistochemical findingsImmunohistochemical studiesIntraparenchymal bleedingHemorrhageCerebral hemorrhageIschemic attackBrain hemorrhagePatients
1989
Severe neuropathy in a patient with acquired immune deficiency syndrome (AIDS)
Robert M, Geraghty J, Miles S, Cornford M, Vinters H. Severe neuropathy in a patient with acquired immune deficiency syndrome (AIDS). Acta Neuropathologica 1989, 79: 255-261. PMID: 2558484, DOI: 10.1007/bf00294659.Peer-Reviewed Original ResearchConceptsAcquired immune deficiency syndromeImmune deficiency syndromeAnterior horn cellsDeficiency syndromeHorn cellsAcquired immune deficiency syndrome patientsSevere peripheral neuropathyNeuromuscular diseasePeripheral nervous systemProgressive neuromuscular disorderCMV infectionHIV infectionSevere neuropathyImmunohistochemical stainingPeripheral neuropathyMuscle wastingSpinal cordPathogenetic mechanismsPatientsPeripheral nervesNervous systemSyndromeNeuromuscular disordersSevere weaknessCell complement