2024
An innovative approach to aligning healthcare with what matters most to patients: A hybrid type 1 trial protocol of patient priorities care for older adults with multiple chronic conditions
Naik A, Shanahan M, Dindo L, Mecca M, Arney J, Amspoker A, Wydermyer S, Banks J, Street R, Kiefer L, Zenoni M, Rosen T, Gonzalez R, Catic A, Fried T. An innovative approach to aligning healthcare with what matters most to patients: A hybrid type 1 trial protocol of patient priorities care for older adults with multiple chronic conditions. Contemporary Clinical Trials 2024, 143: 107613. PMID: 38914308, DOI: 10.1016/j.cct.2024.107613.Peer-Reviewed Original ResearchMultiple chronic conditionsHealth priorityOlder adultsCare approachChronic conditionsTreatment burdenPriorities of older adultsPatient-centered care approachPatient Priorities CarePatients' health prioritiesPrimary care providersVeterans Affairs Medical CenterHealth care decisionsAffairs Medical CenterHigh treatment burdenComplexity of patientsRandomized controlled trialsPrimary careUsual carePriority careCare providersImplementation outcomesCare decisionsCare optionsAssessor-blinded
2022
Effect of Computer-Tailored Print Feedback, Motivational Interviewing, and Motivational Enhancement Therapy on Engagement in Advance Care Planning
Fried T, Yang M, Martino S, Iannone L, Zenoni M, Blakley L, O’Leary J, Redding C, Paiva A. Effect of Computer-Tailored Print Feedback, Motivational Interviewing, and Motivational Enhancement Therapy on Engagement in Advance Care Planning. JAMA Internal Medicine 2022, 182: 1298-1305. PMID: 36342678, PMCID: PMC9641591, DOI: 10.1001/jamainternmed.2022.5074.Peer-Reviewed Original ResearchConceptsAdvance care planningMotivational enhancement therapyMotivational interviewingUsual careClinical trialsCare planningEnhancement therapySingle VA facilityPrimary care visitsPrimary care patientsList of patientsSelf-administered toolClinician-led approachQuantity of lifeACP activityHealth care agentSelf-reported completionOversampling of womenElectronic health recordsCare visitsCare patientsTelephone contactOlder veteransMAIN OUTCOMETelephone assessmentPrimary care clinicians’ use of deprescribing recommendations: A mixed-methods study
Mecca MC, Zenoni M, Fried TR. Primary care clinicians’ use of deprescribing recommendations: A mixed-methods study. Patient Education And Counseling 2022, 105: 2715-2720. PMID: 35523638, DOI: 10.1016/j.pec.2022.04.013.Peer-Reviewed Original ResearchConceptsMedication-related communicationPrimary care cliniciansMedication reconciliationCare cliniciansThorough medication reconciliationClinical decision support toolChronic disease managementAdherence discussionsMedication appropriatenessHypertension medicationsInappropriate medicationsMedication changesIntervention cliniciansHypertension treatmentPrimary careIntervention groupClinician practiceMedicationsIndividualized reportsCliniciansDeintensificationDisease managementMixed-method studyFeedback reportsReport
2021
Effect of the STAMP (Sharing and Talking About My Preferences) Intervention on Completing Multiple Advance Care Planning Activities in Ambulatory Care : A Cluster Randomized Controlled Trial.
Fried TR, Paiva AL, Redding CA, Iannone L, O'Leary JR, Zenoni M, Risi MM, Mejnartowicz S, Rossi JS. Effect of the STAMP (Sharing and Talking About My Preferences) Intervention on Completing Multiple Advance Care Planning Activities in Ambulatory Care : A Cluster Randomized Controlled Trial. Annals Of Internal Medicine 2021, 174: 1519-1527. PMID: 34461035, PMCID: PMC8711627, DOI: 10.7326/m21-1007.Peer-Reviewed Original ResearchConceptsAdvance care planning activitiesCare planning activitiesAmbulatory care settingsAdvance care planningCare planningCare settingsNon-English speaking participantsSpecialty care practicesUsual care sitesPrespecified subgroup analysisPatient sociodemographic informationNational InstituteParticipant-level analysesQuantity of lifeHealth care agentSecondary outcomesUsual carePrimary outcomeControlled TrialsMean ageSubgroup analysisBlinded interviewersAmbulatory careCare sitesPrint interventionCross Disciplinary Role Agreement is Needed When Coordinating Long‐Term Opioid Prescribing for Cancer: a Qualitative Study
Giannitrapani K, Silveira M, Azarfar A, Glassman P, Singer S, Asch S, Midboe A, Zenoni M, Gamboa R, Becker W, Lorenz K. Cross Disciplinary Role Agreement is Needed When Coordinating Long‐Term Opioid Prescribing for Cancer: a Qualitative Study. Journal Of General Internal Medicine 2021, 36: 1867-1874. PMID: 33948790, PMCID: PMC8298631, DOI: 10.1007/s11606-021-06747-z.Peer-Reviewed Original ResearchConceptsPrimary care providersCancer pain managementOpioid pain managementPain managementCancer painCare providersChronic cancer-related painLong-term opioid prescribingCommunity-based outpatient clinicsLarge integrated healthcare systemCancer-related painVA Medical CenterIntegrated healthcare systemResearch team consensusOpioid prescribingOncology providersMultiple prescribersOutpatient clinicPrimary careCare coordinationMedical CenterInterdisciplinary providersPainInterdisciplinary cliniciansProvider experienceHow Patients and Providers Weigh the Risks and Benefits of Long-Term Opioid Therapy for Cancer Pain
Giannitrapani KF, Fereydooni S, Silveira MJ, Azarfar A, Glassman PA, Midboe A, Zenoni M, Becker WC, Lorenz KA. How Patients and Providers Weigh the Risks and Benefits of Long-Term Opioid Therapy for Cancer Pain. JCO Oncology Practice 2021, 17: e1038-e1047. PMID: 33534632, DOI: 10.1200/op.20.00679.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyOpioid therapyCancer painPain managementPatient decision‐making factorsAdequate pain managementOpioid usePatient characteristicsOpioid analgesicsVeteran patientsPatient goalsPrimary carePatient concernsInterdisciplinary providersPatientsPainThematic qualitative methodsProvider experienceTranscribed interview dataPractice settingsSubstance abuseCancer treatmentProvider decisionsOpioidsTherapy
2019
Signature Informed Consent for Long-Term Opioid Therapy in Patients With Cancer: Perspectives of Patients and Providers
Giannitrapani KF, Fereydooni S, Azarfar A, Silveira MJ, Glassman PA, Midboe AM, Bohnert ABS, Zenoni MA, Kerns RD, Pearlman RA, Asch SM, Becker W, Lorenz KA. Signature Informed Consent for Long-Term Opioid Therapy in Patients With Cancer: Perspectives of Patients and Providers. Journal Of Pain And Symptom Management 2019, 59: 49-57. PMID: 31476361, DOI: 10.1016/j.jpainsymman.2019.08.020.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyCancer-related painOpioid therapyVeterans Health Administration medical centersInformed consentAppropriate literacy levelPerspectives of patientsPatient-provider relationshipCancer-related concernsOpioid useOpioid prescribersPatient interviewsPatient educationMedical CenterPatientsPainProvider perspectivesTherapyCancerConsentLiteracy levelsProvidersPotential disadvantagesEmergent themesOpioidsFeasibility of Delivering a Tailored Intervention for Advance Care Planning in Primary Care Practice
Paiva A, Redding CA, Iannone L, Zenoni M, O'Leary JR, Fried TR. Feasibility of Delivering a Tailored Intervention for Advance Care Planning in Primary Care Practice. Journal Of The American Geriatrics Society 2019, 67: 1917-1921. PMID: 31271654, PMCID: PMC6732008, DOI: 10.1111/jgs.16035.Peer-Reviewed Original ResearchConceptsPrimary care practicesCare practicesIntervention participantsAdvance Care Planning EngagementMore intervention participantsControl participantsPrimary care settingBaseline sociodemographic characteristicsAdvance care planningFeedback reportsBaseline characteristicsPractice populationIntervention groupCare settingsPatient recruitmentCare planningIntervention deliveryPilot clusterSociodemographic characteristicsHealthcare agentsStatistical significanceTrialsACP behaviorsIndividualized feedback reportsEmployment statusAssessment of Surrogates’ Knowledge of Patients’ Treatment Goals and Confidence in Their Ability to Make Surrogate Treatment Decisions
Fried TR, Zenoni M, Iannone L, O’Leary J. Assessment of Surrogates’ Knowledge of Patients’ Treatment Goals and Confidence in Their Ability to Make Surrogate Treatment Decisions. JAMA Internal Medicine 2019, 179: 267-268. PMID: 30477019, PMCID: PMC6440224, DOI: 10.1001/jamainternmed.2018.5299.Peer-Reviewed Original Research
2018
Increasing engagement in advance care planning using a behaviour change model: study protocol for the STAMP randomised controlled trials
Fried TR, Redding CA, Martino S, Paiva A, Iannone L, Zenoni M, Blakley LA, Rossi JS, O'Leary J. Increasing engagement in advance care planning using a behaviour change model: study protocol for the STAMP randomised controlled trials. BMJ Open 2018, 8: e025340. PMID: 30099405, PMCID: PMC6089328, DOI: 10.1136/bmjopen-2018-025340.Peer-Reviewed Original ResearchConceptsAdvance care planningUsual careCare planningACP engagementAppropriate Institutional Review BoardSafety Monitoring CommitteeComputer-tailored feedbackMotivational enhancement therapySurrogate decision makersInstitutional review boardHigh-quality endBehavior changePrimary outcomeEligible participantsPrimary careMedical recordsOutpatient practiceLife careVA sitesRandomisationEnhancement therapyMonitoring committeeReview boardCommunity studyBehavior change models
2017
Engagement in Advance Care Planning and Surrogates’ Knowledge of Patients’ Treatment Goals
Fried TR, Zenoni M, Iannone L, O'Leary J, Fenton BT. Engagement in Advance Care Planning and Surrogates’ Knowledge of Patients’ Treatment Goals. Journal Of The American Geriatrics Society 2017, 65: 1712-1718. PMID: 28317097, PMCID: PMC5555783, DOI: 10.1111/jgs.14858.Peer-Reviewed Original ResearchConceptsAdvance care planningQuantity of lifeTreatment goalsSurrogate knowledgeCare planningVeterans Affairs Medical CenterPatients' treatment goalsCohort study SETTINGKnowledge of patientsCommunity-dwelling veteransHealth care proxyLife-sustaining treatmentSurrogates' perspectivesMultivariable analysisPrimary careSevere illnessMedical CenterSevere physical disabilitiesVeterans' ratingsACP engagementProxy completionStudy settingPhysical disabilitySurrogate reportsSizeable proportion
2016
A Dyadic Perspective on Engagement in Advance Care Planning
Fried T, Zenoni M, Iannone L. A Dyadic Perspective on Engagement in Advance Care Planning. Journal Of The American Geriatrics Society 2016, 65: 172-178. PMID: 27910091, PMCID: PMC5258740, DOI: 10.1111/jgs.14497.Peer-Reviewed Original ResearchConceptsAdvance care planningCare planningACP engagementAge 55 yearsCross-sectional studyQualitative cross-sectional studyQuality of lifeLife-sustaining treatmentFacilitators of engagementSurrogate attitudesPatientsHealthcare proxySurrogates' needsLiving willsMedical decisionsClear communicationACP activity
2015
Lower Wingate Test Power Outcomes From "All-Out" Pretest Pedaling Cadence Compared With Moderate Cadence.
Lunn WR, Zenoni MA, Crandall IH, Dress AE, Berglund ML. Lower Wingate Test Power Outcomes From "All-Out" Pretest Pedaling Cadence Compared With Moderate Cadence. J Strength Cond Res 2015, 29: 2367-73. PMID: 26200017, DOI: 10.1519/JSC.0000000000000216.Peer-Reviewed Original Research
2014
Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial
Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD. Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial. JAMA 2014, 311: 2387-2396. PMID: 24866862, PMCID: PMC4266388, DOI: 10.1001/jama.2014.5616.Peer-Reviewed Original ResearchConceptsMajor mobility disabilityPhysical activity groupModerate-intensity physical activity programHealth education groupPhysical activity programHealth education programsMobility disabilityOlder adultsActivity programClinical trialsActivity groupPhysical activityIncident major mobility disabilityShort Physical Performance BatteryPersistent mobility disabilityPhysical activity preventsEducation groupSerious adverse eventsIndependent risk factorPhysical Performance BatteryDefinitive clinical trialsStructured physical activityVulnerable older adultsAdverse eventsLifestyle intervention