Featured Publications
Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria
Ding C, Wu Y, Dabas H, Hammarlund M. Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria. ELife 2022, 11: e73557. PMID: 35285800, PMCID: PMC8920508, DOI: 10.7554/elife.73557.Peer-Reviewed Original ResearchConceptsMAPK pathwayLoss of mitochondriaMitochondrial defectsUnbiased genetic screenMAP kinase pathwayCell-specific activationTrafficking complexGenetic screenCEBP-1Kinase pathwayUnderlying cellular mechanismsCellular mechanismsL-type voltage-gated calcium channelsMitochondriaVoltage-gated calcium channelsPathwayUNCAxon degenerationCaenorhabditisActivationCalcium channelsFurther analysisTraffickingSuppressesCaMKII
2023
A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans
Glomb O, Swaim G, Munoz LLancao P, Lovejoy C, Sutradhar S, Park J, Wu Y, Cason S, Holzbaur E, Hammarlund M, Howard J, Ferguson S, Gramlich M, Yogev S. A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans. Developmental Cell 2023, 58: 1847-1863.e12. PMID: 37751746, PMCID: PMC10574138, DOI: 10.1016/j.devcel.2023.08.031.Peer-Reviewed Original Research
2014
Axon regeneration in C. elegans
Hammarlund M, Jin Y. Axon regeneration in C. elegans. Current Opinion In Neurobiology 2014, 27: 199-207. PMID: 24794753, PMCID: PMC4122601, DOI: 10.1016/j.conb.2014.04.001.Peer-Reviewed Original Research
2012
Neural Regeneration in Caenorhabditis elegans
Bejjani R, Hammarlund M. Neural Regeneration in Caenorhabditis elegans. Annual Review Of Genetics 2012, 46: 499-513. PMID: 22974301, PMCID: PMC3700416, DOI: 10.1146/annurev-genet-110711-155550.Peer-Reviewed Original Research