2018
Comprehensive Genetic Analysis of Follicular Thyroid Carcinoma Predicts Prognosis Independent of Histology
Nicolson NG, Murtha TD, Dong W, Paulsson JO, Choi J, Barbieri AL, Brown TC, Kunstman JW, Larsson C, Prasad ML, Korah R, Lifton RP, Juhlin CC, Carling T. Comprehensive Genetic Analysis of Follicular Thyroid Carcinoma Predicts Prognosis Independent of Histology. The Journal Of Clinical Endocrinology & Metabolism 2018, 103: 2640-2650. PMID: 29726952, DOI: 10.1210/jc.2018-00277.Peer-Reviewed Original ResearchConceptsFollicular thyroid carcinomaThyroid carcinomaMutation burdenWorse disease-specific survivalDisease-specific survivalDifferent histopathological subtypesWorld Health Organization guidelinesSomatic mutationsNonsynonymous somatic mutationsHealth Organization guidelinesTotal mutation burdenIndependent predictorsWorse prognosisHistopathological subtypesPatient outcomesHistopathological classificationInvasive subtypesClinicopathologic parametersMutational burdenSurvival analysisSomatic copy number alterationsCopy number alterationsSubtypesOrganization guidelinesMore subclones
2014
Morphology predicts BRAFV600E mutation in papillary thyroid carcinoma: an interobserver reproducibility study
Virk RK, Theoharis CG, Prasad A, Chhieng D, Prasad ML. Morphology predicts BRAFV600E mutation in papillary thyroid carcinoma: an interobserver reproducibility study. Virchows Archiv 2014, 464: 435-442. PMID: 24549591, DOI: 10.1007/s00428-014-1552-3.Peer-Reviewed Original Research
2009
IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype
Walter O, Prasad M, Lu S, Quinlan R, Edmiston K, Khan A. IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype. Human Pathology 2009, 40: 1528-1533. PMID: 19695680, DOI: 10.1016/j.humpath.2009.05.005.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkers, TumorBreast NeoplasmsCarcinoma, Ductal, BreastDisease-Free SurvivalFemaleHumansImmunohistochemistryKaplan-Meier EstimateMiddle AgedNeoplasm ProteinsPhenotypeReceptor, ErbB-2Receptors, EstrogenReceptors, ProgesteroneRetrospective StudiesRNA-Binding ProteinsConceptsHuman epidermal growth factor receptor 2Invasive mammary carcinomaInvasive ductal carcinomaIMP3 expressionNovel biomarkersDuctal carcinomaProgesterone receptorMammary carcinomaBreast cancerEstrogen receptorAggressive phenotypeEpidermal growth factor receptor 2Triple-negative breast cancerDisease-free survivalBiologic prognostic factorsGrowth factor receptor 2Lymph node metastasisInsulin-like growth factor II mRNABasal-like carcinomasGrowth factor II mRNABasal epithelial markersNegative breast cancerBreast cancer casesFactor receptor 2Mouse monoclonal antibody
2000
Microinvasive Carcinoma (T1mic) of the Breast
Prasad M, Osborne M, Giri D, Hoda S. Microinvasive Carcinoma (T1mic) of the Breast. The American Journal Of Surgical Pathology 2000, 24: 422-428. PMID: 10716157, DOI: 10.1097/00000478-200003000-00012.Peer-Reviewed Original ResearchConceptsDuct carcinomaMicroinvasive carcinomaPositive axillary lymphChest wall recurrenceFoci of invasionHigh-grade nucleiUnderwent lumpectomyAxillary lymphTNM criteriaClinicopathologic dataTubular carcinomaMean ageInvasive fociRadiation therapyAnticytokeratin antibodyEquivocal casesMammographic abnormalitiesPatientsRoutine examinationCarcinomaMuscle actinHistologic slidesMean numberOcular micrometerMICB