2013
Diagnostic SOX10 gene signatures in salivary adenoid cystic and breast basal-like carcinomas
Ivanov SV, Panaccione A, Nonaka D, Prasad ML, Boyd KL, Brown B, Guo Y, Sewell A, Yarbrough WG. Diagnostic SOX10 gene signatures in salivary adenoid cystic and breast basal-like carcinomas. British Journal Of Cancer 2013, 109: 444-451. PMID: 23799842, PMCID: PMC3721393, DOI: 10.1038/bjc.2013.326.Peer-Reviewed Original ResearchConceptsBasal-like breast carcinomasAdenoid cystic carcinomaGene signatureBreast cancerSox10 expressionDiagnostic markerBasal-like carcinomasExpression of ERPotential molecular markersSensitive diagnostic markerPotential therapeutic targetBasal cell markersNovel diagnostic markerSalivary adenoid cystic carcinomaMyoepithelial featuresBreast subtypesAdenoid cysticBreast carcinomaCystic carcinomaImmunohistochemical stainingMolecular subtypesHistological similaritiesTherapeutic targetTranscriptional program characteristicDiagnostic significance
2009
IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype
Walter O, Prasad M, Lu S, Quinlan R, Edmiston K, Khan A. IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype. Human Pathology 2009, 40: 1528-1533. PMID: 19695680, DOI: 10.1016/j.humpath.2009.05.005.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkers, TumorBreast NeoplasmsCarcinoma, Ductal, BreastDisease-Free SurvivalFemaleHumansImmunohistochemistryKaplan-Meier EstimateMiddle AgedNeoplasm ProteinsPhenotypeReceptor, ErbB-2Receptors, EstrogenReceptors, ProgesteroneRetrospective StudiesRNA-Binding ProteinsConceptsHuman epidermal growth factor receptor 2Invasive mammary carcinomaInvasive ductal carcinomaIMP3 expressionNovel biomarkersDuctal carcinomaProgesterone receptorMammary carcinomaBreast cancerEstrogen receptorAggressive phenotypeEpidermal growth factor receptor 2Triple-negative breast cancerDisease-free survivalBiologic prognostic factorsGrowth factor receptor 2Lymph node metastasisInsulin-like growth factor II mRNABasal-like carcinomasGrowth factor II mRNABasal epithelial markersNegative breast cancerBreast cancer casesFactor receptor 2Mouse monoclonal antibody