Endothelin-1 and its role in the pathogenesis of infectious diseases
Freeman BD, Machado FS, Tanowitz HB, Desruisseaux MS. Endothelin-1 and its role in the pathogenesis of infectious diseases. Life Sciences 2014, 118: 110-119. PMID: 24780317, PMCID: PMC4538933, DOI: 10.1016/j.lfs.2014.04.021.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEndothelin-1Isoforms of endothelinRole of endothelinRickettsia conorii infectionPathogenesis of sepsisPro-inflammatory cytokinesVascular smooth muscle cellsLeukocyte adhesion moleculesSmooth muscle cellsSevere malariaVascular dysfunctionBacterial pneumoniaInflammatory mediatorsVascular tonePotent vasoconstrictorImmunomodulatory propertiesInfectious processAlveolar macrophagesPlatelet aggregationInfectious diseasesMuscle cellsEndothelinAdhesion moleculesPathogenesisChagas disease