2023
Family and personal history of cancer in the All of Us research program for precision medicine
Bruce L, Paul P, Kim K, Kim J, Keegan T, Hiatt R, Ohno-Machado L, Investigators O. Family and personal history of cancer in the All of Us research program for precision medicine. PLOS ONE 2023, 18: e0288496. PMID: 37459328, PMCID: PMC10351738, DOI: 10.1371/journal.pone.0288496.Peer-Reviewed Original ResearchMeSH KeywordsDatabases, FactualHumansNeoplasmsPopulation HealthPrecision MedicineSurveys and Questionnaires
2020
Engaging heart failure patients from a clinical data research network: A survey on willingness to participate in different types of research.
Choi Y, López J, Meeker D, Ohno-Machado L, Kim K. Engaging heart failure patients from a clinical data research network: A survey on willingness to participate in different types of research. AMIA Annual Symposium Proceedings 2020, 2019: 305-312. PMID: 32308823, PMCID: PMC7153117.Peer-Reviewed Original ResearchConceptsClinical Data Research NetworkHeart failure patientsLarge cohort studyResearch participationResearch NetworkCohort studyFailure patientsOne-time surveyPatient cohortObservational studyPatient motivationWeight controlSignificant associationClinical researchPatientsPrecision medicineHealth dataRecruitment effortsNational effortsActivity interestsSurgeryCohort
2018
Enhancing diversity to reduce health information disparities and build an evidence base for genomic medicine
Hindorff L, Bonham V, Ohno-Machado L. Enhancing diversity to reduce health information disparities and build an evidence base for genomic medicine. Personalized Medicine 2018, 15: 403-412. PMID: 30209973, PMCID: PMC6287493, DOI: 10.2217/pme-2018-0037.Peer-Reviewed Original Research
2017
Integrated precision medicine: the role of electronic health records in delivering personalized treatment
Sitapati A, Kim H, Berkovich B, Marmor R, Singh S, El‐Kareh R, Clay B, Ohno‐Machado L. Integrated precision medicine: the role of electronic health records in delivering personalized treatment. WIREs Mechanisms Of Disease 2017, 9 PMID: 28207198, PMCID: PMC5400726, DOI: 10.1002/wsbm.1378.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2016
Biospecimen Sharing Among Hispanic Women in a Safety-Net Clinic: Implications for the Precision Medicine Initiative
Nodora J, Komenaka I, Bouton M, Ohno-Machado L, Schwab R, Kim H, Farcas C, Perez G, Martinez M. Biospecimen Sharing Among Hispanic Women in a Safety-Net Clinic: Implications for the Precision Medicine Initiative. Journal Of The National Cancer Institute 2016, 109: djw201. PMID: 27688295, PMCID: PMC5040829, DOI: 10.1093/jnci/djw201.Peer-Reviewed Original ResearchConceptsSafety-net clinicsPrecision Medicine InitiativeHispanic womenUnderserved populationsMedicine InitiativeSafety-net hospitalUS Hispanic populationPatient's physicianIndividualized careConsent ratesBreast biopsyBiospecimen donationHispanic populationClinicHospitalResearch assistantsPhysiciansWomenPersonalized medicineBiospecimenPopulationBiopsy
2015
Tailoring informatics interventions to patients and healthcare providers
Ohno-Machado L. Tailoring informatics interventions to patients and healthcare providers. Journal Of The American Medical Informatics Association 2015, 22: 747-747. PMID: 26116707, DOI: 10.1093/jamia/ocv075.Commentaries, Editorials and Letters
2013
Making it personal: translational bioinformatics
Butte A, Ohno-Machado L. Making it personal: translational bioinformatics. Journal Of The American Medical Informatics Association 2013, 20: 595-596. PMID: 23757438, PMCID: PMC3721179, DOI: 10.1136/amiajnl-2013-002028.Commentaries, Editorials and Letters
2012
Calibrating predictive model estimates to support personalized medicine
Jiang X, Osl M, Kim J, Ohno-Machado L. Calibrating predictive model estimates to support personalized medicine. Journal Of The American Medical Informatics Association 2012, 19: 263-274. PMID: 21984587, PMCID: PMC3277613, DOI: 10.1136/amiajnl-2011-000291.Peer-Reviewed Original ResearchMeSH KeywordsConfidence IntervalsHumansLogistic ModelsMathematical ConceptsModels, TheoreticalPatient DischargePrecision MedicineConceptsReal-world medical classification problemsMedical classification problemsClassification problemPredictive model estimatesComputational complexityACP algorithmIsotonic regressionPredictive modelTerms of areaImportant performance measuresCalibration methodAdaptive techniqueCalculation of CIsAdaptive calibrationSquared errorIndividual predictionsPerformance measuresFit testInformationNew calibration methodCurrent methodsInformatics research to enable clinically relevant, personalized genomic medicine
Ohno-Machado L. Informatics research to enable clinically relevant, personalized genomic medicine. Journal Of The American Medical Informatics Association 2012, 19: 149-150. PMID: 22319175, PMCID: PMC3277638, DOI: 10.1136/amiajnl-2012-000844.Commentaries, Editorials and Letters