2023
Guiding Principles to Address the Impact of Algorithm Bias on Racial and Ethnic Disparities in Health and Health Care
Chin M, Afsar-Manesh N, Bierman A, Chang C, Colón-Rodríguez C, Dullabh P, Duran D, Fair M, Hernandez-Boussard T, Hightower M, Jain A, Jordan W, Konya S, Moore R, Moore T, Rodriguez R, Shaheen G, Snyder L, Srinivasan M, Umscheid C, Ohno-Machado L. Guiding Principles to Address the Impact of Algorithm Bias on Racial and Ethnic Disparities in Health and Health Care. JAMA Network Open 2023, 6: e2345050. PMID: 38100101, PMCID: PMC11181958, DOI: 10.1001/jamanetworkopen.2023.45050.Peer-Reviewed Original Research
2021
Racial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project
Karnes J, Arora A, Feng J, Steiner H, Sulieman L, Boerwinkle E, Clark C, Cicek M, Cohn E, Gebo K, Loperena-Cortes R, Ohno-Machado L, Mayo K, Mockrin S, Ramirez A, Schully S, Klimentidis Y. Racial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project. PLOS ONE 2021, 16: e0255583. PMID: 34358277, PMCID: PMC8345840, DOI: 10.1371/journal.pone.0255583.Peer-Reviewed Original ResearchConceptsBody mass indexBody fat distributionNon-Hispanic blacksNon-Hispanic whitesAlanine aminotransferaseNHB participantsFat distributionAge-adjusted obesity prevalenceNutrition Examination Survey dataBaseline physical examinationRace/ethnicityElectronic health recordsNHB womenWaist circumferenceMass indexHip ratioNHB menPhysical examinationNational HealthObesity prevalenceObesity ratesGender differencesObesityUs Research ProgramNHW participants
2019
Evaluating and sharing global genetic ancestry in biomedical datasets
Harismendy O, Kim J, Xu X, Ohno-Machado L. Evaluating and sharing global genetic ancestry in biomedical datasets. Journal Of The American Medical Informatics Association 2019, 26: 457-461. PMID: 30869786, PMCID: PMC6433181, DOI: 10.1093/jamia/ocy194.Peer-Reviewed Original ResearchConceptsGenetic diversity measurementsGenetic ancestryAvailable molecular datasetsHuman genetics researchCancer Genome Atlas (TCGA) datasetContinental resolutionGenetic diversityPhenotype-genotype associationsMolecular datasetsGlobal genetic ancestryAncestry informationGenetic researchAtlas datasetDiversity measurementsAncestryTraitsGlobal scaleDiversityBiomedical datasetsAvailable datasetsData repositoryDisease riskAccess datasetDatasetAvailable cohorts