2011
A Primer on the Current State of Microarray Technologies
Trachtenberg A, Robert J, Abdalla A, Fraser A, He S, Lacy J, Rivas-Morello C, Truong A, Hardiman G, Ohno-Machado L, Liu F, Hovig E, Kuo W. A Primer on the Current State of Microarray Technologies. Methods In Molecular Biology 2011, 802: 3-17. PMID: 22130870, DOI: 10.1007/978-1-61779-400-1_1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMicroarray technologyGenome-wide gene expression studiesAvailability of microarraysVariety of genesThousands of genesDNA microarray technologyDisease-specific genesGene expression studiesGene discoveryMolecular functioningExpression studiesGene expressionMolecular geneticsGenesComputer science analysisMicroarrayComplicated networkDisease statesDrug developmentNormal functioningMassive levelsDisease diagnosisGeneticsField of microarraysHigh levels
2002
Gene expression profiling by DNA microarrays and its application to dental research
Kuo W, Whipple M, Sonis S, Ohno-Machado L, Jenssen T. Gene expression profiling by DNA microarrays and its application to dental research. Oral Oncology 2002, 38: 650-656. PMID: 12353490, DOI: 10.1016/s1368-8375(02)00013-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGenome-wide gene expression studiesMicroarray technologyThousands of genesVariety of genesDNA microarray technologyGene expression studiesDisease-specific genesGene expression profilingGenetic profileGene discoveryMolecular functioningSpecific genesExpression profilingDNA microarraysExpression studiesMolecular geneticsIncorporation of DNAGenesIndividual patient's genetic profileDNAComplicated networkDisease statesDrug developmentNormal functioningMRNA expressionGene expression levels in different stages of progression in oral squamous cell carcinoma.
Kuo W, Jenssen T, Park P, Lingen M, Hasina R, Ohno-Machado L. Gene expression levels in different stages of progression in oral squamous cell carcinoma. AMIA Annual Symposium Proceedings 2002, 415-9. PMID: 12474876, PMCID: PMC2244435.Peer-Reviewed Original ResearchConceptsOral squamous cell carcinomaExpression levelsGene expression studiesGene expression dataGene expression levelsChromosome domainsCancer samplesExpression studiesSquamous cell carcinomaMolecular mechanismsExpression dataGenesMolecular levelProgression of OSCCCell carcinomaGenetic featuresCancer typesCommon cancer typesImportant insightsSignificant differencesSmall panelPatient samplesDifferent stagesProgressionSample types