Studies of NVP-BEZ235 in melanoma.
Sznol JA, Jilaveanu LB, Kluger HM. Studies of NVP-BEZ235 in melanoma. Current Cancer Drug Targets 2013, 13: 165-74. PMID: 23215722, DOI: 10.2174/1568009611313020006.Peer-Reviewed Original ResearchConceptsNVP-BEZ235Dual PI3K/mTOR inhibitorNovel dual PI3K/mTOR inhibitorPI3K/mTOR inhibitorSpecific molecular inhibitorsPotential escape mechanismsMTOR inhibitorsPI3K-pathwayEscape mechanismsMulti-level targetingMalignant melanocytesMolecular inhibitorsDrug developmentMelanomaAttractive targetInhibitorsPathwayNumerous studies