2024
Long-term cognitive effects of menopausal hormone therapy: Findings from the KEEPS Continuation Study
Gleason C, Dowling N, Kara F, James T, Salazar H, Simo C, Harman S, Manson J, Hammers D, Naftolin F, Pal L, Miller V, Cedars M, Lobo R, Malek-Ahmadi M, Kantarci K. Long-term cognitive effects of menopausal hormone therapy: Findings from the KEEPS Continuation Study. PLOS Medicine 2024, 21: e1004435. PMID: 39570992, PMCID: PMC11581397, DOI: 10.1371/journal.pmed.1004435.Peer-Reviewed Original ResearchConceptsOral conjugated equine estrogenLatent growth modelingLong-term cognitive effectsCognitive factor scoresCognitive benefitsCognitive performanceFactor scoresBaseline cognitionFollow-upClinical trialsEarly postmenopauseIn-person research visitsYears of follow-upRandomized to placeboMenopausal hormone therapyGlobal cognitive scoreNeuroimaging effectsCognitive measuresCognitive harmLongitudinal cohort studyCognitive changesCognitive slopesCognitive dataTest batteryCognitive functionAging and Adiposity—Focus on Biological Females at Midlife and Beyond
Rehman A, Lathief S, Charoenngam N, Pal L. Aging and Adiposity—Focus on Biological Females at Midlife and Beyond. International Journal Of Molecular Sciences 2024, 25: 2972. PMID: 38474226, PMCID: PMC10931752, DOI: 10.3390/ijms25052972.Peer-Reviewed Original Research
2023
Examining the association between urinary triclosan levels and menopausal status: results from the National Health and Nutrition Examination Survey, 2003 to 2016
Beroukhim G, Kayani J, Taylor H, Pal L. Examining the association between urinary triclosan levels and menopausal status: results from the National Health and Nutrition Examination Survey, 2003 to 2016. Menopause The Journal Of The North American Menopause Society 2023, 30: 906-912. PMID: 37625087, DOI: 10.1097/gme.0000000000002233.Peer-Reviewed Original ResearchConceptsMenopausal statusBody mass indexSmoking exposureMass indexNational HealthLinear regression analysisTCS levelsTriclosan levelsRetrospective cross-sectional studyMultivariable linear regression analysisReproductive health questionnaireUrinary triclosan levelsDuration of menopauseMultivariate linear regression analysisNutrition Examination SurveyCross-sectional studyYears of ageRegression analysisFemale participantsPostmenopausal statusPostmenopausal womenPremenopausal womenSurgical menopausePremature menopauseUrinary levels
2022
Associations between pituitary-ovarian hormones and cognition in recently menopausal women independent of type of hormone therapy
Kling J, Dowling N, Bimonte-Nelson H, Gleason C, Kantarci K, Stonnington C, Harman S, Naftolin F, Pal L, Cedars M, Manson J, James T, Brinton E, Miller V. Associations between pituitary-ovarian hormones and cognition in recently menopausal women independent of type of hormone therapy. Maturitas 2022, 167: 113-122. PMID: 36395695, PMCID: PMC10077876, DOI: 10.1016/j.maturitas.2022.10.002.Peer-Reviewed Original ResearchConceptsComplex attention tasksLatent growth curve modelsPoor cognitive performancePoorer global cognitionGrowth curve modelsAuditory attentionAttention taskCognitive factorsMental flexibilityVisual attentionExecutive functionCognitive domainsCognitive performanceCognitive trajectoriesGlobal cognitionPituitary-ovarian hormonesHormone therapyBaseline cognitionCognitionHormone levelsNeuropsychological testingMonth 18Menopausal womenEstrone levelsMonth 48