Higher systolic and diastolic blood pressures in recently postmenopausal women are associated with higher white matter hyperintensity volume more than a decade later in the keeps continuation study
Kara F, Tosakulwong N, Lesnick T, Schwarz C, Senjem M, Fields J, Min P, Lowe V, Jack C, Bailey K, James T, Lobo R, Manson J, Pal L, Hammers D, Malek‐Ahmadi M, Cedars M, Naftolin F, Miller V, Harman S, Dowling N, Gleason C, Kantarci K. Higher systolic and diastolic blood pressures in recently postmenopausal women are associated with higher white matter hyperintensity volume more than a decade later in the keeps continuation study. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.064187.Peer-Reviewed Original ResearchKronos Early Estrogen Prevention StudyDiastolic blood pressureGreater WMH volumeWM injuryWMH volumeWM hyperintensitiesPostmenopausal womenBlood pressureMenopausal transitionRisk factorsHigher white matter hyperintensity volumeWaist/hip ratioWhite matter hyperintensity volumeHormone therapy trialsCVD risk factorsMenopausal hormone therapyWM integrityWhite matter injuryAssociation of BPBetter cardiovascular healthEarly postmenopausal stageLow-density lipoproteinContinuation studyTotal intracranial volumeBaseline SBP