2022
Management of Patients on Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Peri-Endoscopic Period: A Clinical Practice Guideline Dissemination Tool
Barkun AN, Douketis J, Noseworthy PA, Laine L, Telford JJ, Abraham NS. Management of Patients on Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Peri-Endoscopic Period: A Clinical Practice Guideline Dissemination Tool. The American Journal Of Gastroenterology 2022, 117: 513-519. PMID: 35354773, DOI: 10.14309/ajg.0000000000001688.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
Timing of Endoscopy in Patients Hospitalized with Upper Gastrointestinal Bleeding
Laine L. Timing of Endoscopy in Patients Hospitalized with Upper Gastrointestinal Bleeding. New England Journal Of Medicine 2020, 382: 1361-1363. PMID: 32242363, DOI: 10.1056/nejme2002121.Commentaries, Editorials and LettersChromoendoscopy meta-analysis: correcting subgroup analysis interpretation
Laine L, Kaltenbach T, Barkun A, Soetikno R. Chromoendoscopy meta-analysis: correcting subgroup analysis interpretation. Gastrointestinal Endoscopy 2020, 91: 719. PMID: 32087902, DOI: 10.1016/j.gie.2019.08.041.Commentaries, Editorials and Letters
2019
MAP(ASH): A new scoring system for the prediction of intervention and mortality in upper gastrointestinal bleeding
Redondo‐Cerezo E, Vadillo‐Calles F, Stanley AJ, Laursen S, Laine L, Dalton HR, Ngu JH, Schultz M, Jiménez‐Rosales R. MAP(ASH): A new scoring system for the prediction of intervention and mortality in upper gastrointestinal bleeding. Journal Of Gastroenterology And Hepatology 2019, 35: 82-89. PMID: 31359521, DOI: 10.1111/jgh.14811.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal bleedingGastrointestinal bleedingEndoscopic interventionGlasgow-Blatchford scoreSystolic blood pressureNew scoring systemBlatchford scoreProspective databaseBlood pressureRisk stratificationValidation cohortDevelopment cohortOriginal cohortEmergency roomMental statusRisk scoreClinical practiceFair discriminationScoring systemPatientsMortalityCohortNew scoreInterventionBleeding
2016
Upper Gastrointestinal Bleeding Due to a Peptic Ulcer
Laine L. Upper Gastrointestinal Bleeding Due to a Peptic Ulcer. New England Journal Of Medicine 2016, 374: 2367-2376. PMID: 27305194, DOI: 10.1056/nejmcp1514257.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2008
Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension
de Franchis R, Eisen GM, Laine L, Fernandez‐Urien I, Herrerias JM, Brown RD, Fisher L, Vargas HE, Vargo J, Thompson J, Eliakim R. Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension. Hepatology 2008, 47: 1595-1603. PMID: 18435461, DOI: 10.1002/hep.22227.Peer-Reviewed Original ResearchConceptsEsophageal varicesEsophageal capsule endoscopyNegative predictive valuePositive predictive valuePredictive valueCapsule endoscopyPortal hypertensionLarge esophageal varicesVariceal gradeLarge varicesMulticenter trialCurrent guidelinesEsophagogastroduodenoscopyTreatment decisionsVaricesCapsule studyPatientsEndoscopyPilot studyDiagnostic performanceEquivalence studyKappa scoresMinimal invasivenessCirrhosisHypertension
1999
Fingerstick Helicobacter pylori antibody test: better than laboratory serological testing?
Faigel D, Vartan G, Knigge K, Laine L, Fennerty M, Margaret N, Marquis S. Fingerstick Helicobacter pylori antibody test: better than laboratory serological testing? The American Journal Of Gastroenterology 1999, 94: ajg1999810. PMID: 10606304, DOI: 10.1111/j.1572-0241.1999.01510.x.Peer-Reviewed Original Research
1997
Management of actively bleeding esophageal varices
Laine L. Management of actively bleeding esophageal varices. Gastrointestinal Endoscopy 1997, 46: 83-84. PMID: 9260714, DOI: 10.1016/s0016-5107(97)70218-9.Commentaries, Editorials and Letters
1995
Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis.
Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Annals Of Internal Medicine 1995, 123: 280-7. PMID: 7611595, DOI: 10.7326/0003-4819-123-4-199508150-00007.Peer-Reviewed Original ResearchConceptsEsophageal variceal bleedingTreatment of patientsEndoscopic ligationVariceal bleedingEsophageal varicesEndoscopic treatmentDuplicate data abstractionDuplicate independent reviewEndoscopic treatment sessionsRate of deathRelevant primary articlesReview of citationsVariceal obliterationBacterial peritonitisLigation therapyPulmonary infectionEsophageal strictureMethodologic qualitySclerotherapyMortality rateTreatment sessionsPatientsRelevant articlesPrimary investigatorUnpublished studies
1992
Prospective evaluation of immediate versus delayed refeeding and prognostic value of endoscopy in patients with upper gastrointestinal hemorrhage
Laine L, Cohen H, Brodhead J, Cantor D, Garcia F, Mosquera M. Prospective evaluation of immediate versus delayed refeeding and prognostic value of endoscopy in patients with upper gastrointestinal hemorrhage. Gastroenterology 1992, 102: 314-316. PMID: 1727765, DOI: 10.1016/0016-5085(92)91816-m.Peer-Reviewed Original ResearchMeSH KeywordsEndoscopyFoodGastrointestinal HemorrhageHumansPrognosisProspective StudiesRecurrenceTime FactorsConceptsMallory-Weiss tearUpper gastrointestinal hemorrhageGastrointestinal hemorrhagePrognostic valueRegular dietMajor upper gastrointestinal hemorrhageClean-based ulcersEndoscopic evidenceHospital courseRecurrent bleedingEndoscopic findingsMajor hemorrhageClinical evidenceProspective evaluationVs. 5Entry criteriaClean baseVs. 2Lower riskPatientsUlcersUrgent interventionVs. 1HemorrhageTears
1989
Multipolar electrocoagulation in the treatment of peptic ulcers with nonbleeding visible vessels. A prospective, controlled trial.
Laine L. Multipolar electrocoagulation in the treatment of peptic ulcers with nonbleeding visible vessels. A prospective, controlled trial. Annals Of Internal Medicine 1989, 110: 510-4. PMID: 2647014, DOI: 10.7326/0003-4819-110-7-510.Peer-Reviewed Original ResearchConceptsNonbleeding visible vesselMultipolar electrocoagulationVisible vesselControl groupMajor upper gastrointestinal hemorrhageMean transfusion requirementSham-controlled trialUpper gastrointestinal hemorrhageUnstable vital signsSafety of treatmentCost of hospitalizationUnits of bloodEndoscopic evidenceGastrointestinal hemorrhageTransfusion requirementsUrgent surgeryEmergency surgeryHospital daysEndoscopic treatmentOverall mortalityPeptic ulcerCounty HospitalAspirate samplesDiagnostic endoscopyTreatment groups