2021
Antiplatelet Monotherapy Is Associated with an Increased Risk of Bleeding After Endoscopic Sphincterotomy
Zakko A, Zakko L, Grimshaw AA, Laine L. Antiplatelet Monotherapy Is Associated with an Increased Risk of Bleeding After Endoscopic Sphincterotomy. Digestive Diseases And Sciences 2021, 67: 4161-4169. PMID: 34796411, DOI: 10.1007/s10620-021-07302-w.Peer-Reviewed Original ResearchMeSH KeywordsAdultAspirinCholangiopancreatography, Endoscopic RetrogradeHemorrhageHumansPlatelet Aggregation InhibitorsSphincterotomy, EndoscopicConceptsEndoscopic retrograde cholangiopancreatographyPost-sphincterotomy bleedingAntiplatelet monotherapyInclusion criteriaRisk of bleedingROBINS-I toolNewcastle-Ottawa ScaleHigh-quality studiesRandom-effects modelBackgroundClinical guidelinesAntithrombotic therapyAdult patientsCohort studyEndoscopic sphincterotomyPrimary outcomeAntiplatelet agentsOvid EmbaseRetrograde cholangiopancreatographyCochrane LibraryOvid MEDLINEMonotherapyMethodological qualityBleedingUnique citationsPatients
2020
Musculoskeletal Pain Symptoms and Injuries Among Endoscopists Who Perform ERCP
Campbell EV, Muniraj T, Aslanian HR, Laine L, Jamidar P. Musculoskeletal Pain Symptoms and Injuries Among Endoscopists Who Perform ERCP. Digestive Diseases And Sciences 2020, 66: 56-62. PMID: 32144599, DOI: 10.1007/s10620-020-06163-z.Peer-Reviewed Original ResearchMeSH KeywordsCholangiopancreatography, Endoscopic RetrogradeCross-Sectional StudiesFemaleGastroenterologistsHumansMaleMusculoskeletal PainOccupational ExposurePain MeasurementRisk FactorsSurveys and QuestionnairesConceptsEndoscopic retrograde cholangiopancreatographyMusculoskeletal pain symptomsPain symptomsRisk factorsMusculoskeletal injuriesPrevalent musculoskeletal injuriesDe Quervain's tenosynovitisPotential risk factorsRisk of injuryAnonymous electronic surveyNeck painBack painQuervain's tenosynovitisRetrograde cholangiopancreatographyResultsA totalPreventative strategiesConclusionsThe majorityInjurySymptomsEndoscopistsProtective gearMultiple studiesHalf reportTenosynovitisElectronic survey
2017
Optimal Timing of Endoscopic Retrograde Cholangiopancreatography in Acute Cholangitis
Hou LA, Laine L, Motamedi N, Sahakian A, Lane C, Buxbaum J. Optimal Timing of Endoscopic Retrograde Cholangiopancreatography in Acute Cholangitis. Journal Of Clinical Gastroenterology 2017, 51: 534-538. PMID: 27875357, DOI: 10.1097/mcg.0000000000000763.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAgedAged, 80 and overCholangiopancreatography, Endoscopic RetrogradeCholangitisFemaleHospitalizationHumansIntensive Care UnitsIntubation, IntratrachealLength of StayMaleMiddle AgedMultivariate AnalysisProspective StudiesTime FactorsTreatment OutcomeYoung AdultConceptsEndoscopic retrograde cholangiopancreatographyIntensive care unit admissionCare unit admissionLength of hospitalizationAcute cholangitisUnit admissionRetrograde cholangiopancreatographyFrequent intensive care unit admissionOptimal timingAdditional adverse outcomesCases of cholangitisProcedural adverse eventsDays of presentationVasopressor requirementVasopressor supportBiliary decompressionHospital stayVasopressor useSecondary outcomesAdverse eventsAntibiotic therapyPrimary outcomeEndotracheal intubationAdverse outcomesEmergency departmentPredictors and outcomes of delayed plastic biliary stent removal following endoscopic retrograde cholangiopancreatography
Kim SJ, Ohanian E, Lee F, Nam B, Che K, Laine L, Kim SE, Kim JJ. Predictors and outcomes of delayed plastic biliary stent removal following endoscopic retrograde cholangiopancreatography. Scandinavian Journal Of Gastroenterology 2017, 52: 1128-1132. PMID: 28657377, DOI: 10.1080/00365521.2017.1342138.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAmbulatory CareAnesthesiaCholangiopancreatography, Endoscopic RetrogradeCholangitisCholedocholithiasisCholestasisCritical CareDevice RemovalFemaleHumansLanguageLength of StayMaleMiddle AgedPlasticsProsthesis FailureRisk FactorsStentsTime FactorsConceptsEndoscopic retrograde cholangiopancreatographyBiliary stent removalBiliary stent placementStent removalStent obstructionRetrograde cholangiopancreatographyStent placementIndex endoscopic retrograde cholangiopancreatographyNon-English primary languageOutcomes of patientsOutpatient endoscopic retrograde cholangiopancreatographyPreventable adverse eventsMultivariable regression analysisUniversity Medical CenterPlastic biliary stentsAnesthesia assistanceBaseline characteristicsAdverse eventsConsecutive patientsClinical outcomesLoma Linda University Medical CenterOne-fifthMedical CenterBiliary stentsLower odds
2016
Randomized Trial of Endoscopist-Controlled vs. Assistant-Controlled Wire-Guided Cannulation of the Bile Duct
Buxbaum J, Leonor P, Tung J, Lane C, Sahakian A, Laine L. Randomized Trial of Endoscopist-Controlled vs. Assistant-Controlled Wire-Guided Cannulation of the Bile Duct. The American Journal Of Gastroenterology 2016, 111: 1841. PMID: 27377519, DOI: 10.1038/ajg.2016.268.Peer-Reviewed Original ResearchMeSH KeywordsAdultBile DuctsCatheterizationCholangiopancreatography, Endoscopic RetrogradeCholangitisEarly Termination of Clinical TrialsFemaleGastroenterologistsHemorrhageHumansIntraoperative ComplicationsLogistic ModelsMaleMiddle AgedMultivariate AnalysisNursesPancreatitisPatient SafetyPostoperative ComplicationsPostoperative HemorrhageConceptsBile duct cannulationEndoscopic retrograde cholangiopancreatographySafety end pointDuct cannulationBiliary cannulationInterim analysisWire guidanceComposite safety end pointComplications of ERCPEnd pointPrimary efficacy outcomePost-ERCP pancreatitisSuccessful biliary cannulationSignificant differencesEfficacy outcomesRandomized trialsBile ductRetrograde cholangiopancreatographyCannulation attemptsCannulationPatientsSphincterotomePancreatitisSignificant increaseLower rates
2015
Can a Computerized Simulator Assess Skill Level and Improvement in Performance of ERCP?
Sahakian AB, Laine L, Jamidar PA, Siddiqui UD, Duffy A, Ciarleglio MM, Deng Y, Nagar A, Aslanian HR. Can a Computerized Simulator Assess Skill Level and Improvement in Performance of ERCP? Digestive Diseases And Sciences 2015, 61: 722-730. PMID: 26572779, DOI: 10.1007/s10620-015-3939-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultCholangiopancreatography, Endoscopic RetrogradeClinical CompetenceCohort StudiesComputer SimulationEducational MeasurementFaculty, MedicalFellowships and ScholarshipsGastroenterologyHumansMiddle AgedOperative TimeProspective StudiesQuality ImprovementTertiary Care CentersConceptsTotal procedure timeProcedure timePrimary outcomeAcademic tertiary referral centerShorter total procedure timeTertiary referral centerPerformance of ERCPReferral centerCohort studyRetrograde cholangiographyERCP proceduresTrainee experienceGastroenterology fellowsSurgical skills centerFlexible endoscopyERCP trainingLittle dataGastroenterology facultyERCPSignificant differencesConsiderable riskSession 2Session 1Baseline sessionsOutcomesDelayed endoscopic retrograde cholangiopancreatography is associated with persistent organ failure in hospitalised patients with acute cholangitis
Lee F, Ohanian E, Rheem J, Laine L, Che K, Kim JJ. Delayed endoscopic retrograde cholangiopancreatography is associated with persistent organ failure in hospitalised patients with acute cholangitis. Alimentary Pharmacology & Therapeutics 2015, 42: 212-220. PMID: 25997554, DOI: 10.1111/apt.13253.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAged, 80 and overCholangiopancreatography, Endoscopic RetrogradeCholangitisComorbidityFemaleHospitalizationHumansMaleMiddle AgedMultiple Organ FailureMultivariate AnalysisRetrospective StudiesSystemic Inflammatory Response SyndromeConceptsEarly endoscopic retrograde cholangiopancreatographyPersistent organ failureEarly ERCPOrgan failureEndoscopic retrograde cholangiopancreatographyAcute cholangitisRetrograde cholangiopancreatographySystemic inflammatory response syndromeConsecutive hospitalised patientsCharlson Comorbidity IndexInflammatory response syndromeRelative risk increaseComorbidity indexHospitalised patientsPrimary outcomeResponse syndromeBenign obstructionMalignant stricturesCholangitisPatientsMultivariate analysisRisk increaseHospitalisationHypoalbuminemiaBacteremia
2014
Lower Yield of Endoscopic Ultrasound-Guided Fine-Needle Aspiration in Patients with Pancreatic Head Mass with a Biliary Stent
Kim JJ, Walia S, Lee SH, Patel B, Vetsa M, Zhao Y, Srikureja W, Laine L. Lower Yield of Endoscopic Ultrasound-Guided Fine-Needle Aspiration in Patients with Pancreatic Head Mass with a Biliary Stent. Digestive Diseases And Sciences 2014, 60: 543-549. PMID: 25245115, DOI: 10.1007/s10620-014-3367-0.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedCholangiopancreatography, Endoscopic RetrogradeEndoscopic Ultrasound-Guided Fine Needle AspirationFemaleHumansJaundice, ObstructiveMaleMiddle AgedMultivariate AnalysisOdds RatioPalliative CarePancreatic NeoplasmsPredictive Value of TestsRetrospective StudiesRisk FactorsStentsTime FactorsTreatment OutcomeConceptsEndoscopic ultrasound-guided fine-needle aspirationEndoscopic retrograde cholangiopancreatographyBiliary stentsFine-needle aspirationJaundiced patientsPancreatic cancerFinal diagnosisHistologic diagnosisPancreatic massOnsite cytopathologistUltrasound-guided fine-needle aspirationPancreatic head massHistologic accuracyResultsMean ageMethodsConsecutive patientsPrimary endpointRadiologic evaluationRetrograde cholangiopancreatographyCore biopsyEndoscopic ultrasoundPatientsMultivariate analysisStentsMalignancyDiagnosis
2013
Aggressive Hydration With Lactated Ringer's Solution Reduces Pancreatitis After Endoscopic Retrograde Cholangiopancreatography
Buxbaum J, Yan A, Yeh K, Lane C, Nguyen N, Laine L. Aggressive Hydration With Lactated Ringer's Solution Reduces Pancreatitis After Endoscopic Retrograde Cholangiopancreatography. Clinical Gastroenterology And Hepatology 2013, 12: 303-307.e1. PMID: 23920031, PMCID: PMC3879172, DOI: 10.1016/j.cgh.2013.07.026.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmylasesCholangiopancreatography, Endoscopic RetrogradeFemaleHumansIsotonic SolutionsMaleMiddle AgedPain MeasurementPancreatitisPilot ProjectsRinger's LactateRisk FactorsConceptsEndoscopic retrograde cholangiopancreatographyPost-ERCP pancreatitisAggressive hydrationStandard hydrationVolume overloadEpigastric painRetrograde cholangiopancreatographyRinger's solutionFirst-time endoscopic retrograde cholangiopancreatographyVisual analogue pain scoreEnd pointPilot studyAggressive intravenous hydrationAnalog pain scoresIncidence of pancreatitisPrimary end pointSecondary end pointsCommon serious complicationLactated Ringer's solutionPeriprocedural hydrationIntravenous hydrationPain scoresSerious complicationsSerum levelsPancreatitis
1999
An evidence-based approach to gastroenterology diagnosis
Schoenfeld* P, Guyatt‡ G, Hamilton§ F, Laine∥ L, Cook‡ D, Bjorkman¶ D, Morgan# D, Peterson** W, Group F. An evidence-based approach to gastroenterology diagnosis. Gastroenterology 1999, 116: 1230-1237. PMID: 10220515, DOI: 10.1016/s0016-5085(99)70026-0.Peer-Reviewed Original ResearchCholangiopancreatography, Endoscopic RetrogradeDiagnostic Techniques, Digestive SystemEvidence-Based MedicineGallstonesGastroenterologyHumansLikelihood FunctionsMagnetic Resonance ImagingPredictive Value of Tests