2015
Management of Diminutive Colon Polyps Based on Endoluminal Imaging
Lieberman D, Brill J, Canto M, DeMarco D, Fennerty B, Gupta N, Laine L, Lightdale C, Montgomery E, Odze R, Rex D, Sharma P, Kochman M, Tokar J. Management of Diminutive Colon Polyps Based on Endoluminal Imaging. Clinical Gastroenterology And Hepatology 2015, 13: 1860-1866. PMID: 26192139, DOI: 10.1016/j.cgh.2015.07.011.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDiminutive colon polypsSuch polypsColon polypsAppropriate surveillance intervalsNegative predictive valuePatient education needsDiminutive hyperplastic polypsEndoluminal imagingNon-neoplastic polypsEndoscopic impressionPathologic evaluationSurveillance intervalsPathologic diagnosisDiminutive adenomasHyperplastic polypsSerious pathologyClinical practicePredictive valuePolypsPractice changeVivo studiesExpert panelAdenomasPotential cost benefitsRisk
2004
The hepatotoxicity of non‐steroidal anti‐inflammatory drugs
Rubenstein JH, Laine L. The hepatotoxicity of non‐steroidal anti‐inflammatory drugs. Alimentary Pharmacology & Therapeutics 2004, 20: 373-380. PMID: 15298630, DOI: 10.1111/j.1365-2036.2004.02092.x.Peer-Reviewed Original ResearchConceptsNon-steroidal anti-inflammatory drug usersNon-steroidal anti-inflammatory drugsAnti-inflammatory drugsLiver injuryDrug usersParticular non-steroidal anti-inflammatory drugsComparative riskPopulation-based epidemiological studyRare complicationExcess riskRelevant hepatotoxicityInclusion criteriaMethodological qualityEpidemiological studiesPrecise riskPatient countsCumulative exposureInjuryHospitalizationDrugsRiskHepatotoxicityIncidenceCurrent useDeathThe epidemiology of ischaemic colitis
Higgins PD, Davis KJ, Laine L. The epidemiology of ischaemic colitis. Alimentary Pharmacology & Therapeutics 2004, 19: 729-738. PMID: 15043513, DOI: 10.1111/j.1365-2036.2004.01903.x.Peer-Reviewed Original ResearchConceptsIschemic colitisRisk factorsPopulation-based sampleGeneral populationPopulation incidenceChronic obstructive pulmonary diseaseCo-morbid conditionsIrritable bowel syndromeObstructive pulmonary diseasePopulation-based studyGeneral population incidenceBowel syndromePulmonary diseaseCase seriesBaseline incidenceCase reportAdvanced ageVascular surgeryColitisEligible articlesIncidencePopulation samplePrevalenceRiskBibliographic databasesGuidelines for the appropriate use of non‐steroidal anti‐inflammatory drugs, cyclo‐oxygenase‐2‐specific inhibitors and proton pump inhibitors in patients requiring chronic anti‐inflammatory therapy
Dubois RW, Melmed GY, Henning JM, Laine L. Guidelines for the appropriate use of non‐steroidal anti‐inflammatory drugs, cyclo‐oxygenase‐2‐specific inhibitors and proton pump inhibitors in patients requiring chronic anti‐inflammatory therapy. Alimentary Pharmacology & Therapeutics 2004, 19: 197-208. PMID: 14723611, DOI: 10.1111/j.0269-2813.2004.01834.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsProton pump inhibitorsCost of NSAIDsPump inhibitorsGastrointestinal eventsChronic anti-inflammatory therapyRAND/UCLA Appropriateness MethodNon-steroidal anti-inflammatory drugsAnti-inflammatory therapyAnti-inflammatory drugsDrug treatment strategiesCommunity-based settingsCardiovascular riskProphylactic useAppropriateness MethodTreatment strategiesLower riskNSAIDsPatientsClinical scenariosAspirinAppropriate useInhibitorsRiskCare entitiesLiterature review
2001
Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient
Laine L. Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient. Gastroenterology 2001, 120: 594-606. PMID: 11179238, DOI: 10.1053/gast.2001.21907.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory drugsGI eventsGI diseasePrevention of NSAIDAnti-inflammatory drug useClinical upper GI eventsHistory of ulcerUpper GI eventsHalf of patientsHigh-risk patientsAnti-inflammatory drugsGastrointestinal eventsNSAID doseGastroduodenal injuryNSAID usersClinical featuresGastric erosionsSteroid useCommon causeDrug usePatientsUlcersDiseaseRiskUnited States today