2021
5′-Phosphorylation Strengthens Sticky-End Cohesions
Li Z, Zheng M, Liu L, Seeman N, Mao C. 5′-Phosphorylation Strengthens Sticky-End Cohesions. Journal Of The American Chemical Society 2021, 143: 14987-14991. PMID: 34516099, DOI: 10.1021/jacs.1c07279.Peer-Reviewed Original ResearchSticky-ended cohesionDNA crystalsSelf-assembly kineticsFree energy calculationsNucleic acid nanotechnologyMolecular mechanicsChemical modificationNatural DNACrystal morphologyEnergy calculationsCrystal growthSynthetic DNACrystallization processCrystallization kineticsCrystalsKineticsPotential differenceNanotechnologyHereinMorphologyCalculationsDNA origami
Dey S, Fan C, Gothelf K, Li J, Lin C, Liu L, Liu N, Nijenhuis M, Saccà B, Simmel F, Yan H, Zhan P. DNA origami. Nature Reviews Methods Primers 2021, 1: 13. DOI: 10.1038/s43586-020-00009-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDNA origami technologyOrigami technologyDNA origami techniqueNear-atomic precisionDNA nanotechnologyOrigami techniqueDNA origamiDrug deliveryOrigami structuresMolecular machinesOrigami designBiological materialsLiving cellsSynthesisVivo synthesisNanophotonicsNanotechnologyNanofabricationNanostructuresNanoelectronicsBioimagingScale of productionFabricationTechnologyFunctionalization
2019
Making Engineered 3D DNA Crystals Robust
Li Z, Liu L, Zheng M, Zhao J, Seeman N, Mao C. Making Engineered 3D DNA Crystals Robust. Journal Of The American Chemical Society 2019, 141: 15850-15855. PMID: 31553173, DOI: 10.1021/jacs.9b06613.Peer-Reviewed Original ResearchConceptsDNA crystalsDNA nanotechnologyMacroscopic devicesCovalent bondsProtein entrapmentSticky endsCrystal stabilityCrystal shellsCrystal contactsNew opportunitiesComplex architectureCrystalsMolecular levelNanotechnologyFabricationBiocatalysisApplicationsKey obstacleBondsDevicesScaffoldsShellArchitectureMatryoshka dollsStability