2020
Organization, Function, and Development of the Mouse Retinogeniculate Synapse
Liang L, Chen C. Organization, Function, and Development of the Mouse Retinogeniculate Synapse. Annual Review Of Vision Science 2020, 6: 261-285. PMID: 32936733, DOI: 10.1146/annurev-vision-121219-081753.Peer-Reviewed Original ResearchConceptsRetinogeniculate synapseDistinct retinal ganglion cell typesRetinal ganglion cell typesGanglion cell typesImage-forming pathwayVisual thalamusThalamocortical neuronsVisual pathwayExperimental modelCircuit organizationThalamusSynapseMiceCell typesFunctional organizationRecent studiesPowerful experimental modelCurrent understandingVisual spaceVisual experiencePathwayNeuronsRGCs
2017
Is it appropriate to measure age-related lumbar disc degeneration on the mid-sagittal MR image? A quantitative image study
Hu X, Chen M, Pan J, Liang L, Wang Y. Is it appropriate to measure age-related lumbar disc degeneration on the mid-sagittal MR image? A quantitative image study. European Spine Journal 2017, 27: 1073-1081. PMID: 29147797, DOI: 10.1007/s00586-017-5357-3.Peer-Reviewed Original ResearchConceptsMid-sagittal magnetic resonance imagingMagnetic resonance imagingPosterior disc bulgingMeasures of disc degenerationAssociated with ageDisc bulgeDisc degenerationDisc heightSpine magnetic resonance imagingAge-related disc degenerationT2-weighted magnetic resonance imagingSagittal magnetic resonance imagingDisc signal intensityLumbar disc degenerationSevere disc degenerationDisc height measurementsMid-sagittal MR imagesDisc narrowingSignal intensity measurementsMR imagingResonance imagingDegenerationAgeSignal intensityPhenotypeIn Vivo Imaging of CNS Injury and Disease
Akassoglou K, Merlini M, Rafalski VA, Real R, Liang L, Jin Y, Dougherty SE, De Paola V, Linden DJ, Misgeld T, Zheng B. In Vivo Imaging of CNS Injury and Disease. Journal Of Neuroscience 2017, 37: 10808-10816. PMID: 29118209, PMCID: PMC5678013, DOI: 10.1523/jneurosci.1826-17.2017.Peer-Reviewed Original ResearchConceptsCNS injuryNeural transplantationGlial responseNeurovascular unitAxonal degenerationSpinal cordMammalian CNSRodent brainCellular responsesInjuryDiseaseVivo imagingImagingOptical imagingNeuroinflammationResponseMini-SymposiumTransplantationGlialCordTherapyCNSDegenerationImportant new insightsBrain
2010
The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis
Potter CJ, Tasic B, Russler EV, Liang L, Luo L. The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis. Cell 2010, 141: 536-548. PMID: 20434990, PMCID: PMC2883883, DOI: 10.1016/j.cell.2010.02.025.Peer-Reviewed Original ResearchConceptsMARCM analysisQa gene clusterCell division patternsBinary expression systemTransgene expression patternsTransgene expressionGAL4 systemGene functionMosaic analysisGene clusterRegulatory genesMammalian cellsCell divisionDivision patternsLow basal expressionLineage tracingExpression systemExpression patternsNeuronal lineageOlfactory attractionCell growthBasal expressionDrosophilaRepressionExpression