SV40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics
Greenwood J, Pryce G, Devine L, Male D, dos Santos W, Calder V, Adamson P. SV40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics. Journal Of Neuroimmunology 1996, 71: 51-63. PMID: 8982103, DOI: 10.1016/s0165-5728(96)00130-0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, Polyomavirus TransformingAntigens, SurfaceBiological TransportBlood-Brain BarrierCell Adhesion MoleculesCell MovementCell Transformation, ViralEndotheliumEndothelium, VascularFluorescent Antibody Technique, IndirectHistocompatibility AntigensLipoproteins, LDLPigment Epithelium of EyeRatsRetinaSimian virus 40T-LymphocytesConceptsRetinal pigment epitheliumBlood-retinal barrierRetinal endotheliumAdhesion moleculesCell adhesion moleculeCell linesAntigen-specific T cell linesImmortalised cell linesMajor histocompatibility complex class 1Vascular cell adhesion moleculeRat brain endotheliumMHC class IIEndothelial cell adhesion moleculesIntercellular adhesion moleculeCentral nervous systemLectin Griffonia simplicifoliaPlatelet endothelial cell adhesion moleculeHigh-affinity uptakeT cell linesPigmented epithelial cellsRPE cell lineVon Willebrand factorEndothelial cell lineNeural parenchymaBrain endotheliumRole of LFA‐1, ICAM‐1, VLA‐4 and VCAM‐1 in lymphocyte migration across retinal pigment epithelial monolayers in vitro
DEVINE L, LIGHTMAN S, GREENWOOD J. Role of LFA‐1, ICAM‐1, VLA‐4 and VCAM‐1 in lymphocyte migration across retinal pigment epithelial monolayers in vitro. Immunology 1996, 88: 456-462. PMID: 8774365, PMCID: PMC1456340, DOI: 10.1046/j.1365-2567.1996.d01-666.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood-Retinal BarrierCD4-Positive T-LymphocytesCell Adhesion MoleculesCell Culture TechniquesCell MovementChemotaxis, LeukocyteEnzyme-Linked Immunosorbent AssayFlow CytometryIntercellular Adhesion Molecule-1Microscopy, ElectronPigment Epithelium of EyeRatsRats, Inbred StrainsVascular Cell Adhesion Molecule-1ConceptsBlood-retinal barrierRetinal pigment epitheliumLFA-1 betaICAM-1VCAM-1VLA-4Vascular endotheliumLymphocyte migrationAntigen-specific T cell linesAdhesion moleculesRetinal vascular endotheliumMigration of CD4Traffic of lymphocytesOcular inflammatory conditionsLFA-1 alphaVCAM-1 expressionRetinal pigment epithelial monolayerRPE cell monolayersT cell linesPosterior uveitisLymphocyte trafficInflammatory conditionsPosterior barrierCell adhesion moleculeIFN-gamma